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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
15929 10058-F4 New 403811-55-2 ≥95% 2014-04-18 0E-12 10058-f4 inhibitors cancers apoptosis genes regulations transcription factors oncogenes Myc Max dimer regulates proteins c-Myc cells growth 10058F4 10058 F4 permeable thiazolidione inhibits inhibition inhibitors proliferation cycles arrest myeloid humans leukemia metabolized metabolism mice tumors in vivo nuclear neuroblastoma n-Myc n c lipids glucose 0E-12
71220 1,4-DPCA 331830-20-7 ≥98% 2007-06-22 37.829880294659 1-4-dpca 1,4-dihydrophenonthrolin-4-one-3-Carboxylic acid HIF-1.alpha. normoxic HIF-.alpha. prolyl HIF-PH inhibitors collagen fibrosis 4-hydroxylase normoxia hypoxic hypoxia-inducible factor HIF1.alpha. HIF1alpha HIFPH inhibition inhibits 37.829880294659
12700 15-deoxy-Δ12,14-Prostaglandin D2 85235-11-6 ≥95% 29.971454880294 15-deoxy-12-14-prostaglandin-d2 15-deoxy-Δ12,14-PGD2 PPARs prostaglandins peroxisome proliferator-activated receptors 15-deoxy-DELTA12,14-PGD2 15-deoxy-.DELTA.12,14-PGD2 15-deoxy-d12,14-PGD2 leukemia cells cancer 15d-pgd2 29.971454880294
10009742 15-hydroxy Prostaglandin Dehydrogenase Western Ready Control - ≥90% by SDS-PAGE 2007-04-03 36.399861878453 15-hydroxy-prostaglandin-dehydrogenase-western-ready-control 15-hydroxy PGDH blotting blots western WB oxidation enzymes tumors suppression cells proliferation 15pgdh 36.399861878453
10011263 15-Lipoxygenase-2 (human recombinant) - >95% 2008-03-25 24.113627992633 15-lipoxygenase-2-human-recombinant 15-LOX-2; 15-LO-2 arachidonic acids recombinant proteins 15-HETE 15-HpETE active 24.113627992633
34720 15(S)-HETE 54845-95-3 ≥98% 29.942166535122 15-s-hete soybean 15-LOs asthma airway 15-lipoxygenases monohydroxy fatty acids 15S-HETES 15-HETES arachidonic 15(S)-HETEs 15(S)HETEs potato polyunsaturated 15HETEs 29.942166535122
334720 15(S)-HETE-d8 84807-87-4 ≥99% deuterated forms (d1-d8) 48.816648250460 15-s-hete-d8 GC/MS deuterium isotopes 15-HETE-d8 standards 15S-HETE-d8 15(S)HETE-d8 deuterated GC-MS LC/MS LC-MS 15-HETEs 15(S)-HETEs 15S-HETEs 15(S)HETEs hydroxy fatty acids mass spectrometry 15HETE 48.816648250460
534721 15(S)-HETE EIA Kit - 50.025727440147 15-s-hete-eia-kit 15(S)-HETE ELISA Kit solid plates 15(S)-HETEs 15S-HETEs measures kits eias enzyme immunoassays ELISAs 15(S)HETEs 15HETEs assays 50.025727440147
10007251 15(S)-HETE Lipid Maps MS Standard 54845-95-3 ≥98% 2009-02-17 12.386391840204 15-s-hete-lipid-maps-ms-standard soybean 15-LOs asthma airway 15-lipoxygenases monohydroxy fatty acids 15S-HETES 15-HETES arachidonic 15(S)-HETEs 15(S)HETEs potato polyunsaturated MS mass spectrometry standards 15HETE 12.386391840204
15208 16α-hydroxy Estrone New 566-76-7 ≥98% 2013-11-12 22.950768435127 16-hydroxy-estrone 16α-OHE1 steroids endocrinology cancers arthritis autoimmune diseases receptors agonists hormones estrones estradiols estriols E1 E2 E3 E-1 E-2 E-3 Es 1 2 3 one two three hydroxylated OHE1 OHE-1 OHEs interconversion cytochromes P450 CYP450 isoforms CYP1A1 CYP3A5 CYP3A4 Cyp3A7 CYP3A5 breast sulphatized glucuronidated rheumatoid arthritis estrogens metabolites cell proliferation therapy therapies risk factors hydroxyestrone 22.950768435127
11039 17-AAG 75747-14-7 ≥98% 2012-03-21 0.911602209945 17-aag BMS 722782; CP 127374; NSC 330507; Tanespimycin; KOS 953 17AAG 17 AAG inhibitors inhibits inhibition heat shock proteins Hsp90 geldanamycin cancers breasts HER2 hepatotoxicity analogs tumors prostate cells apoptosis NSC330507 NSC-330507 BMS722782 BMS-722782 CP127374 CP-127374 KOS-953 KOS953 0.911602209945
11036 17-DMAG 467214-20-6 ≥98% 2012-03-14 1.409668508287 17-dmag NSC 707545; Alvespimycin; KOS-1022 inhibitors inhibits inhibition heat shock proteins Hsp90 geldanamycin cancers inflammation renal failure tissues tumors NF-κB mice mouse diabetes KOS1022 KOS 1022 NSC-707545 NSC707545 1.409668508287
10009799 17(S)-HDoHE 92693-03-3 ≥98% 2007-03-12 15.335469613260 17-s-hdohe 17(S)-hydroxy Docosahexaenoic Acid resolvins 17-HDHA docosahexaenoic acid COX-2 .omega.-3 w-3 aspirin hydroxylated metabolites oxygenation aspirin-inhibited cyclooxygenase-2 polyhydroxylated TNFa TNF.alpha. IL-1b IL-1.beta. glioma cells COX2 PGHS2 PGHS-2 prostaglandin synthases neurochemistry 17(s)-hdohe 15.335469613260
13812 17β-hydroxy Wortmannin Exclusive 58053-83-1 ≥98% 2010-05-18 14.079069981584 17-hydroxy-wortmannin phosphoinositide 3-kinase PI3K mTOR inhibitors inhibits inhibition inhibitory cancers 17-hydroxywortmannins 17-hydroxy wortmannins hydroxywortmannins PI3-K HWT phosphatidylinositol 14.079069981584
12077 1-hydroxy Vitamin D2 54573-75-0 ≥98% 2012-10-10 14.253615715162 1-hydroxy-vitamin-d2 1-Hydroxyergocalciferol; Hectorol; TSA 840; Doxercalciferol 87649-67-0 125285-48-5 1α-hydroxyergocalciferol 1α-Hydroxyvitamin D2 TSA-840 TSA840 vitamins D bones cancers parathyroid hormones receptors kidney renal diseases prodrug pro-drug pro drugs hyperparathyroidism growth blastomas prostate 14.253615715162
10954 1-NA-PP1 221243-82-9 ≥98% 2011-09-30 49.868011049724 1-na-pp1 1-Naphthyl-PP1; PP1 Analog inhibitors inhibits inhibition kinases mutated analogs sensitive v-Src vSrc c-Fyn cFyn Cdk2 c-Abl cAbl mammalian yeast 1NMPP1 1NA-PP1 cells permeable tyrosine cell-permeable AS Src-family Src I338G v-Src-AS1 49.868011049724
10010093 1-Oleoyl Lysophosphatidic Acid Exclusive 65528-98-5 >95% 2007-08-29 25.946499361766 1-oleoyl-lysophosphatidic-acid 1-Oleoyl LPA; Oleoyl-sn-3-Glycerophosphate LPAS 1-oleoyl-LPAS agonists GPCR G-proteins cell proliferation smooth muscle contraction platelet aggregation reurite retraction 25.946499361766
15108 1-O-Octadecyl-2-O-methyl-sn-glycerol New 83167-59-3 ≥95% 2013-11-06 13.454880294659 1-o-octadecyl-2-o-methyl-sn-glycerol PIA 7; 2-Methyl-1-octadecyl-sn-glycerol ethers lipids ET-18-OCH3 ET 18 OCH3 ET18OCH3 edelfosine phosphotidylinositol analogs PIAs Akts anticancers anti-cancers anti cancers apoptosis octadecyl O methyl sn glycerols metabolites pleckstrin homology domains serine threonine serine/threonine kinases cells endogenous DAGs intracellular signaling signal transductions lipids 13.454880294659
10010094 1-Palmitoyl Lysophosphatidic Acid Exclusive 22002-85-3 ≥98% 2010-11-29 5.755027624309 1-palmitoyl-lysophosphatidic-acid 1-Palmitoyl LPA (free acid) GPCR G-proteins cells proliferation smooth muscles contractions platelets aggregation 5.755027624309
10010290 1-Palmitoyl Lysophosphatidic Acid (sodium salt) Exclusive 17618-08-5 ≥98% 2007-09-05 15.276497237569 1-palmitoyl-lysophosphatidic-acid-sodium-salt 1-Palmitoyl LPA 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate monopalmitoylphosphatidic acid MPPA LPAS GPCRs biological responses 15.276497237569
10009962 2-(14,15-Epoxyeicosatrienoyl) Glycerol 848667-56-1 ≥95% 2008-04-03 31.371104972375 2-14-15-epoxyeicosatrienoyl-glycerol 2-14,15-EG 2-AG CYP450 metabolism mitogens cancers kidneys endocannabinoids cannabinoids cbs synthetic 31.371104972375
10794 22-Oxacalcitriol 103909-75-7 ≥98% 2013-02-20 17.031593001841 22-oxacalcitriol Maxacalcitrol vitamins receptors agonists cancers psoriasis endocrinology nutrition D VDR PTH supress parathyroid hormones synthesis secretions hyperthyroidism renal failure 22 oxacalcitrol analogs calcitrol hypercalcemia inhibits inhibitors inhibition keratinocytes proliferation apoptosis tumors cells 17.031593001841
13373 2',3',5'-triacetyl-5-Azacytidine 10302-78-0 ≥95% 2010-08-05 10.122141946451 2-3-5-triacetyl-5-azacytidine inhibitors inhibits inhibition DNA methyltransferases epigenetics methylation myelodysplastic syndromes cancers prodrugs 5-azacytidine 5-azacitidine azacytidine azacitidine rapid absorption o rally 10.122141946451
10005229 2,3-DCPE (hydrochloride) 1009555-55-8 ≥98% 2006-09-15 13.385874769797 2-3-dcpe-hydrochloride apoptosis Bcl-XL p21 ERK cancers cells cycles proapoptotic in vitro S-phase arrest upregulate activates activation 418788-90-6 13.385874769797
71200 2,4-DPD 41438-38-4 ≥98% 48.618275015347 2-4-dpd 2,4-Diethylpyridine dicarboxylate inhibits inhibition inhibitors proline-hydroxylases P564 HIF-PH HIF-1alpha HIF-1.alpha. alpha-keto glutarate .alpha.-keto a-keto cancer 48.618275015347
10008887 (+)-2,5-epi Goniothalesdiol Exclusive 887927-59-5 ≥98% 2009-03-02 0E-12 -2-5-epi-goniothalesdiol tetrahydrofuran cytotoxic pesticide anticancers drugs antitumor styryl lactone 0E-12
11097 25-hydroxy Cholesterol 2140-46-7 ≥98% 2012-02-08 10.259539878334 25-hydroxy-cholesterol 16505-96-7 oxysterol cholesterol SREBP sterols regulatory elements binding proteins atherosclerosis anticancer apoptosis immunosuppressive Bcl-2 caspases atherosclerosis antitumor tumors LXR-RXR ligands T cells macrophages 10.259539878334
11099 25-hydroxy Cholesterol-d6 88247-69-2 ≥99% deuterated forms (d1-d6) 2012-01-27 4.114120046182 25-hydroxy-cholesterol-d6 deuterated deuterium GC/MS GC-MS LC/MS LC-MS mass spectrometry MS 16505-96-7 oxysterol cholesterol SREBP sterols regulatory elements binding proteins atherosclerosis anticancer apoptosis immunosuppressive Bcl-2 caspases atherosclerosis antitumor tumors LXR-RXR ligands T cells macrophages 4.114120046182
12078 25-hydroxy Vitamin D2 21343-40-8 ≥98% 2012-10-10 38.715739717618 25-hydroxy-vitamin-d2 25-Hydroxyergocalciferol; Ercalcidiol 21343-34-0 29864-49-1 50351-34-3 25-hydroxycalciferol vitamins D bones osteoporosis parathyroid hormones receptors kidneys renal diseases immunity cancers cytochromes P450 isoforms vertebrates agonists 38.715739717618
11879 2-HBA Exclusive 131359-24-5 ≥98% 2012-09-20 5.516849591820 2-hba Bis(2-hydroxybenzylidene)acetone Nrf2 antioxidant ARE Keap1 oxidative stress inflammations cancers curcumin apoptosis Nrf-2 Nrfs Keap-1 Keaps 1 2HBA HBAs inducer enzymes detoxification pathways Michael reaction acceptor cytoprotective NQO1 NQO-1 NQO 5.516849591820
13019 2-Hydroxyestradiol 362-05-0 ≥95% 2009-01-20 5.519005524861 2-hydroxyestradiol NSC 61711; 2-HE2 estradiols steroids metabolism catechol-O-methyltransferase COMT pre-eclampsia preeclampsia angiogenesis cancers anticancer HIF-1α HIF1α 5.519005524861
15271 2-hydroxy Flutamide New 52806-53-8 ≥98% 2013-12-12 92.222222222222 2-hydroxy-flutamide SCH 16423; Hydroxyniphtholide prostates cancers flutamide metabolites CYP1A2 CYP3A4 antiandrogen antagonist androgen receptos hydroxy hydroxy-flutamide active CYPs P450 cytochromes testosterones ARs nuclear in vivo potent dihydrotestosterone steroids hormones Schs Sch-16423 16423 Sch16423 92.222222222222
13021 2-Methoxyestradiol 362-07-2 ≥98% 2009-01-06 65.876609116022 2-methoxyestradiol 2-Hydroxyestradiol 2-methyl ether; 2-ME2; NSC 659853; Panzem estradiol steroids catechol-O-methyltransferase COMT pre-eclampsia preeclampsia angiogenesis cancers anticaner HIF-1α HIF1α 2-methoxyestradiol 65.876609116022
582261 2-Methoxyestradiol EIA Kit - 2010-12-09 166.519650092081 2-methoxyestradiol-eia-kit 2-ME2 ELISA Kit; 2-Hydroxyestradiol 2-methyl ester metabolites estradiols antitumors antiangiogenics breast prostate cancers cardioprotective cytochromes P450 CYP450 P450-dependent hydroxylation 17β-estradiols 2-position O-methylation catechol-O-methyltransferases pre-eclampsia plasma urine urinary markers therapeutics supplements estrogen receptors pregnancy ELISAs EIAs enzymes immunoassays kits competitive quantification measures measurements sample matrices 166.519650092081
11046 2-NBDG 186689-07-6 ≥98% (mixture of α and β) 2012-09-06 100.831887661142 2-nbdg NBD-Glucose fluorescence fluorescent probes glucose uptake cells viability contrast reagents neoplasia cancers diabetes flow cytometry microscopy 213484-93-6 100.831887661142
10010494 2-PCPA (hydrochloride) 1986-47-6 ≥98% 2008-05-09 4.404404821697 2-pcpa-hydrochloride Tranylcypromine; trans-2-Phenylcyclopropylamine 2 PCPA 2PCPA LSD1 histones chromatin nucleosomes post-translational modifications posttranslational methylation demethylation inhibitors inhibits inhibition MAO A B I MAOA MAOB MAOI MAO-A MAO-B MAO-I depression anxiety parkinsons disease epigenetics monoamine oxidases lysine-specific demethylase 4.404404821697
10009651 2-thio-Acetyl MAGE 112014-15-0 ≥97% 2007-02-22 11.963812154696 2-thio-acetyl-mage KIAA1363 cancers colorimetric substrates activity inhibition inhibits inhibitory enzymatic activity 11.963812154696
11881 2-Trifluoromethyl-2'-methoxychalcone Exclusive 1309371-03-6 ≥98% 2012-08-10 3.947853839468 2-trifluoromethyl-2-methoxychalcone Nrf2 antioxidant response elements ARE oxidative stress inflammation Keap1 activator anti-cancer anti-inflammatory GCLM NQO1 activators activate active Nrf-2 Nrfs 2 Keap-1 Keaps 1 anticancer antiinflammatory in vitro bronchial epithelial cells Beas-2B Beas2B Beas 2B small intestines 3.947853839468
10004185 3,4',5-Trismethoxybenzophenone Exclusive 94709-12-3 ≥95% 2004-07-21 16.002504604051 3-4-5-trismethoxybenzophenone antimitotics antimitosis resveratrol analogs phenolic antioxidants antiproliferative antiproliferatory inhibits inhibition inhibitors cell growth 16.002504604051
10727 3,5-dimethyl PIT-1 701947-53-7 ≥98% 2011-05-25 7.477375690607 3-5-dimethyl-pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domain cancers inhibitors Akts PDK1 PTENs proteins binding inhibits inhibited inhibition DM-PIT-1 7.477375690607
10397 3-amino Benzamide 3544-24-9 ≥98% 2011-10-07 1.070404380375 3-amino-benzamide 3-(Aminocarbonyl) Aniline; 3-Carboxamidoaniline poly(ADP-ribose) polymerases PARPs DNA repairs DNA strands breaks apoptosis inflammation atherosclerosis neruogenesis cancers angiogenesis signaling cellular responses inhibits inhibitor inhibition telomere shortening shortens stimulates mediated mediates PARP-mediated 1.070404380375
15419 3-AP New 143621-35-6 ≥95% 2014-01-22 99.105463474524 3-ap NSC 663249; Triapine™; 3-Aminopyridine-2-Carboxyaldehyde Thiosemicarbazone 236392-​56-​6 ribonucleotide reductase inhibitors inhibits inhibitions DNA synthesis cancers anti-tumors tumors anti antitumor iron chelator R2/p53R2 subunits ER stress UPR unfolded proteins response apoptosis oxidative injury 3AP 3 APs aminopyridine carboxyaldehyde thiosemicarbazone in vitro NSCs 663249 NSC663249 NSC-663249 OCX-191 OCX191 OCXs 191 Pans pan-811 811 pan811 99.105463474524
13574 3-bromo-5-phenyl Salicylic Acid Exclusive 4906-68-7 ≥95% 2010-08-10 19.121535911602 3-bromo-5-phenyl-salicylic-acid NSC 109116 Aldo-keto reductases AKR, oxidoreductases hydroxysteroid dehydrogenases HSDs 20α-HSD progesterones cancers steroids brain functions AKR1C1 AKR1C2 AKR1C3 AKR1C4 endothelial cells 19.121535911602
13828 3-Deazaneplanocin A 102052-95-9 ≥97% 2011-02-18 139.064721301411 3-deazaneplanocin-a NSC 617989; DZNep EZH2 KMT6 methyltransferases histones cancer epigenetics panobinostat 3deazaneplanocin 3-cyclopentene-1,2-diol deriv Adenosine Adenocard 139.064721301411
11102 3-Deazaneplanocin A (hydrochloride) 120964-45-6 ≥98% 2012-06-22 41.312163337864 3-deazaneplanocin-a-hydrochloride 2,3-DMMC monohydrochlorides HCl 934968-81-7 lysines methyltransferases EZH2 KMT6 polycomb repressive complexes 2 catalyzes trimethylation 27 histones H3 proliferations aggressive cells growth neoplastic cyclopentyl analogs 3-deazaadenosine inhibitors inhibits inhibition S-adenosyl-L-homocysteines hydrolases levels cultured human acute myeloid leukemias AML HL-60 OCI-AML3 primary expression cell-cycle regulators p21 p27 FBXO32 cycles arrests apoptosis death regulated pan-histones deacetylases panobinostat antileukemic effects synergistically mice mouse cancers chromatins research epigenetics modifications HDACs SAM hydrolases HL60 HL 60 OCI AML3 p-21 p 21 p-27 27 FBOX-32 FBOX 32 41.312163337864
13242 3-Methyladenine 5142-23-4 ≥98% 2012-08-09 45.595552486188 3-methyladenine NSC 66389; 3-MA NSC66389 NSC-66389 autophagy lysosome mTOR phosphoinositide 3-kinases PI3K key regulator inhibitors proteins degradation class I class II class III metastasis inhibits inhibitions 3MA 3 Mas methyl-adenine methyl adenine autophagic cytoplasmic lysosome fibrosarcoma HT1080 HT-1080 HTs 1080 cells 45.595552486188
13265 4-hydroxy Nonenal Alkyne Exclusive 1011268-23-7 ≥98% 2010-06-16 108.699742173112 4-hydroxy-nonenal-alkyne Click Tag™ 4-HNE alkyne lipids peroxidation inflammation neurodegeneration atherosclerosis diabetes cancers click chemistry Click Tag™ 4-HNEs alkynes IT 108.699742173112
10495 4-iodo-SAHA 1219807-87-0 ≥98% 2011-01-10 8.652999210733 4-iodo-saha anti-cancers HDACs inhibitors anti-proliferation 4-Hydroxy-5-iodo-3-nitrophenyl)acetyl 4-Hydroxy-3-iodo-5-nitrophenyl)acetyl 5-Iodo-4-hydroxy-3-nitrophenacetyl 5 Iodo 4 hydroxy 3 nitrophenacetyl Nitrohydroxyiodophenylacetate Hydroxyiodonitrophenylacetate Hapten NIP Acetyl Acetyl Hapten NIP NIP Acetyl Hapten NIP-Hapten NIP Hapten 8.652999210733
9001510 4-methyl Erlotinib New 1346601-52-2 ≥95% 2013-12-09 134.046476098967 4-methyl-erlotinib receptors biochemistry inhibitors cancers signals transductions inhibits inhibitions methylated analogs tyrosine kinase epidermal growth factors EGFRs binds binders bindings hydrophobic phenyls methyl 4 four NSCs 718781 NSC-718781 NSC718781 CPs 358774 CP-358774 CP358774 134.046476098967
10185 4-oxo-2-Nonenal Exclusive 103560-62-9 >98% 2004-01-21 41.968204419889 4-oxo-2-nonenal 4-ONE ROS Alkenals aldehydes free radicals peroxidation lipid autoxidation reactive oxygen species 41.968204419889
10004174 4-oxo 2-Nonenal-d3 Exclusive 1313400-91-7 ≥99% deuterated forms (d1-d3) 2004-03-10 26.229723756905 4-oxo-2-nonenal-d3 4-ONE-d3 ROS Alkenals aldehydes free radicals peroxidation lipid autoxidation reactive oxygen species 4-OH-2-nonenal-d3 4-hydroxy2nonenald3 internal standards mass spectrometry GC/MS LC/MS gc-ms ic-ms deuterium deuterateds 26.229723756905
10011049 4-phenyl-5-methyl-1,2,3-Thiadiazole 64273-28-5 ≥98% 2009-03-14 0.604419889503 4-phenyl-5-methyl-1-2-3-thiadiazole NSC 358739 cytochrome P450 CYP450 CYP2B4 CYP2E1 CYP1A2 inhibitors inhibits inhibition thiadiazoles fungicide herbicide plant growth regulator 0.604419889503
9001902 5-Aminolevulinic Acid (hydrochloride) New 5451-09-2 ≥98% 2014-03-05 0E-12 5-aminolevulinic-acid-hydrochloride 5-ALA; δ-Aminolevulinic Acid 106-60-5 cancers fluorescence fluorescent probes ALAs 5ALA porphyrins hemes ROS reactive oxygen species light photodynamic dermatological cancers diseases levulan kerastick 5-amino-4-oxopentanoic 0E-12
11164 5-Azacytidine 320-67-2 ≥95% 2012-02-16 13.205709023940 5-azacytidine Ladakamycin; 5-AzaC; NSC 103-627; U 18496; WR 183027; NSC 102816; Mylosar; Antibiotic U 18496 52934-49-3 292869-98-8 ledakamycin azacitidine 5-azacitidine 5 azacitidine 5 azacytidine 5-AZCR 5-AZC 5-AC methyltransferases histones cancers epigenetics cytidine inhibitors DNA RNA inhibits inhibition diseases cells 13.205709023940
13379 5-bromo-3-phenyl Salicylic Acid 99514-99-5 ≥95% 2010-08-10 19.121535911602 5-bromo-3-phenyl-salicylic-acid Aldo-keto reductases AKR oxidoreductases hydroxysteroid dehydrogenases HSD 20α-HSD progesterone cancers steroids brain functions AKR1C1 AKR1C2 AKR1C3 AKR1C4 endothelial cells 19.121535911602
11635 5-Fluorocytosine 2022-85-7 ≥95% 2012-04-16 4.379760589318 5-fluorocytosine NSC 103805; 5-FC; Ancotil; Ancobon; Ro 2-9915 flucytosin fluocytosine fluorocytosine alcobon ancotyl prodrugs 5-fluorouracil cytotoxic inhibitors inhibits inhibition Candida species Cryptococcus neoformans viral infection cancers cytosine deaminase 5 fluorocytosine fluorine drugs DNA proteins sybthesis cells CT26 Tu-2449 tumors flucytosine 4.379760589318
13856 5-Nitroso-8-quinolinol 3565-26-2 ≥95% 2012-10-25 13.525276243094 5-nitroso-8-quinolinol Hydron III; NSC 3852 5-nitrosooxine NSC3852 NSC-3852 hydron 3 HDACs inhibitors antitumors oxidative stress ROS apoptosis antiproliferative cancers cells differentiation Toxoplasma gondii Plasmodium falciparum inhibits inhibitions Zn2+ chelation motif SAHA MCF-7 MCF7 tumors agents 13.525276243094
10009315 6-Aminonicotinamide 329-89-5 ≥98% 2008-11-21 5.682320441989 6-aminonicotinamide SR 4388; NSC 21206; 6-AN inhibitors inhibits inhibition 6-phosphoguconate dehydrogenase cancers ATPs oxidative injury neurodegeneration cardiovascular 5.682320441989
15774 6-Thioguanine New 154-42-7 ≥95% 2014-04-16 0E-12 6-thioguanine 6-TG; NSC 752; NSC 76504 611-​67-​6 1125-​65-​1 1832-​72-​0 5632-​51-​9 153981-​50-​1 158476-​00-​7 thiopurines antimetabolites anti metabolites anti-metabolites chemotherapy purines analogs DNA damages double strands breaks cancers cytotoxicity thio purines cytosines methylation methyltransferases leukemia tumors BRCA2 BRCA-2 BRCAs 2 two mutated epigenetics thioguanine thioguanine six 6 lanvis S6G tabloid TGs thio-guanine NSCs 752 76504 NSC752 NSC76504 NSC-752 NSC-76504 genes regulations chemotherapeutics BRCA2-mutated repairs 2-Amino-6-mercaptopurine Tioguanin Tioguanine 0E-12
10009027 6α-hydroxy Paclitaxel 153212-75-0 ≥95% 2013-10-10 13.198026222825 6-hydroxy-paclitaxel 153720-55-9 172228-55-6 19027 cancers metabolism cytochromes P450 CYP450 metabolites paclitaxels anticancers anti-cancers anti isoforms CYP2C8 drugs fluvastatin diets dietary components genetic genes polymorphisms taxols 6α 6alpha 6.alpha. 6a 6 six alpha α a .alpha. 10927 13.198026222825
10009856 7-AAD Cell Viability Assay Kit - 2008-10-29 55.762720823954 7-aad-cell-viability-assay-kit 7-Amino Actinomycin D Cell Viability Kit kits 7AAD measurement cells fixation blocking cytoxicity effects environmental toxins drug fluorescence fluorescent cell-based assays cell based assay cba 55.762720823954
600120 7-AAD/CFSE Cell-Mediated Cytotoxicity Assay Kit - 2009-08-05 48.814617205998 7-aad-cfse-cell-mediated-cytotoxicity-assay-kit 7-Amino Actinomycin D/5-(6)-Carboxyfluorescein Diacetate Succinimidyl Ester 7-amino actinomycin D/5-(6)-carboxyfluorescein diacetates succinimidyls esters assays kits measuring measurement kits 5-(6) 5,6 5-6 7AAD cells cytoxicity cell-based cba cytolysis target effector T lymphocytes NK natural killer autoimmune systems pathological cancers multiple sclerosis granule exocytosis pathways Fas diseases graft host 51chromium 51Cr green fluorescent fluorescence probes red propidium iodide dead effector carboxyfluorescein succinimidyl esters dyes damaged DNA deoxyribonucleic acids quantify quantification single staining 48.814617205998
89300 8-hydroxy Guanosine 3868-31-3 ≥98% 13.023627992633 8-hydroxy-guanosine oxidative injury RNA stress damage 7,8-dihydro-8-oxo-guanosine markers inhibitors growth 29851-​58-​9 448192-​32-​3 13.023627992633
15148 Abiraterone Acetate New 154229-18-2 ≥98% 2013-11-06 215.310802334298 abiraterone-acetate Zytiga®; CB-7630 inhibitors inhibits inhibitions cancers steroids hormones cytochromes P450 endocrinology CYP17A1 CYPs CYP450 CYP-17A1 17A1 blocks blockage blocking inhibiting 17α-hydroxylases 17alpha-hydroxylases 17.alpha.-hydroxylases hydroxylases 17 20 lyases activity activities reactions synthesis androgens estrogens glucocorticoids mineralocorticoids mice mouse men human testosterones plasma luteinizing hormones LH radiographic progression-free free progression survival metastatic castration-resistant castration resistant prostates CB7630 CBs 7630 CB-7630 215.310802334298
11500 ABT-263 New 923564-51-6 ≥98% 2013-12-19 85.733083399106 abt-263 Navitoclax; A-855071 inhibitors apoptosis cancers intracellular signaling ABTs ABT263 263 potent anti-apoptotic antiapoptotic anti apoptotic Bcl-2 Bcl2 Bcls 2 two proteins BH3 BH-3 BHs 3 three homology tumors therapeutics therapy chemotherapeutics cells 1000696-69-4 As 855071 A855071 A-855071 Bim regression .beta. b β catenin .beta.-catenin b-catenin β-catenin Bcl-XL XL BCL-w w 85.733083399106
11501 ABT-737 New 852808-04-9 ≥98% 2014-01-02 95.941416732439 abt-737 inhibitors apoptosis cancers intracellular signaling inhibits inhibitions anti-apoptotic antiapoptotic anti apoptotic Bcl-2 Bcl2 Bcl 2 two ABTs 737 ABT737 potent cell-permeable cells permeable mimetics BH3 BH-3 BHs 3 three homology Bcl-XL BclXL XL Bcl-w Bclw w proteins tumors therapeutics radiation 95.941416732439
13653 ABT-869 796967-16-3 ≥98% 2010-12-09 5.756795580110 abt-869 Linifanib inhibitors RTK tyrosine kinases VEGF PDGF cancers KDR Flt1 Flt3 Flt4 CSF-1R KIT acute myeloid leukemia antiproliferative anti-proliferative ABT 869 ABT869 Indazoles 5.756795580110
11505 ABT-888 (hydrochloride) New 912445-05-7 ≥98% 2014-01-03 80.089062618125 abt-888-hydrochloride Veliparib inhibitors DNA damages repairs cancers apoptosis autophagy inhibits inhibitions ABTs ABT888 888 HCl poly(ADP-ribose) polymerases PARPs oral orally bioavailable PARP1 PARP2 PARPs PARP-1 PARP-2 1 2 one two breaks radiation alkylation chemotherapies cancers cells 912444-00-9 chemotherapy 80.089062618125
10008051 Acid Phosphatase Colorimetric Assay Kit - 2006-09-20 18.010607734807 acid-phosphatase-colorimetric-assay-kit AP aps hydrolase eznymes prostate pap tartrate resistant assays 18.010607734807
14003 Acivicin 42228-92-2 ≥98% 2012-11-27 6.573480662983 acivicin NSC 163501; Antibiotic AT 125; U 42126 AT125 AT-125 NSC163501 NSC-163501 U42126 U-42126 glutamines glutamine-dependent amidotransferases inhibitors nucleotides anthranilate synthases glutamates synthase γ-glutamyl transpeptidase glutathione metabolism anti-tumors anti-cancers analogs inhibits inhibitions amidotransferases biosynthesis anti-tumorigenic antitumorigenics 6.573480662983
11421 Actinomycin D 50-76-0 ≥98% 2012-10-03 6.007734806630 actinomycin-d Cosmegen; Dactinomycin; NCI C04682; Oncostatin K; Meractinomycin; NSC 3053 1402-51-3 1402-58-0 C1 AIV I1 IV X1 A IV 7 AD actinomycindioic D acid dilactone chounghwamycin B dactinomycin D lyovac NCIC04682 NCI-C04682 NSC3053 NSC-3053 antibiotics DNAs transcriptions RNAs synthesis anticancers cells deaths antitumors anti-cancers anti cancers anti-tumors anti tumors agents fluorescent derivative 7-aminoactinomycin 7-AAD AAD 7AAD markers actinomycin-d 6.007734806630
13975 AD57 (hydrochloride) Exclusive - ≥98% 2012-12-18 0E-12 ad57-hydrochloride 1093380-42-7 polypharmacological cancers therapeutics inhibitors inhibits inhibitions invasions proliferation growth metabolism tyrosines kinases receptors serine/threonine AD-57 ADs 57 HCl drosophila Ret Src Raf S6K therapeutic 0E-12
9001421 AD80 (hydrochloride) Exclusive New - ≥98% 2014-04-03 0E-12 ad80-hydrochloride 1384071-99-1 cancers inhibitors inhibits inhibitions kinases proteins signals transductions Ads 80 AD-80 HCl MEN2B multiple endocrine neoplasia type 2B pote dRet Raf Src S6 cells tumor growth Ret rearranged during transfection dRetMEN2B AD80 mTOR 0E-12
10006908 Adipogenesis Assay Kit - 2006-08-18 76.805303867403 adipogenesis-assay-kit obese obesity cells cycle differentiation inhibits inhibitors inhibition adipocytes cancers origin 3T3-L1 model drug screening adipokines endocrinology cell-based assays cell based assay cba 76.805303867403
10009381 Adipolysis Assay Kit - 2007-07-30 38.619878453038 adipolysis-assay-kit obese obesity cells cycle differentiation inhibits inhibitors inhibition adipocytes cancers origin 3T3-L1 model drug screening adipokines lipolysis 3T3L1 kits assays FFA adipocytes endocrinology cell-based assay cell based assay cba 38.619878453038
11293 Aflatoxin B1 1162-65-8 ≥98% 2012-01-30 20.087721652197 aflatoxin-b1 AFB1; NSC 529592; HSDB 3453 11003-08-0 13214-11-4 27261-02-5 toxicology pathogens mycotoxins Aspergillus cancers HCC hepatocellular carcinomas p53 DNA adduct mold carcinogenic metabolism liver epoxide tumoors suppression genes food contaminant contamination D03.438.150.119.075 D03.830.219.119.07 NSC-529592 HSDB-3453 20.087721652197
11294 Aflatoxin B2 7220-81-7 ≥98% 2012-01-30 16.189379110760 aflatoxin-b2 Dihydroaflatoxin B1 dihydroaflatoxine B1 toxicology pathogens mycotoxins Aspergillus cancers HCC hepatocellular carcinoma p53 DNA adduct molds carcinogenic carcinogens liver epoxide tumors genes food contamination contaminants pathogens 16.189379110760
10010129 AG-041R Exclusive 199800-49-2 ≥98% 2008-12-16 15.011412938870 ag-041r CCKs gastrin receptors antagonist cancers proliferations apoptosis NS-398 NS398 NS 398 15.011412938870
14833 AG-1024 65678-07-1 ≥98% 2013-08-22 3.408018472119 ag-1024 AGS 200; Tyrphostin AG-1024 tyrphostin inhibitors inhibits inhibition AG1024 AGs 1024 IGF1 IGFs 1 one IGF-1 receptors proteins tyrosines kinases IGF-1R IGF1R 1R insulin-like insulin like growth factors cancers apoptosis proliferation stimulated cellular autophosphorylation apoptosis humans breasts MCF-7 MCF7 MCF 7 seven autocrine prostates DU145 DU-145 DU 145 AGS200 AGS-200 AGS 200 receptors biochemistry signals transduction IGF-1 insulin-stimulated stimulated stimulates 3.408018472119
14529 AG-1295 71897-07-9 ≥98% 2013-05-24 3.519443682052 ag-1295 NSC 380341; Tyrphostin AG-1295 biochemistry cardiology cancers Tyrphostins inhibitors inhibits inhibitions PDGFs receptors kinases proteins tyrosines PTKs anti proliferatives proliferations hyperactivity blocks blockers AGs 1295 AG-1295 AG1295 NSCs 380341 NSC-380341 NSC380341 platelet-derived growth factors platelets derived atherosclerosis restenosis pulmonary fibrosis gliomas quinoxaline-types quinoxalines types Swiss 3T3 cells PDGF-stimulated DNA synthesis PDGFs stimulated EGFs 3.519443682052
10010592 AG-1296 146535-11-7 >98% 2008-05-09 6.811987034396 ag-1296 Tyrphostin AG-1296 tyrphostins AG1296 PDGFR PTK SCF inhibitors inhibits inhibition receptors kinases proteins platelet-derived platelet derived growth factors in vitro cancer glioma athrosclerosis restenosis AG1296 AG 1296 6.811987034396
10010244 AG-1478 153436-53-4 ≥98% 2008-04-22 10.911043021236 ag-1478 Tyrphostin AG-1478; NSC 693255 NSC 693255 EGFR PTK inhibitors inhibits inhibition kinases receptors cancers antitumor leioyoma myometrium 175178-82-2 AG1478 AG 1478 t4182 10010244-t4182 10.911043021236
10010248 AG-17 10537-47-0 ≥98% 2007-09-18 3.429770018076 ag-17 Tyrphostin 9; Malonoben; Tyrphostin AG-17; SF 6847; GCP 5126; RG-50872; NSC 242557 proteins tyrosine kinases PTK inhibitors inhibits antiproliferative epidermal growth factor EGF receptors proliferations carcinomas AG17 AG 17 SF6847 SF-6847 GCP-5126 GCP5126 tyrphostin a9 3.429770018076
10010300 AG-18 118409-57-7 >98% 2007-12-20 5.537934974667 ag-18 RG-50858; TX 825; Tyrphostin 23; Tyrphostin AG-18; RG-50810 proteins tyrosines kinases PTKs inhibitors inhibition inhibits antiproliferative epidermal growth factors EGF receptors proliferations carcinoma cancers epidermoid cell lines A431 AG18 AG 18 A23 A-23 A23 RG50810 RG 50810 RG50858 RG 50858 TX-825 TX825 5.537934974667
10010315 AG-183 122520-90-5 ≥98% 2007-09-07 1.822689003742 ag-183 Tyrphostin 51 proteins tyrosine kinases PTKs inhibitors inhibition inhibits inhibition antiproliferative epidermal growth factors EGFs receptors proliferation carcinomas cancers epidermoid AG183 AG 183 1.822689003742
10010314 AG-213 122520-86-9 ≥97% 2008-02-05 5.884266678547 ag-213 Tyrphostin 47; Tyrphostin AG-213 protein tyrosine kinases PTKs inhibitors inhibits inhibition antiproliferative epidermal growth factors EGFs receptors proliferation carcinomas A431 epidermal AG213 Ag 213 118409-60-2 5.884266678547
10010568 AG-370 134036-53-6 >95% (cis/trans mixture) 2009-01-09 1.380481482801 ag-370 NSC 651712 PTK inhibitor tyrphostin tyrosine PDGF receptor kinase EGF receptor antiproliferative 1.380481482801
10010311 AG-490 133550-30-8 ≥98% 2007-12-01 24.410139465632 ag-490 PTK tyrosine kinase inhibitors inhibition inhibits antiproliferatives tyrphostins leukemia Jak-2 Jak2 AG490 134036-52-5 B 42 B-42 B42 24.410139465632
10010242 AG-494 133550-35-3 ≥98% 2008-02-08 3.031698778497 ag-494 protein tyrosine kinases PTKs inhibitors inhibits inhibition antiproliferative RG-13022 epidermal growth factors EGFs receptrors cancers proliferation 3.031698778497
15568 AG-538 New 133550-18-2 ≥98% 2014-04-14 0E-12 ag-538 tyrosine kinases inhibitors inhibits inhibitions insulin like factors 1 one insulin-like growth factor-1 receptors IGF-1 IGF-R Akt PKB Erk2 cancers IGFs IGF1 IGF1R 1R IGF-1R AGs 538 AG538 substrates competitive breast cells lines autophosphorylation signals transductions cancers 0E-12
10010312 AG-82 118409-58-8 ≥95% 2008-03-14 2.968365754767 ag-82 Tyrphostin 25; RG-50875; NSC 676484; Tyrphostin AG-82 proteins tyrosines kinases PTKs inhibitors inhibits inhibition antiproliferative epidermal growth factors EGFs receptors proliferation carcinomas blockers A431 AG82 AG 82 RG-50875 RG50875 A25 A-25 2.968365754767
10010243 AG-825 149092-50-2 ≥98% 2008-01-24 5.582954843165 ag-825 Tyrphostin AG-825 Her-2 Her-2/neu erbB tyrosine kinases EGF EGFR cancers anti-cancer prostate breast signal transduction inhibitors inhibition inhibits AG825 AG 825 5.582954843165
10793 AG-879 148741-30-4 ≥95% 2011-05-06 4.864360125942 ag-879 Tyrphostin AG-879 PTKs inhibitors tyrphostins tyrosine kinases antiproliferative NGF TrkA ErbB2 FLK-1 AG879 AG 879 inhibited inhibition 4.864360125942
10010313 AG-99 122520-85-8 ≥98% 2007-12-19 1.708451859671 ag-99 Tyrphostin 46 protein tyrosine kinase PTKs inhibitor inhibits inhibition antiproliferatives epidermal growth factors EGFs receptors proliferation carcinoma cancers blochers EGF-dependent A431 cell lines AG99 AG 99 1.708451859671
14624 AGI-5198 1355326-35-0 ≥98% 2013-06-14 15.114129834253 agi-5198 IDH-C35 IDHC35 IDH C35 inhibitors inhibits inhibitions isocitrates dehydrogenases IDH1 IDH-1 IDH 1 one α-ketoglutarate 2OG 2 OG two 2-OG gliomas antitumor anti tumors anti-tumors 2-hydroxyglutarate hydroxyglutarates HGs 2-HG R132H mutants histones demethylations gliogenesis AGI5198 AGI 5198 potent selectives R132C in vitro TS603 TS-603 xenografts H3K9me3 genes gliogenic differentiations cancers enzymes activity actives metabolisms NADs NADPs NAD-dependent NADP-dependent dependents tricarboxylic acids cycles catalyzes oxidatives decarboxylations alpha ketoglutarates alpha-ketoglutarate carbons dioxides IDH1 IDH2 mutated mutations maps arginines residues catalytic pockets gains of functions NADPH-dependent NADPHs conversion AGI-5198 wild-type wilds types cells lines growths treatments periods induces expressions 15.114129834253
14639 AGI-6780 1432660-47-3 ≥98% 2013-07-19 16.622762430939 agi-6780 IDH inhibitors IDH2 isocitrate dehydrogenase α-ketoglutarate 2-OG glioma anti-tumor 2-hydroxyglutarate 2-HG IDH1 R140Q mutant AML leukemias differentiations therapy cancers therapies AGI6780 AGIs 6780 AGI 6780 potent selective inhibits inhibitions two IDH-2 2 HGs U87 U-87 Us 87 TF-1 TF1 TFs 1 one cells growths suppresses slineages macrophages franulocytic 16.622762430939
13145 AGK2 304896-28-4 ≥98% 2009-10-22 14.483729281767 agk2 sirtuins SIRT2 histones deacetylase HDAC cells cycle progression tumorigenesis cancers SIRT1 SIRT3 dopamine neurons α-synuclein Parkinson's diseases neurodegeneration 14.483729281767
19023 AH 23848 (calcium salt, hydrate) - ≥90% 2009-02-26 57.021922651934 ah-23848-calcium-salt-hydrate AH23848B AH 23848 TXBs thromboxane PGEs PGE2 receptors prostanoids TPs EP4 antagonist blockers inhibitors inhibits inhibition TXA2 platelets smooth muscle bronchial U-46619 U46619 fibroblasts cancers metastasis 81739-45-9 AH-23848 57.021922651934
10010241 AICAR 2627-69-2 ≥98% 2008-02-25 121.758501381215 aicar AICA Riboside; Acadesine; NSC 105823 AMPK lipids metabolism glucose fatty acids sterol HMG-CoA reductases inflammation cytokine iNOS COX-2 MnSOD glia macrophages TNF-.alpha. IL-1.beta. IL-6 aminoimidazole carboxamide ribonucleotide 121.758501381215
160773 AIF Polyclonal Antibody - 0E-12 aif-polyclonal-antibody Apoptosis-Inducing Factor; Programmed Cell Death Protein 8 apoptosis antibodies western blots blotting WB antisera antiserum factors cancers immunoblotting 0E-12
14004 AK-7 420831-40-9 ≥95% 2012-11-12 2.366022099448 ak-7 inhibitors sirtuins neurodegeneration cancers diabetes cholesterol Alzheimer’s diseases huntingtin Huntington’s Parkinson’s neurosciences AK7 AK 7 cell-permeable cells brain-permeable brains inhibits inhibitions SIRT-2 SIRTs 2.366022099448
13733 Akt1 (Phospho-Ser473) Monoclonal Antibody (Clone 104A282) - 2010-01-11 1.119605367008 akt1-phospho-ser473-monoclonal-antibody-clone-104a282 antibodies Akts PKBs peptides Akt-1 Akt 1 protein kinase B serine threonine western blots blotting immunoblotting WB IP Immunoprecipitation IP 1.119605367008
13732 Akt1 Polyclonal Antibody - 2010-01-11 1.119605367008 akt1-polyclonal-antibody antibodies Akts PKBs peptides Akt-1 Akt 1 protein kinase B serine threonine western blots blotting immunoblotting WB 1.119605367008
13735 Akt2/3 Polyclonal Antibody - 2010-01-12 1.119605367008 akt2-3-polyclonal-antibody Akt-2 Akt 2 PKB proteins kinase B serine threonine signaling PI3-kinase cancers Western blots blotting immunoblotting WB Akt-3 Akt 3 2-3 1.119605367008
13734 Akt2 Monoclonal Antibody (Clone 95C567.1.2) - 2010-01-12 1.119605367008 akt2-monoclonal-antibody-clone-95c567-1-2 Akt-2 Akt 2 PKB proteins kinase B serine threonine signaling PI#-kinase cancers Western blots blotting immunoblotting WB 1.119605367008
13736 Akt3 Monoclonal Antibody (Clone 66C1247.1) - 2010-01-19 1.119605367008 akt3-monoclonal-antibody-clone-66c1247-1 Akt-3 Akt 3 western blot blotting immunoblotting WB Akts protein kinase B PKB serin threonine signaling proteins 1.119605367008
14870 Akt Inhibitor VIII 612847-09-3 ≥98% 2013-10-24 18.721013600080 akt-inhibitor-viii inhibitors cancers signals transductions angiogenesis apoptosis kinases Akts VIII potent allosteric inhibits inhibitions Akt-1 Akt-2 Akt1 Akt2 1 one 2 two serine-threonine serines threonines cells permeable blocking blocks blockage insulin regulation forkhead box 01 FOXO1 hepatoma Akti-1/2 ½ Akti proteins 18.721013600080
14863 Akt Inhibitor X 925681-41-0 ≥95% 2013-08-14 32.092950756447 akt-inhibitor-x 201788-90-1 phenoxazines Akts mTOR p70S6 kinases S6 ribosomal proteins apoptosis cells signalings inhibitors inhibits inhibitions permeable derivatives suppresses suppressions insulin-like insulin liked growth factors 1 one IGFs 1 IGF-1 IGF1 stimulated blocks blocking Rh1 Rh-1 Rhs Rh-18 Rh18 Rh-30 Rh30 p70S6 kinases S6 S-6 proteins apoptosis intracellular signals transduction 32.092950756447
700800 Aldehyde Dehydrogenase Activity Assay Kit - 2013-04-08 53.586179558011 aldehyde-dehydrogenase-activity-assay-kit ALDH kits assays measures measurements ALDHs enzymes oxidizes oxidations endogenous exogenous aldehydes dehydrogenases carboxylic acids metabolisms amino carbohydrates lipids biogenic amines vitamins steroids humans superfamily isozymes physiological toxicological ALDH1A subfamily embryogenesis developments mediates mediating retinoic signaling signals signalling ALDH2 acetaldehydes cells tissues alcohol ingestions carcinogenesis ALDH1A1 ALDH3A1 lens corneal crystallins cellular defenses mechanisms UV ultraviolet radiations radiation-induced damages ocular cancers stems pharmacologicals inhibits inhibitors inhibitions anticancers anti anti-cancers oxazaphophorines drugs diseases Type II 2 hyperprolinemia Sjogrens Sjogren-Larsson Syndromes Parkinson's cardiac hearts hyperammonemia fluoroescence-based methods fluorescent homogenates cultures samples purified preparations fluorometrics 53.586179558011
10009350 Aldehyde Reactive Probe (trifluoroacetate salt) 627090-10-2 ≥98% 2008-08-26 15.311325966850 aldehyde-reactive-probe-trifluoroacetate-salt ARP; O-(Biotinylcarbazoylmethyl) Hydroxylamine DNA damages AP sites synthesis mutations ROS biotin oxidative stress detection detecting 139585-03-8 15.311325966850
13876 Alexidine (hydrochloride) 1715-30-6 ≥98% 2013-01-16 0.220994475138 alexidine-hydrochloride 22573-93-9 217969-93-2 antibiotics bacteria infectious diseases inhibitors cancers inhibits inhibitions biguanide bis(biguanide) antiseptic mouthwash plaque microorganisms lipopolysaccharide lipoteichoic final phospholipase B PTPMT1 0.220994475138
14002 (+)-Alliin 556-27-4 ≥98% 2012-11-27 6.566850828729 -alliin S-Allyl-L-cysteine sulfoxide 23358-38-5 S-Allyl-L-cysteine-(+)-sulfoxide cysteine garlic alliinase allicin anti-cancers anti-microbial anti-hypertensive cardioprotective anti-oxidant squalene monooxygenase inhibitors aromas flavors inhibits inhibitions anticancer cancers antimicrobial microbial antihypertensive hypertensive antioxidant oxidant anti cholesterol biosynthesis sulfoxide 6.566850828729
14001 (±)-Alliin 17795-26-5 ≥98% 2012-11-26 3.331767955801 -alliin (±)-Allyl-L-cysteine sulfoxide S-Allyl-L-cysteine sulfoxide SAllylcysteine cysteine garlic alliinase allicin anti-cancers anti-microbial anti-hypertensive cardioprotective anti-oxidant squalene monooxygenase inhibitors aromas flavors inhibits inhibitions anticancer cancers antimicrobial microbial antihypertensive hypertensive antioxidant oxidant anti cholesterol biosynthesis 3.331767955801
14428 Alsterpaullone 237430-03-4 ≥98% 2013-04-04 8.794173606487 alsterpaullone NSC 705701; 9-Nitropaullone 959569-16-5 proteins kinases inhibitors inhibits inhibitions cells cycles cancers NSC705701 NSC-705701 kenpaullone cyclins cyclin-dependent glycogens synthases 3 GSK3 Cdk1/cyclin B Cdk2/cyclin A Cdk2/cyclin E Cdk5/p25 GSK-3α/β Wnt signaling proliferatins paullones CDKs GSKs signals signalling Alzheimer's diseases expressions antitumors anti tumors anti-tumors apoptosis inducers induction ATP-competitive adenosines triphosphates cytosolics degradations β-catenin b-catenin beta-catenin .beta.-catenin canonical pathways tau phosphorylations 8.794173606487
15261 AM580 New 102121-60-8 ≥98% 2014-03-26 0E-12 am580 Ro 40-6055; CD336; NSC 608001 synthetic retinoids retinobenzoic acids vitamin A retinoic acid RARs RARα receptor agonist nuclear differentiation induced pluripotent stem cells iPCS anticancer antiproliferation AMs 580 AM-580 CDs 336 CD-336 NSCs 608001 NSC608001 NSC-608001 Ros 40-6055 406055 40 6055 Ro-40-6055 Ro-406055 Ro-40 Ro40-6055 Ro406055 selective α .alpha. alpha a RARalpha RAR.alpha. RARa RARβ β b beta .beta. RARb RARbeta RAR.beta. RARg RARgamma RAR.gamma. gamma .gamma. g RARγ γ binding binds GSK3β GSK3b GSK3.beta. GSK3beta CHIR99021 CHIR 99021 induces humans immediates mesoderm inhibits inhibitors inhibitions tumors survival signaling pathways inducing apoptosis 0E-12
71770 AM80 New 94497-51-5 ≥98% 2014-03-26 0E-12 am80 NSC 608000; Amnolake; Retinobenzoic Acid; Tamibarotene synthetic retinoids retinobenzoic acids vitamin A retinoic RARs RARα receptors agonists nuclear anticancer anti cancers anti-cancers acute promyelocytic leukemia APL antiproliferation differentiation ATRA-resistance AM-80 AMs 80 NSCs 608000 NSC-608000 NSC608000 selective α .alpha. alpha a RARalpha RAR.alpha. RARa RARβ β b beta .beta. RARb RARbeta RAR.beta. RARg RARgamma RAR.gamma. gamma .gamma. g RARγ γ binding binds antiproliferative effects cells inducing induces induction humans HL-60 HLs 60 differentiation suppress growth myeloid lymphoid malignant 0E-12
11959 AMD 3465 (hydrobromide) 185991-07-5 ≥95% 2013-02-04 7.384069981583 amd-3465-hydrobromide receptors antagonist infectious diseases immunlogy cancers HIV CXCR4 CXCL12 chemokind ligands antagoinst chemotaxis T-cells activation immunology AMD3465 AMD-3465 C-X-C chemokine receptors CXCR-4 CXCL-12 blocks binds inhibits inhibitions inhibitors calcium mobilization SupT1 HIC eosinophil granuloma formations Tcell T cells lymphoid tissues tumor growth cAMP xenograft models medulloblastoma glioblastoma 185991-24-6 7.384069981583
13965 AMI-1 (sodium salt) - ≥99% 2012-10-26 4.303867403315 ami-1-sodium-salt Arginine N-Methyltransferase Inhibitor-1 epigenetics inhibitors PRMTs histones modification methyltransferases proteins arginines methyltransferases lysines methyltransferases genes expression cells signaling signals transductions AMI1 AMI 1 permeable inhibits inhibitions yeast type 1 Hmt1p PRMT1 PRMT3 PRMT4, PRMT6, peptide-substrate binding HIV-1 HIV 1 HIV1 reverse transcriptase 20324-87-2 4.303867403315
14741 AMPK activator 849727-81-7 ≥95% 2013-07-26 20.415966850829 ampk-activator D942 diabetes cancers signals transductions cells permeable activates activators AMPs proteins kinases inhibits inhibitors mitochondrial complex I uptake up-take up-takes phosphorylation acetyl-CoA carboxylase myeloma prostates mTORC1 signaling survivin L6 myocytes blood glucose Zucker rats PC3 20.415966850829
13144 Anacardic Acid 16611-84-0 ≥98% 2010-02-12 9.014259166247 anacardic-acid 6-pentadecyl Salicylic Acid HAT histones acetylation P300 pCAF transcription NF-κB IκBα p65 6-pentadecyl salicyclic acids NSC 623096 cyclogallipharic 229596 333857 9.014259166247
11987 Anastrozole 120511-73-1 ≥98% 2012-08-27 29.954689889815 anastrozole ICI-D 1033; Anastrol; Arimidex™; ZD 1033 aromatase inhibitors androgens estrogen estrodial steroids biosynthesis Arimidex estrogen receptor-positive breasts cancers inhibits inhibitions peripheral tissues placental post-menopausal post menopausal postmenopausal ZD1033 ZD-1033 anastrazole anastrozole ICI-D1033 ICI-D-1033 ICID 1033 ICID-1033 29.954689889815
11679 Andrographolide 5508-58-7 ≥98% 2012-06-25 4.567204419889 andrographolide andrographis andrographolid 5953-53-7 101060-34-8 diterpenoids medicinal plants immunosuppression antithrombosis anti-inflammatory anti-inflammatory anti inflammatory antineoplastic anti-neoplastic neoplastic anti-viral antiviral viral anti-bacterial antibacterial bacterial anti-diabetic antidiabetic diabetics anti-oxidative stress antioxidative oxiddative antipyretic anti-pyretic pyretic anti-oedematogenic antioedematogenic oedematogenic anti-nociceptive antinociceptive nociceptive nuclear factor kappa B NF-κB p50 CYP1A endothelial cells E-selectin neutrophils allergic inflammations asthma CYP450 eselectin E selectin signaling signalling Andrographis paniculata inhibits inhibition inhibitors NFκB NF κB DNA 4.567204419889
11308 Anisomycin 22862-76-6 ≥98% 2012-02-13 15.658273480663 anisomycin Wuningmeisu C; Flagecidin; NSC 76712 2322-08-9 11023-48-6 antibiotics inhibitors proteins DNA stress-activated kinases MAP caspase-8 cancers immunology immunosuppressant pyrrolidines Streptomyces griseolus synthesis signal transduction pathways T cells skin mice anoikis epithelial apoptosis ECM distal tumors prostate metastasis NSC76712 NSC-76712 15.658273480663
600300 Annexin V FITC Assay Kit - 2010-05-11 56.893373793180 annexin-v-fitc-assay-kit assays kits measures measurements apoptosis cells death cycles tissues homeostasis dysregulation neurodegenerative diseases ischemic damages autoimmune disorders cancers drugs discovery signaling pathways membranes phospholipids phosphatidylserines phosphatidylethanolamines leaflets bilayers externalizations residues plasma phospholipids binding proteins fluorochrome-labeled fluorochromes fluorescence microscopy flow cytometry FC plate readers TUNEL TdT-mediated dUTP Nick-End Labeling analysis ISEL in situ end labeling DNA laddering detection fragmentation FITC-conjugated fluoresceins 56.893373793180
160780 Apaf-1 Polyclonal Antibody - 1.408425414364 apaf-1-polyclonal-antibody Apoptosis Protease-Activating Factor 1 apoptosis cell death caspases CED-4 Apaf2 Apaf3 Apaf-2 Apaf-3 Apafs antibodies Apaf1 CED4 western blots blotting WB protease-activating factors proteases antisera antiserum cancers immunoblotting 1.408425414364
14532 Apafant 105219-56-5 ≥98% 2013-05-24 6.324226519337 apafant WEB 2086 platelet-activating platelets activating inflammations cancers WEB 2086 factors PAFs receptors antagonists allergy angiogenesis allergies WEB2086 WEB-2086 activates activators water solubles selectives selects binds binding binders humans anti-inflammatory anti inflammatory antiinflammatory anticancer anti-cancer angiogenic anti-angiogenic 2086Bs phospholipids polymorphonuclear leukocytes monocytes macrophages vascular permeability cardiac output hearts hypotension uterine contractions inhibits inhibitors inhibitions 6.324226519337
10575 Apicidin 183506-66-3 ≥98% 2012-01-27 9.137217478654 apicidin OSI 2040 funfal toxins malaria HDAC HAT histones deacetylase transcriptions epigenetics anticancer anti-cancer antiproliferation antiparasitic anti-proliferation anti-parasitic apicomplexan parasites HDAC3 HDAC-3 NcoR HDAC3/NcoR class I HDACs p21 WAF1/Cip1 WAF1 Cip1 gelsolin cells cycle morphology inhibits inhibitors inhibitions chromatin cancers deacetylase modification 9.137217478654
14867 Aprepitant 170729-80-3 ≥98% 2013-10-24 3.339130434783 aprepitant Emend; L-754,030; MK 869; ONO-7436 221350-96-5 MK 0869 MK0869 ONO7436 MK-0869 emesis antiemetic antagonists NK1 receptors stress responses chemotherapy-induced nausea vomiting vomit CINV substances P neurokinins neurokinin-1 GPCRs 1 one substance-P antiemetic anti-emetic anti emetic antiemetic antagonizes humans NKs hNKs in vivo clinical use prevents chemotherapy-induced chemotherapy induced L754030 L-754030 L 754030 L-754,030 L754,030 754,030 754,030 MK869 MKs 869 MK-869 ONOs 7436 ONO-7436 ONO7436 reflex NK1 inositol phosphates signals transduction pathway cancers neuroscience 3.339130434783
10006797 Araguspongin B 123000-02-2 >90% 2005-09-09 42.536556169429 araguspongin-b membrane-permeable antagonists inositols inositol-1,4,5-trisphosphates receptors marine products Pacific basin sponges vasodilatory properties signal transductions messengers IP3 promotes mobilization calcium Ca2+ intracellular stores antagonizes calcium-releasing actions cerebral microsomes Xestospongin C neuroscience 42.536556169429
160737 ARC Polyclonal Antibody - 4.668922651934 arc-polyclonal-antibody Apoptosis Repressor with CARD apoptosis cell death domain DD CARD caspase antibodies western blots blotting WB antisera antiserum cancers immunoblotting IP immunoprecipitation 4.668922651934
14913 Arctigenin 7770-78-7 ≥95% 2013-09-06 94.482293650793 arctigenin 26687-78-5 41328-87-4 natural products an extracts from Arctium lappa A. antioxidants anti oxidants anti-oxidants inflammatory antiiflammatory anti-proliferative proliferative anti-viral viral anti-inflammatory antiproliferative antiviral pancreatic cancers influenza A virus neuroprotective Japanese encephalitis burdock plants medicines PANC-1 PANC1 PANCs 1 one glucose starvation kampo therapeutic cerebral artery occluded ischemic strokes 94.482293650793
15375 Arctiin New 20362-31-6 ≥98% 2014-01-16 94.025572853634 arctiin NSC 315527; Arctigenin-4-Glucoside natural products antioxidant anti-oxidant anti oxidant antiinflammatory inflammatory proliferative anti-proliferative viral anti-viral anti-inflammatory antiproliferative antiviral lignin glycoside arctigenin enterolactone cancers plants fruits burdock A. lappa influenza A intestinal bacteria metabolites MCF-7 MCF7 MCFs 7 seven infectious diseases arctii NSCs 315527 NSC315527 NSC-315527 aarctigenin glucosides 4 four 27193-46-0 94.025572853634
13321 ARP 100 704888-90-4 ≥98% 2009-10-07 9.598405239306 arp-100 CAY10609; MMP-2 Inhibitor III matrix metalloproteinases MMP-2 MMP2 MMP 2 ECM cancers cells migration inhibitors gelatinase A MMPs proteases HT1080 tumors invasive 9.598405239306
11815 Artemether 71963-77-4 ≥98% 2012-07-05 3.831933701657 artemether Paluther; Falcidol; SM 224; Larither; Malartem 159573-83-8 artemos artenam artesaph artesian dihydroartemisinin methyl ether gvither SM224 SM-224 β-artemether natural products malaria parasites schistosoma cancers inflammation antimalarial anti-malarial anti malarial artemisia plasmodium falciparum p. vivax p. falciparum lumefantrine trematodes schistosoma schistosomiasis 3.831933701657
11816 Artemisinin 63968-64-9 ≥98% 2012-08-01 0.983756626337 artemisinin NSC 369397 Arteannuin Artemef Artemisine Artemisinine 91487-93-3 plants artemisia malarials parasites genus Plasmodium combination therapy therapies trematodes Schistosomas Sesquiterpene lactones artemether artesunate cancers inflammatory inflammation kills natural products anti antimalarials anti-malarials Qinghosu Huanghuahaosu NSC-369397 NSC369397 QHS Qing Hau Sau Su Qinghaosu 0.983756626337
11817 Artesunate 88495-63-0 ≥98% 2012-07-09 1.131116022099 artesunate Zysunate; Saphnate; Armax 200; Arinate; Cosunate; Plasmotrin; WR 256283 83507-69-1 91487-94-4 112346-66-4 252637-87-9 1177476-35-5 1236362-31-4 armax200 armax-200 arsuamoon arsumax artesunata artesunate artesunic acid asumax dihydroqinghasu hemsuccinate gsunate forte plasmotrim qinghaozhi WR256283 WR-256283 malaria parasites schistosoma cancers inflammation anti-malarial antimalarial anti artemisinin plasmodium falciparum p. falciparum P. vivax trematodes artesunate artemether artemisinin inflammatory 1.131116022099
13250 (−)-AS 115 926657-43-4 ≥98% 2009-05-18 0.141804788213 -as-115 KIAA1363 MAGE monoacylglycerol LPA LPC lysophosphatidylcholine lysophosphatidic acid lipids signaling cancers signalling 0.141804788213
10009650 (+)-AS 115 - ≥98% 2009-05-19 0.141804788213 -as-115 KIAA1363 MAGE monoacylglycerol LPA LPC lysophosphatidylcholine lysophosphatidic acid lipids signaling cancer 0.141804788213
11226 AS-703026 1236699-92-5 ≥98% 2012-03-08 12.817928176795 as-703026 MSC1936369B AS 703026 AS703026 1204531-26-9 MEKs MEK1/2 MEK-1/2 MEK1 MEK2 ERKs Ras Raf inhibitors inhibits inhibitions cancers multiple myeloma EGFR signals transductions kinases cells biology 12.817928176795
700420 Ascorbate Assay Kit - 2010-09-01 150.074380445836 ascorbate-assay-kit Vitamin C Assay Kit; L-Ascorbic Acid Assay Kit kits assays measures measurements ascorbates six-carbon 6-carbon six 6 carbons lactones glucose livers mammalian species humans non-human primates guinea pigs gulonolactones oxidases acids 2-keto-1-gulonolactone diets dietary scurvy electrons donors enzymes collagen hydroxylations hydroxyls groups prolines lysines molecules carnitines fatty mitochondrias ATP adenosine triphosphates generations biosynthesis norepinephrines dopamines amides groups peptides hormones tyrosines metabolisms antioxidants chronics diseases cancers cardiovascular cataracts foods industry colors tastes odors plasmas serums urines fruits juices condensations reactions dehydroascorbic DHA o-phenylenediamines OPDA fluorescent fluorescences 4-hydroxy-2,2,6,6-tetramethylpiperidinyloxy TEMPOL condensed DFQ 3-(dihydroxyethyl)-furo[34-b]-quinoxaline-1-one OPD 150.074380445836
10946 ASH2L (human recombinant) - ≥90% 2011-06-29 6.233571428571 ash2l-human-recombinant Absent, small, or homeotic discs 2-like; Set1/Ash2 Histone Methyltransferase Complex Subunit Ash2 Isoform A epigenetics methyltransferases histones H3K4 genes regulations MLL proteins complex human homolog Drosophilia ash2 transcription 6.233571428571
11818 Asiatic Acid 464-92-6 ≥98% 2013-02-21 3.740677373763 asiatic-acid Dammarolic Acid; NSC 166063 inhibits inhibitors inhibitions inflammation cancers natural products wounds healing alzheimer’s diseases neurosciences inhibitors plants C. asiatica medicines traditional heals collagen cells cyckes arrest MCF 7 MCF-7 BACE1 ADAM10 SY5Y triterpene NSC166063 NSC-166063 3.740677373763
11496 AT-9283 New 896466-04-9 ≥98% 2014-01-02 89.103160210677 at-9283 1133385-​83-​7 inhibitors inhibits inhibitions kinases proteins cancers signals transductions intracellulars signaling ATs 9283 AT9283 AT-9283 auroras A B aurora-A aurora-B JAKs JAK-2 JAK-3 2 3 two three JAK2 JAK3 c-ABL c ABL cABL serine threonine tyrosines mitosis therapy therapies proliferation cells in vitro in vivo chemotherapeutics broad spectrums serine/threonine receptors non-receptors 89.103160210677
14490 ATAD2 bromodomain (human recombinant) - ≥90% 2013-05-22 0.669100470636 atad2-bromodomain-human-recombinant ANCCA; ATPase Family AAA Domain-containing Protein 2 genes regulations epigenetics chromatins researchers ATPase containing contains H3K14ac cancers proteins recombinant histones acetylations bromodomains AAA nuclear coregulator cancer-associated proteins lysines residues genes regulates regulating transcriptions acetylated small complexes readers marks markers targets promoters AAA+ ATPase-containing adenosines triphosphates enzyme-containing estrogens androgens receptors tumors E2F MYC signals signaling pathways binds bindings oncogenes transcriptional activity activities modifying 14 H3 cells cycles progressions 0.669100470636
13375 Atrazine 1912-24-9 ≥98% 2010-02-11 1.023756906077 atrazine herbicides plants cancers reproductive systems reproduction homones endocrines frogs genes expressions humans animals Gesamprim Atrazine 1.023756906077
15316 Auranofin New 34031-32-8 ≥98% 2014-02-17 0E-12 auranofin SKF 39162; NSC 321521; Ridauragold thiol Inhibitors inhibits inhibitions oxidative stress inflammation cancers arthritis infectious diseases gold-thiol gold thiol anti-inflammatory anti inflammatory antiinflammatory immunosuppressive complex bacteria viruses parasites aktil crisinor crisofin NSCs 321521 NSC321521 NSC-321521 ridaura ridauran SKF39162 SKFs 39162 SKF-39162 D 0E-12
14000 Auraptene 495-02-3 ≥98% 2012-11-27 0.407734806630 auraptene 7-Geranyloxycoumarin 5980-08-5 coumarin anti-inflammatory anti-carcinogenic anti-bacterial neuroprotective hepatoprotective leukocyte phase 2 enzymes Alzheimer's disease β-secretase β secretase .beta.-secretase beta-secretase b-secretase BACE1 BACE-1 inhibitors inhibits inhibitions antiinflammatory anticarcinogenic antibacterial chemopreventative citrus plants geranyloxyl moiety C-7 C7 C 7 aurapten 0.407734806630
600140 Autophagy/Cytotoxicity Dual Staining Kit - 2009-07-14 57.284581689029 autophagy-cytotoxicity-dual-staining-kit assays kits measuring measurement MDC cell-based autophagy cells cytotoxicity staining autofluorescent autofluorescence substances multilamellar body bodies ions trapping mechanisms membranes lipids probes autophagic vacuoles cultured degradation digestion intracellular lysosomes organelles misfolded proteins microorganisms cytoplasms double membranes autophagosomes autolysosomes homeostasis dysregulation cancers infections aging degenerative diseases stress death apoptosis 57.284581689029
10803 Autotaxin (human recombinant) - ≥95% 2011-04-04 15.703784530386 autotaxin-human-recombinant ENPP-2; Ectonucleotide Pyrophosphatase/Phosphodiesterase-2; Lysophospholipase D lipids hydrolysis lysophophatidyl choline lysophophatidic acids secreated glycosylated active 15.703784530386
700580 Autotaxin Inhibitor Screening Assay Kit - 2011-06-28 17.377434885556 autotaxin-inhibitor-screening-assay-kit ATX Inhibitor Screening Assay Kit kits assays measures measurements Ectonucleotides Pyrophosphatase-2 ENPP-2 Lysopholipases D hydrolysis lysophosphatidylcholines LPC lysophosphatidic acid LPA lipids mediators G protein-coupled receptors GPCRs neurogenesis angiogenesis smooth-muscles contraction platelets aggregations wounds healings ATX-LPA signaling tumors progression inflammation serums proteolytically peptides proteins N-glycosylation Asn53 Asn410 adipocytes cerebrospinal fluid multiple sclerosis livers fibrosis cancers genes chips analysis upregulated metastatic inhibits inhibition human 17.377434885556
13813 Axitinib 319460-85-0 98% 2010-08-09 18.340036065070 axitinib AG-013736 tyrosine kinases inhibitors inhibition inhibits VEGF VEGFR-1 VEGFR-2 VEGFR-3 c-kit PDGFR-β angiogenesis cancers tumors 790713-39-2 receptors RTKs 18.340036065070
14834 Azaserine 115-02-6 ≥98% 2013-08-22 6.573480662983 azaserine CN 15757; NSC 742; CI-337; O-Diazoacetyl-L-serine NSCs 742 NSC-742 NSC742 glutamines glutamine-dependent dependent amidotransferases inhibits inhibitions nucleotides biosynthesis anti-tumor anti-cancer antibiotic anti tumors cancers antitumors anticancers phosphoribosylformylglycinamidine synthetases N-formylglycineamidine ribotides synthetases FGAM glucosamine-6-phosphate isomerases GlcN-6-P hexosamines biosynthetics pathways UDP-N-acetylglucosamines UDP-GlcNAc O-linked glycoproteins antagonist active activity 438493-22-2 L-azaserine Ps 165 P-165 P165 CI-337 CIs 337 CI337 CNs 15757 CN-15757 CN15757 Streptomyces antioxidants hyperglycemic endothelial damages 6.573480662983
13111 AZD 4547 New 1035270-39-3 ≥98% 2013-12-17 61.223879680786 azd-4547 inhibitors inhibits inhibitions fibroblast growth factors receptors FGFRs tyrosines kinases FGFR1 FGFR2 FGFR3 antiproliferative antitumors 1 2 3 one two three anti-proliferative anti proliferative anti-tumors tumors AZDs 4547 AZD4547 AZD-4547 selective cells lines signal transduction biochemistry proteins cancers 61.223879680786
15406 AZD 5363 New 1143532-39-1 ≥98% 2014-03-04 0E-12 azd-5363 PKBα PKB.alpha. PKBalpha PKBa PKBβ PKB.beta. PKBbeta PKBb PKBγ PKB.gamma. PKBgamma PKBg PKBs Akts inhibitor Akt1 Akt2 Akt3 1 2 3 one two three P70S6K PKA ROCK2 MKK1 MSK1 MSK2 PKCγ PKC.gamma. PKCgamma PKCg PKCs PKGα PKG.alpha. PKGalpha PKGa PKGβ PKG.beta. PKGbeta PKGb PKGs PRKX RSK2 RSKS RSK3 cancers PIK3CA PTEN mutations antitumor tumors drugs resistances kinases pan-AKT pan inhibitors inhibitions inhibits pyrrolopyrimidine derived pyrrolopyrimidine-derived hematologic breast cancers intracellular signaling signals transduction AZD5363 AZD-5363 α .alpha. alpha a β .beta. beta b γ .gamma. gamma g 0E-12
11599 AZD 6244 New 606143-52-6 ≥98% 2013-10-29 20.861514362523 azd-6244 Selumetinib; ARRY-142886; NSC 741O78; Cl-1040 865610-​79-​3 inhibitors inhibits inhibitions cancers apoptosis proteins kinases signals transductions intracellular AZDs AZD-6244 6244 AZD6244 potent selective MEKs MEK1 MEK2 MEK-1 MEK-2 1 2 one two tumor growth suppressing suppression proto-oncogenes proto-oncogenes proto oncogenes Ras Raf MEK-1/2 MEK1/2 ½ NSCs 741O78 NSC-741O78 NSC741O78 ARRYs 142886 ARRY142886 ARRY-142886 Cl-1040 Cl4040 Cls 4040 Gs 00039805 G-00039805 G00039805 20.861514362523
11491 AZD 7762 860352-01-8 ≥98% 2012-04-11 13.230939226519 azd-7762 1019773-80-8 DNA damage repair checkpoints cells cycles kinases Chk1 Chk2 S phases G2 tumors cancers inhibitors inhibits inhibition AZD-7762 AZD7762 ATP Chk-1 Chk-2 Chk 1 Chk 2 13.230939226519
11324 b-AP15 New 1009817-63-3 ≥98% 2014-03-17 0E-12 b-ap15 330450-45-8 inhibitors cancers ubiquitin proteasomes deubiquitinases USPs UCHLs USP-14 USP14 14 UCHL-5 UCHL5 proteasome-associated DUBs b AP15 bAP15 ubiquitin-specific-processing protease 14 specific processing process carboxyl-terminal hydrolase isozyme L5 carboxyl terminal in vivo tumor cells T cells apoptosis TNF IV 0E-12
14166 BARD1 BRCT domains (human recombinant) New - ≥60% 2014-03-20 0E-12 bard1-brct-domains-human-recombinant BRCA1-Associated RING Domain Protein 1 DNA damages responses BRCT domains phosphoserines binding phosphothreonine binding Protein-protein interactions Double Strands breaks DSBs DNA Damages responses DDRs cancers BARD-1 EC 6.3.2 BRCA1 associated breast ovarian ovaries ovary tumors suppressors BRCA1 BRCA-1 repairs BRCA1/BARD1 heterodimers ubiquitin ligases p53 p53-dependent dependent apoptosis mRNA messengers RNA CstF-50 cleavage stimulating factor-50 factors DNA-damages DNA-repairs repairs one 0E-12
14742 Batimastat New 130370-60-4 ≥98% 2014-01-28 0E-12 batimastat BB-94 inhibitors cancers inhibits inhibitions proteases potent broad MMPs matrix metalloproteinases anti-proliferative anti proliferative antiproliferative anti-invasive antiinvasive invasive anti-metastatic metastatic antimetastatic BBs BB94 94 BB-9 MMP-1 MMP-2 MMP-3 MMP-7 MMP-9 MMP-13 MMP-14 1 2 3 7 9 13 14 TNFα-converting enzymes TNF.alpha.-converting TNFa-converting TNFalpha-converting TNF α .alpha. a alpha converting anti-proliferative TACE 0E-12
10009644 BAY-43-9006 284461-73-0 ≥98% 2011-09-13 37.018263574976 bay-43-9006 Nexovar®; Sorafenib inhibitors raf-1 b-raf receptors tyrosine kinases VEGF VEGFR PDGF PDGFR cancers angiogenesis apoptosis tumors cells cellular proliferation Flt-3 c-KIT carcinoma growth factor tosylate 37.018263574976
15005 Bazedoxifene acetate 198481-33-3 ≥98% 2013-04-17 5.443232044199 bazedoxifene-acetate TSE 424; Viviant 252555-09-2 selective estrogen receptors modulator SERM ERα ERβ 17β-estradiol breasts cancers antagonists osteoporosis cells cycles arrest ERs indole-based based indoles ER-α ER-β 17β estradiol ERalpha ER-alpha ER.alpha. ER-.alpha. ERa ER-a ER-beta ER-.beta. ER-b ERb ER.beta. ERbeta 17β estradiol 17b 17beta 17.beta. MCF-7 MCF7 MCF 7 T47D cycling downregulating downregulations cyclin D1 TSE-424 TSE 424 TSE424 viviant WAYTES WAY-TES WAY 5.443232044199
15576 Becatecarin New 119673-08-4 ≥98% 2014-02-27 0E-12 becatecarin BMY 27557; NSC 655649; XL 119; BMS 181176 134598-​30-​4 cancers DNA damage repairs inhibitors antibiotics 134598-30-4 analogs diethylaminoethyl antineoplastic rebeccamycin topoisomerases complexes inhibits inhibition cleavage apoptosis myelosuppressive in vivo transport substrates ATP binding cassette ABC transporters ABCG2 NSC655649 XL119 BMY27557 BMS181176 NSC-655649 XL-119 BMY-27557 BMS-181176 0E-12
11041 Betulin 473-98-3 ≥98% 2013-01-10 9.777891308130 betulin Trochol; NSC 4644 1406-58-2 1192133-66-6 betuline betulinic alcohol betulinol betulol NSC4644 NSC-4644 SREBP-2 cholesterol nuclear transcription factors natural products metabolic diseases anti-cancers atherosclerosis triterpene betulinic acids pentacyclic birch trees inhibits inhibitors inhibitions SREBPs SREBP2 SCAP-Insig binding binds ER lipids western-type atherosclerotic plaques LDLR Jurkat A549 carcinoma cells HeLa 9.777891308130
11686 Betulinic Acid New 472-15-1 ≥97% 2013-10-29 14.413541031317 betulinic-acid Lupatic acid; NSC 113090 natural products receptors agonists obese obesity vascular diseases atherosclerosis cancers anti-viral anti viral antiviral inflammations oxysterols plants triterpenoid bile acids G proteins coupled protein-coupled TGR5 TGR-5 TGRs 5 five genes livers HIVs HIV1 HIV-1 cancers betulic b-betulinic beta-betulinic .beta.-betulinic β-butulinic NSCs 113090 NSC113090 NSC-113090 inhibitors inhibits oxysterols vascular NF-κB NF-.kappa.B NF-kB signaling microRNA-33 miR-33 ATP-binding cassette ABC ABCA1 cytotoxic miR33 mi R33 RNA33 14.413541031317
11571 Bexarotene 153559-49-0 ≥98% 2012-04-06 1.617817679558 bexarotene LG 100069; Targretin; Ro 26-4455; SR 11247; LGD 1069 retinoid X receptors ligands agonist RXR genes expression cancers alzheimers diseases apoptosis angiogenesis metastasis cells proliferations β-amyloid amyloids βamyloid LG 100069 1069 69 LG-100069 LG-1069 LG-69 LGD 1069 LGD-1069 LGD1069 LG100069 LG1069 LG69 RO 26-4455 RO26-4455 RO-26-4455 RO 264455 RO-264455 RO264455 SR 11247 SR-11247 SR11247 targret targretin targretyn targrexin 1.617817679558
11022 BIBF 1120 656247-17-5 ≥95% 2011-11-10 34.890136400345 bibf-1120 Vargatef™ receptors tyrosine kinases inhibitors vascular endothelial growth factor VEGFR platelet-derived growth PDGFR fibroblasts FGFR angiogenesis cancers pulmonary fibrosis diseases 928326-83-4 34.890136400345
11492 BIBW 2992 New 439081-18-2 ≥95% 2013-11-05 21.564389921419 bibw-2992 Tomtovok™; Afatinib 915958-​11-​1 EGFR HER2 kinases erlotinib-resistance inhibitors anticancers erlotinib resistance inhibits inhibitions anti-cancers anti cancers BIBW2992 BIBW-2992 anilino-quinazoline aniline quinazoline in vtiro potent mutant forms isoforms tumors regression transgenic lungs selective dual EGFR/HER2 HER-2 HERs 2 two dual 21.564389921419
14250 Bicalutamide 90357-06-5 ≥98% 2013-03-26 59.610021786492 bicalutamide Casodex; ICI 176334; ZD 176334 151262-58-7 nuclear steroids hormones cosudex ICI176334 ICI-176334 ZD176334 ZD-176334 non-steroidal nonsteroidal steroidal antiandrogen anti-androgen anti antagonists prostate cancers SARM selective androgen receptors modulators binds binding proliferation therapy therapies non cells 59.610021786492
10011385 Bim/BOD (IN) Polyclonal Antibody - 2008-04-10 1.090435082873 bim-bod-in-polyclonal-antibody apotosis BH3 Bcl-2 Bcl-XL cancer immunoblotting WB IHC antibodies western blotting antiserum blots immunohistochemistry 1.090435082873
10960 Bisdemethoxycurcumin 24939-16-0 ≥98% 2011-08-09 6.669667448079 bisdemethoxycurcumin BDMC curcumin activators macrophages phagocytosis 1α,25-dihydroxyvitamin D, amyloid-β Alzheimer’s diseases cancers transcription genes expression p300 Wnt/β-catenin iNOS inflammation bisdemethoxy curcumin 33171-05-0 6.669667448079
13877 Bleomycin (sulfate) 9041-93-4 ≥95% 2012-10-15 42.149620421526 bleomycin-sulfate Blenoxane 134171-41-8 blexane antitumors antibiotics DNA breaks cells cycles superoxide free radicals cleavage Hodgkin's lymphoma cancers pulmonary fibrosis anti-tumors anti tumors anti-biotics biotics Streptomyces verticillus s. verticillus chelating metalions pseudoenzyme glycopeptide Hodgkins 42.149620421526
12030 Bosutinib 380843-75-4 ≥98% 2013-04-15 33.303010219741 bosutinib SKI 606 inhibitors cancers signals transduction potent dual inhibits inhibitions c-Src Abl cSrc regulating regulates tumors growth differentiation nanomolar SRC TEC Yes Fgr Lck Fyn kinases SKI606 SKI 606 SKIs SKI-606 33.303010219741
14433 bpV(HOpic) (potassium salt) 722494-26-0 ≥90% 2013-04-11 162.227504412216 bpv-hopic-potassium-salt Bisperoxovanadium(HOpic) Inhibitors proteins tyrosines phosphatases signal transductions bisperoxovanadium PTPs PTEN PI3-kinase bpVs bpV-HOpic bpV-(HOpic) bpVHOpic inhibits inhibitions vascular endothelial PTP-1βB PTP-β PTP1βB PTP1β .beta. beta b 169291-75-2 162.227504412216
15438 bpV(HOpic) (potassium salt, technical grade) Exclusive New 722494-26-0 ≥80% 2014-01-15 131.410834868017 bpv-hopic-potassium-salt-technical-grade Bisperoxovanadium(HOpic) 169291-75-2 inhibitors inhibitions inhibits proteins tyrosines phosphatases PTENs PTPs signal transduction bisperoxovanadium PI3-kinase cancers bpV HOpic potassium salts technical grades vascular endothelial in vitro cells viability upregulations 131.410834868017
13331 bpV(phen) (potassium hydrate) 171202-16-7 ≥99% 2013-02-06 60.418538853079 bpv-phen-potassium-hydrate Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V); Bisperoxovanadium(phen) diabetes inhibitis inhibitions inhibits phosphatases signals transductions insulin receptors cells signaling SHIP-2 SHIP2 SHIPs bisperoxovanadium bpV phens proteins tyrosines PTPs PTEN vascular endothelial SH2 domains containing inositol 5’-phosphatase signals PI3-kinase 42494-73-5 60.418538853079
14434 bpV(pic) (potassium hydrate) 148556-27-8 ≥96% 2013-04-11 74.915695019951 bpv-pic-potassium-hydrate Bisperoxovanadium(pic) Inhibitors proteins tyrosines phosphatases signal transductions bisperoxovanadium PTPs PTEN PI3-kinase insulin IRK bpVpic bpV-pic bpV-(pic) PTP-1βB PTP-β PTP1βB PTP1β .beta. beta b receptors 68782-50-3 inhibits inhibitions 74.915695019951
14167 BRCA1 BRCT domains (human recombinant) - ≥90% 2013-08-29 22.407407407407 brca1-brct-domains-human-recombinant Breast Cancer Type 1 Susceptibility Protein DNA damages responses BRCT domains phosphoserines binding phosphothreonines protein-protein interactions binds binders breasts ovarian 22.407407407407
11071 BRD2 bromodomain 1 (human recombinant; GST-tagged) - ≥95% 2011-10-21 6.214691819120 brd2-bromodomain-1-human-recombinant-gst-tagged RING3; Bromodomain containing protein 2; RNF3 BET proteins BRD2 BRD3 BRD4 I-BET genes expression histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomain epigenetics lysine inflammatory inflammation mitosis viral host 6.214691819120
11070 BRD2 bromodomain 2 (human recombinant; GST-tagged) - ≥95% 2011-10-21 6.331950155330 brd2-bromodomain-2-human-recombinant-gst-tagged Bromodomain containing protein 2; RING3; RNF3 BET proteins BRD2 BRD3 BRD4 I-BET genes expression histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomain epigenetics lysine inflammatory inflammation mitosis viral host 6.331950155330
11069 BRD2 bromodomains 1 and 2 (human recombinant) - ≥90% 2011-12-20 6.453718427548 brd2-bromodomains-1-and-2-human-recombinant RING3; RNF3; Bromodomain containing protein 2 BET proteins BRD2 BRD3 BRD4 I-BET genes expressions histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomains epigenetics lysines regulations trandcription proteins domains nucleosomes BRDT BRD-T cells inflammatory inflammation mitosis viruses viral hosts binding binds molecules inhibitors inhibits inhibition humans diseases 6.453718427548
11285 BRD3 bromodomain 1 (human recombinant) - ≥95% 2012-07-05 2.348202837587 brd3-bromodomain-1-human-recombinant ORFX; RING3L; Bromodomain containing protein 3; RING3-like protein BRD3 genes expressions histones chromatin acetylation bromodomains epigenetics BRDs BETs BRD2 BRD 2 BRD-2 BRD 3 BRD-3 BRD4 BRD 4 BRD-4 2.348202837587
14658 BRD3 bromodomain 2 (human recombinant) - ≥95% 2013-06-06 1.565851601021 brd3-bromodomain-2-human-recombinant Bromodomain containing protein 3; RING3L; ORFX; RING3-like protein recombinant proteins genes regulations epigenetics chromatins research cancers BRD3 expressions histones acetylation bromodomains BRDs BRD2 BRD 2 BRD-2 BRD 3 BRD-3 BRD4 BRD 4 BRD-4 BRDT BRD-T RING3-like 1.565851601021
600640 BRD3 bromodomain 2 TR-FRET Assay Kit New - 2013-12-03 73.588728618518 brd3-bromodomain-2-tr-fret-assay-kit ORFX; Bromodomain containing protein 3; RING3-like protein; RING3L kits assays measures measurements acetylations histones lysines residues roles epigenetics regulations genes transcriptions factors acetylated small molecules proteins domains bromodomains recruits recruiting regulatory complexes nucleosomes chromatins structures expressions BET family class tandem Extra Terminal BRD2 BRD4 BRDT 2 3 4 T BRDs BRD-2 BRD-3 BRD-4 BRD-T cells cellular processes inflammation inflammatory mitosis viral hosts viral/host interactions isolated binds binding tails couple marks transcriptional targets promoters inhibitors inhibits inhibitions bromodomain/histones I-BET JQ-1 IBET I JQ1 JQ 1 therapeutics human diseases disrupts disrupting formations activations activated macrophages protects protections bacteria bacteria-induced induced inductions sepsis lipopolysaccharide-triggered lipopolysaccharides triggered LPS-triggered LPS endotoxic shocks enantiomerically (+)-JQ1 (-)-JQ1 stereoisomers peptides bromodomain-peptides displacement chemical probes oncogenesis cancers tumorigenesis growths tumors TR-FRET time-resolved fluorescence resonance energy transfers characterizations bromodomain/acetylated interactions fluorophores europium Eu3+ chelates biotinylated ligands allophycocyanin APC-labeled avidins biotins 73.588728618518
14864 BRD3 bromodomains 1 and 2 (human recombinant) - ≥95% 2013-08-09 1.482946593001 brd3-bromodomains-1-and-2-human-recombinant ORFX; Bromodomain containing protein 3; RING3L; RING3-like protein BRD3 genes expressions histone chromatin acetylation epigenetics bromodomains extra terminals BETs BRD-3 BRD 3 three BRD2 BRD-2 2 two BRD-4 BRD4 4 four BRDT cellular processed inflammatory expressions mitosis viral host interactions promoters histones lysine regulation transcription domains nucleosomes tandem humans diseases 1.482946593001
11068 BRD4 bromodomain 1 (human recombinant; GST-tagged) - ≥60% 2011-10-21 6.402895010633 brd4-bromodomain-1-human-recombinant-gst-tagged HUNK1; Bromodomain containing protein 4; MCAP BET proteins BRD2 BRD3 BRD4 I-BET genes expression histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomains epigenetics lysine nucleosomes cellular inflammatory mitosis viral hosts 6.402895010633
11720 BRD4 bromodomain 1 (human recombinant; His-tagged) - ≥95% 2012-07-05 2.997352173131 brd4-bromodomain-1-human-recombinant-his-tagged Bromodomain containing protein 4; MCAP; HUNK1 BET proteins BRD2 BRD3 BRD4 I-BET genes expression histones chromatin acetylation IBET BRD BRD-2 BRD 2 BRD-3 BRD 3 BRD-4 BRD 4 bromodomains epigenetics extra terminal 2.997352173131
11066 BRD4 bromodomain 2 (human recombinant; GST-tagged) - ≥95% 2011-10-21 6.425711627718 brd4-bromodomain-2-human-recombinant-gst-tagged HUNK1; Bromodomain containing protein 4; MCAP BET proteins BRD2 BRD3 BRD4 I-BET genes expression histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomains epigenetics lysine nucleosomes cellular inflammatory mitosis viral hosts 6.425711627718
11721 BRD4 bromodomain 2 (human recombinant; His-tagged) - ≥95% 2012-07-05 2.169966373499 brd4-bromodomain-2-human-recombinant-his-tagged MCAP; Bromodomain containing protein 4; HUNK1 BETs proteins BRD2 BRD3 BRD4 I-BET genes expression histones chromatin acetylation IBET BRDs BRD-2 BRD 2 BRD-3 BRD 3 BRD-4 BRD 4 bromodomains epigenetics 2.169966373499
14822 BRD4 bromodomains 1 and 2 (human recombinant; aa 2-477) - ≥70% 2013-08-09 0.410534445822 brd4-bromodomains-1-and-2-human-recombinant-aa-2-477 MCAP; Bromodomain containing protein 4; HUNK1 BET proteins BRD2 BRD3 BRD4 I-BET genes expressions histones chromatin acetylation IBET BRDs BRD-2 BRD-3 BRD-4 bromodomains epigenetics extra terminals BRDs 2 3 4 two three four transcription 0.410534445822
11052 BRD4 bromodomains 1 and 2 (human recombinant; aa 49-460) - ≥90% 2011-12-20 6.375789200382 brd4-bromodomains-1-and-2-human-recombinant-aa-49-460 Bromodomain containing protein 4; MCAP; HUNK1 BET proteins BRD2 BRD3 BRD4 I-BET genes expressions histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomains epigenetics lysines regulations trandcription proteins domains nucleosomes BRDT BRD-T cells inflammatory inflammation mitosis viruses viral hosts binding binds molecules inhibitors inhibits inhibition humans diseases 6.375789200382
600830 BRD4 bromodomains 1 and 2 TR-FRET Assay Kit - 2013-08-30 33.262763433181 brd4-bromodomains-1-and-2-tr-fret-assay-kit HUNK1; Bromodomain containing protein 4; MCAP kits assays measures measurements acetylations histones lysines residues roles epigenetics regulations genes transcriptions factors acetylated small molecules proteins domains bromodomains recruits recruiting regulatory complexes nucleosomes chromatin structures expressions BET family class tandem Extra Terminal BRD2 BRD3 BRDT 2 3 4 T BRDs BRD-2 BRD-3 BRD-T cells cellular processes inflammation inflammatory mitosis viral hosts viral/host interactions isolated binds binding tails couple marks transcriptional targets promoters inhibitors inhibits inhibitions bromodomain/histones I-BET JQ-1 IBET I JQ1 JQ 1 therapeutics human diseases disrupts disrupting formations activations activated macrophages protects protections bacteria bacteria-induced induced inductions sepsis lipopolysaccharide-triggered lipopolysaccharides triggered endotoxic shocks enantiomerically (+)-JQ1 (-)-JQ1 stereoisomers peptides bromodomain-peptides displacement chemical probes oncogenesis cancers tumorigenesis growths tumors TR-FRET time-resolved fluorescence resonance energy transfer characterization bromodomain/acetylated interactions fluorophores europium Eu3+ chelates biotinylated ligands allophycocyanin APC-labeled avidins biotins 33.262763433181
14491 BRD7 bromodomain (human recombinant) - ≥40% 2013-06-14 0.186002367797 brd7-bromodomain-human-recombinant Bromodomain containing protein 7; Protein CELTIX-1 genes regulations epigenetics chromatin reseach cancers recombinants proteins histones acetylation bromodomain lysine residues domains transcriptions nucleosomes regulating regulates targets promoters subunits polybromo-associated BRG1 PBAF components SW1/SNF remodeling complexes tumors supressors cofactors p53 breasts tumorigenicity BRCA1 dependents estrogen receptors α expressions nasopharyngeal carcinomas colorectal transcriptional silencing PRMT5 PRC2 regions complex 2 switch sucrose breasts cancers type 1 proteins arginine methyltransferases 5 polycomb repressive non-fermentable 0.186002367797
11509 BRD9 bromodomain (human recombinant) - ≥95% 2012-04-20 1.125773107749 brd9-bromodomain-human-recombinant Bromodomain containing protein 9 BRD9 genes expressions histones chromatin acetylation bromodomains epigenetics BET domains transcription Extra Terminal domain BRDs BRDT inflammatory mitosis viral/host interactions Rhabdomyosarcoma antigen MU-RMS-40.8 1.125773107749
11649 BRDT bromodomain 2 (human recombinant) - ≥95% 2012-06-25 1.956835697989 brdt-bromodomain-2-human-recombinant CT9; Bromodomain testis-specific protein; RING3-like protein; Cancer/testis antigen 9; BRD6 gene expression histones chromatin acetylation bromodomain epigenetics RING3 transcriptional cofactors testis specific spermatogenesis lung cancer BRD-T BRD T BRDs 1.956835697989
11284 BRG1 bromodomain (human recombinant) - ≥95% 2012-03-05 2.983951819532 brg1-bromodomain-human-recombinant Protein BRG-1; ATP-dependent helicase SMARCA4; BAF190A Mitotic growth and transcription activator; BRG1-associated factor 190A BRG1 genes expressions histones chromatin acetylation bromodomains epigenetics SWI/SNF SWI SNF cancers tumors suppressors Protein brahma homolog 1 2.983951819532
11289 BRM bromodomain (human recombinant) - ≥95% 2012-03-01 1.000687206888 brm-bromodomain-human-recombinant SMARCA2A/B; SWI/SNF ATPase BRD1 genes expressions histones chromatin acetylation bromodomains epigenetics SWI/SNF SWI SNF ATP dependent chromatin SWI/SNF-related, matrix associated, actin-dependent regulator of chromatin 1.000687206888
11650 BRPF3 bromodomain 1 (human recombinant) - ≥95% 2012-06-25 1.246453415200 brpf3-bromodomain-1-human-recombinant Bromodomain and PHD Finger Containing 3; MGC:58603; KIAA1286 BRPF3 genes expression histones chromatin acetylation bromodomains epigenetics MOZ transcriptional cofactors MORF HAT MOZ/MORF 1.246453415200
14843 Busulfan 55-98-1 ≥98% 2013-08-29 5.968404815561 busulfan Mielosan; Myeloleukon; Mylecytan; Myleran; Milecitan; Busulphan; NCI C01592; NSC 750 alkyl sulfonate alkylsulfonate alkyl-sulfonate antineoplatic agents intrastrand interstrand intra strands inter crosslinks DNAs profound prolonged reduction hematopoietic progenitors alkylating ANs 33501 AN-33501 AN33501busilfex busulphan CBs 2041 CB2041 CB-2041 citosulfan GTs 2041 GT2041 GT-2041 41 GT41 GT-41 glyzophrol mablin mielevcin NCIs C01592 NCIC01592 NCI-C01592 NSCs NSC750 NSC-750 NSC750 sulfabutin sulphabutin tetramethylenes X149 X 149 X-149 Busilvex Leucosulfan Mielucin Mileran Mitostan Misulban 5.968404815561
15371 Butein New 487-52-5 ≥95% 2014-01-23 8.044714548803 butein 2’,3,4,4’-tetrahydroxy Chalcone natural products oxidative injury injuries antioxidants anti-oxidants anti oxidants inflammation cancers inhibitors inhibits inhibitions histones deacetylases plants polyphenols phenols chalcones potent oxidant tones immune responses 5-lipoxygenase 5-LO 5-LOX P. falciparum angiotensins Src activators activates TSA tetrahydroxy enoyl-acyl-carrier proteins reductases kinases sirtuins activators trichostatins A 8.044714548803
14484 Buthionine Sulfoximine 83730-53-4 ≥98% 2013-05-21 13.607348066299 buthionine-sulfoximine L-Buthionine-S,R-Sulfoximine; BSO; NSC 326231 oxidative injury injuries inhibitors inhibits inhibitions cancers apoptosis cells deaths glutathiones stress γ-glutamylcysteine g-glutamylcysteine gamma-glutamylcysteine .gamma.-glutamylcysteine synthetases GSH drugs drug-resistance resistances BSO irreversibles synthases tissues damages toxicity chemotherapeutics agents tumors L-glutathiones rates limiting rate-limiting enzymes induces inductions synthesis toxic limits limiters 13.607348066299
10549 C646 328968-36-1 ≥98% (mixture of isomers) 2013-02-18 20.188204419889 c646 cancers acetyltransferases chromatin research inhibitors inhibits inhibitions histones modifications genes regulations epigenetics histones modifications acetylation regulations acetyltransferases C-646 C 646 inhibitors inhibits inhibitions p300 p-300 blocks melanoma leukemia lungs prostates cells in vitro memory 20.188204419889
10005270 (±)-C75 191282-48-1 ≥98% 2004-09-22 80.409863609890 -c75 inhibits inhibitors inhibition fatty acids synthases FAS cerulenin cytotoxicity apoptosis cancers anorexigenic stable weight loss feeding endocrinology 80.409863609890
13999 Cafestol 469-83-0 ≥98% 2012-11-28 0.135359116022 cafestol natural products diterpenes cholesterol triglycerides receptors activation angiogenesis unfiltered coffee serum humans dietary ApoE3Leiden inhibits inhibitions inhibitors umbilical veins endothelial migration tubes formations forms Matrigel 0.135359116022
15279 CAL-101 New 870281-82-6 ≥98% 2014-01-21 146.666666666666 cal-101 GS-1101; Idelalisib GS-1101 phosphatidylinositol-3-kinase PI3K signaling cells growths cancers p110δ inhibitors B cells Akt apoptosis chemotaxis CLL leukemia GS1101 GSs 1101 CALs 101 CAL101 phosphatidylinositol 3 three kinases cell-permeable permeable inhibits inhibitions poly ADP ribose polymerases tumors Bcells B-cells signals selective transductions kinases chemokines poly(ADP-ribose) 146.666666666666
15383 Calphostin C New 121263-19-2 ≥95% 2014-01-09 89.021055477160 calphostin-c PKF 115-584; Cladochrome E; UCN 1028C UCN-1028C UCNs 1028C UCN1028C inhibitors inhibits inhibitions proteins kinases C PKC D1 PLD1 phospholipases D2 PLD2 antitumors anti tumors anti-tumors apoptosis metabolites fungus C. cladosporioides polycylic hydrocarbons cancers intracellular signaling signals kinases transduction PKFs 115-584 115 584 115584 PKF115-584 PKF-115-584 UCNs 1028C UCN1028C UCN-1028C 125411-36-1 selective activation lights exposures 89.021055477160
12076 Canertinib (hydrochloride) 289499-45-2 ≥98% 2012-11-06 6.230800411889 canertinib-hydrochloride PD 183805; CI 1033 267243-28-7 338796-35-3 HCl dihydrochloride hydrochloride CI1033 CI-1033 PD183805 PD-183805 receptors tyrosine kinases EGFR HER-2 HER-3 HER-4 proliferation tumors inhibitors, anti-cancers inhibits inhibitions anticancer pan-ErbB ErbB quinazoline HERs HER2 HER3 HER4 proliferation malignant peripheral nerves sheath cells neuroblastoma acute myeloid leukemia T98G HCT8 breasts resistance proteins BCRP 6.230800411889
13285 Cannabidiol dimethyl ether 1242-67-7 ≥98% 2009-05-19 12.510690607735 cannabidiol-dimethyl-ether CBDD; Cannabidiol-2',6'-dimethyl ether 15-lipoxygenases 15-LOs dioxygenase fatty acids inflammation thrombosis cancer LDL oxidation inhibitions inhibition inhibiting cannabinoids cbs synthetic 12.510690607735
14589 Cantharidin 56-25-7 ≥98% 2013-06-04 15.019347118001 cantharidin NSC 61805 1351357-43-1 kantaridin NSC61805 NSC-61805 serine/threonine proteins phosphatases okadaic acids 1 PP1 2A PP2A inhibitors cells cycles anti-cancer anticancers anti cancers 2B PP-1 PP PP-2A PP2B PP-2B simulates progressions induces premature mitosis topically topical anti-wart warts antiwarts treatments active activates cervical tongues neuroblastoma bones leukemia ovarian colons cancers toxins produced produces blisters beetles inhibits inhibitions serines threonines 15.019347118001
10487 Capecitabine 154361-50-9 ≥98% 2010-08-16 2.519558011050 capecitabine Ro 09-1978; Xeloda® Capecitibine Capecytabine Captabin 5-Fluorouracil 5-FU cancers prodrugs thymidine phosphorylase fluoropyrimidine carbamate inhibits inhibition inhibitors thymidylate synthase liver enzymes 158798-73-2 958887-39-3 Deoxyribonucleoside Cytosine Cytosine Deoxyribonucleoside Deoxyriboside Cytosine Cytosine Deoxyriboside Deoxycytidine CDR 2.519558011050
13112 Carboplatin New 41575-94-4 ≥95% 2013-12-04 50.182817318456 carboplatin NSC 201345; NSC 241240; Paraplatin®; Ribocarbo-L platinum antineoplastic DNA repairs damages apotosis anti cancers anticancers anti-cancer cytotoxic agents ovarian lungs crosslinks crosslinking chemotherapy antineoplastic anti-neoplastic neoplastic adducts tumors solids inhibits inhibitions inhibitors CBDCA carbomedac carboplatinium carbosin cycloplatin JMs 8 JM8 JM-8 eight NSCs 201345 241240 NSC-201345 NSC-241240 NSC201345 NSC241240 paraplatin ribocarbo L 70903-55-8 110681-25-9 936543-00-9 replication transcription 50.182817318456
89800 Carnosol 5957-80-2 >96% 78.727647987371 carnosol antioxidants tumors herbs carcinogenesis rosemary Rosmarinus officinalis extracts polyphenolic inhibits inhibitors inhibition 78.727647987371
360745 Caspase-3 (human) Blocking Peptide - 1.400015785319 caspase-3-human-blocking-peptide Apopain; CPP32; ICE3; Yama control peptides blots blotting western cpp-32 ice-3 apoptosis effectors caspases cell death wb antibodies 1.400015785319
160790 Caspase-9 Polyclonal Antibody - 8.519977250568 caspase-9-polyclonal-antibody Apaf-3; ICE-LAP6; MCH6 apoptosis cell death Apaf-1 apafs caspase-3 caspases antibodies Apaf1 western blots blotting WB an tisera antiserum cancers immunoblotting 8.519977250568
11695 Catharanthine 2468-21-5 ≥98% 2013-04-01 1.491712707182 catharanthine (+)-3,4-Didehydrocoronaridine 47416-77-3 catharanthin anticancers cancers anti anti-cancers alkaloids synthesis vinblastine vincristine antimitotic Vinca vindoline plants antibiotics catharanthus roseus c. chemotherapy 1.491712707182
600740 Cathepsin S Cell-Based Assay Kit - 2012-10-24 33.442400245549 cathepsin-s-cell-based-assay-kit kits assays CBAs measuring measurement enzymes activity activities lysosomes lysosomal cysteines proteases MHC II 2 antigens processing presentations expressed expressions spleen lymph nodes monocytes macrophages antigen-presenting cells immune systems immune-related system-relateds diseases levels tumors metastasis obesity diabetes diabetic progression cancers inflammatory proteins factors pathogenesis pharmaceuticals cell-based assays S-specific substrates Ac-KQKLR-AMC fluorescent high throughput screening HTS therapeutics activity RAW264.7 cells lysates supernatants positive controls inhibits inhibitors inhibitions Z-Phe-Leu-COCHO 33.442400245549
13704 Cav3.2 Calcium Channel Monoclonal Antibody (Clone S55-10) - 2009-11-12 0.607734806630 cav3-2-calcium-channel-monoclonal-antibody-clone-s55-10 antibodies CACNA1H genes epilepsy up-regulations up regulations upregulations prostate cancers androgen-independent androgen independent western blotting blots WB fusion protein immunohistochemistry IHC immunocytochemistry ICC 0.607734806630
89740 CAY10398 193551-00-7 ≥98% 13.167671058223 cay10398 PX 089274; MD 85 reversible inhibitors histone deacetylase HD1 inhibits inhibitions CAY-10398 hdacs HDAC-1 HDACs HDAC 1 HDAC1 HDACIS 519054-34-3 13.167671058223
70635 CAY10416 443919-96-8 ≥95% 2007-07-24 10.177636586863 cay10416 COX-2 cyclooxygenases 5-LO lipoxygenases inflammation inhibitors prostates cancers PC3 LNCaP carcinomas apoptosis inhibition inhibits chemotherapy cells lines 10.177636586863
10005019 CAY10433 537034-17-6 ≥95% 2005-01-05 15.391460460963 cay10433 N-phenyl-N'-(2-Aminophenyl)hexamethylenediamide; BML-210 HDAC deacetylases histone inhibits inhibitors inhibition cancer cells differentiation gene expression regulation Trichostatin A nuclear extracts deacetylation transcription factors FOXO3 SIRT1 H2O2 hydrogen peroxides BML210 15.391460460963
10005033 CAY10444 Exclusive 298186-80-8 ≥98% 2004-10-05 49.381710953258 cay10444 BML-241 receptors antagonists S1P3 EDG3 sphingosines sphingosine-1 sphingosine1 phosphates Hela cells G-proteins CAY-10444 BML241 49.381710953258
10006546 CAY10465 Exclusive 688348-33-6 >98% 2005-09-09 9.742596685082 cay10465 resveratrol analogs analogues aryl hydrocarbons receptors agonists AhRs ligand-dependents ligands xenobiotics PDM 11 PDM11 PDM-11 estrogen dioxin poisonings stilbene xenobiotics polyaromatics soot coal tar 9.742596685082
10008872 CAY10503 890854-82-7 ≥98% 2007-08-02 44.471270718232 cay10503 apoptosis antiproliferation cancers differentiation HL60 cells cycles proliferative positive markers CD14 CD11b CD11c monocytic granulocytic 44.471270718232
10009078 CAY10505 328960-84-5 ≥98% 2009-11-04 7.954950276243 cay10505 phosphoinositide 3-kinase immunity autoimmune inflammation PI3Kγ PI3Kα PI3Kβ PI3Kδ casein kinases 2 CK2 phosphorylation PKB/Akt macrophages neutrophil recruitment cancer PI3s T2Ds PI3Ks PI3K.gamma. PI3Kg 7.954950276243
10009536 CAY10512 Exclusive 139141-12-1 ≥97% 2007-07-18 8.622062615101 cay10512 analogs resveratrol nuclear factors NFkB NF-.kappa.B immunity inflammation stress growth apoptosis trans-stilbene activation cancers NF-kB inhibition inhibtors inhibits atherosclerosis 8.622062615101
10010301 CAY10554 267654-00-2 ≥95% 2007-12-01 8.520189423836 cay10554 BML-259 cell cycle Cdk5 Cdk2 inhibitors inhibits inhibition cancers BML 259 BML259 CDKs neurodegenerative diseases 8.520189423836
10010043 CAY10561 Exclusive 933786-58-4 ≥98% 2008-03-06 5.307624309392 cay10561 Pyrazolylpyrrole ERK Inhibitor MEK Ras Raf ERK2 proliferation cell cycles cancers apoptosis inhibition inhibit inhibitors 5.307624309392
18218 CAY10572 845714-00-3 ≥98% 2009-03-02 9.634069981583 cay10572 PHA 767491 inhibits inhibition inhibitors cdc7 kinases pyrrolopyridinone DNA synthesis cells death cycles apoptosis p53 cancers Cdk9 antitumor agents anti-tumor 9.634069981583
10011247 CAY10574 140651-18-9 >95% 2008-09-04 13.594111547425 cay10574 Cdk2 cyclin E Cdk9 inhibitors inhibits inhibition anticancer cell cycle CAN508 CDKs 13.594111547425
10011256 CAY10577 300675-28-9 ≥95% 2008-09-02 0.533646408840 cay10577 inhibitors inhibits inhibition CK2 kinase cell signaling apoptosis cancers 0.533646408840
10011264 CAY10578 19231-60-8 ≥95% 2008-08-26 0.520791896869 cay10578 inhibitors inhibits inhibition kinase cell signaling CK2 apoptosis cancers isoindolineacetic acids 0.520791896869
16835 CAY10580 Exclusive 64054-40-6 ≥96% 2009-03-16 65.729037446285 cay10580 PGEs PGE2 receptors inhibitors inhibits inhibition antagonist blockers EP4 cAMPs bones fromation resorption cancers atherosclerosis 65.729037446285
16838 CAY10581 Exclusive 1018340-07-2 ≥97% 2009-05-08 2.658563535911 cay10581 indoleamine 2,3-dioxygenase IDO cancers inhibitors tumors inhibition inhibited naphthoquinones 2.658563535911
10012682 CAY10585 934593-90-5 ≥97% 2008-11-06 36.558638284042 cay10585 Hypoxia Inducible Factor-1α Inhibitor HIF-1α HIF1α hypoxia cancers transcriptions factors VEGFs erythropoietin inhibitors inhibits inhibition 36.558638284042
10009797 CAY10591 Exclusive 839699-72-8 ≥98% 2008-04-21 30.362389502762 cay10591 SIRT1 Activator 3; Sirtuin 1 Activator 3 p53 HDACs inhibits inhibitors inhibitions SIRTs sirtuins class III TNFalpha TNF.alpha. THP-1 cells anti-obesity anti-diabetic 30.362389502762
13281 CAY10598 346673-06-1 ≥98% 2010-05-07 66.837283609576 cay10598 Prostaglandins E2 PGE2 receptors EP4 bone formation cancers atherosclerosis agonists EP1 EP2 EP3 DP FP IP TP neuroprotection renal dysfunction inflammation neuro-protection TCS 2510 66.837283609576
10009796 CAY10602 374922-43-7 ≥95% 2009-07-15 15.554597912829 cay10602 SIRT1 Activator 1 SIRTs sirtuins inflammation deacetylase NF-kB NFkB NF-κB NFκB 15.554597912829
13146 CAY10603 1045792-66-2 ≥95% 2009-06-18 18.970612645795 cay10603 HDAC 6 inhibitors inhibits inhibition tubulin microtubule pancreatic cancers SAHA HDAC6 HDAC-6 HDACs HDACIs potent selective cells 18.970612645795
13291 CAY10616 Exclusive 586410-08-4 ≥98% 2009-12-01 10.888674033149 cay10616 resveratrols apoptosis cancers leukemia HL-60 cells HL60 HL 60 multidrug-resistance multidrug resistance multi-drug multi-drug-resistant daunorubicin etoposides citarabines phenols cytarabines HL60R 10.888674033149
13670 CAY10618 Exclusive 1202580-59-3 ≥95% 2011-03-18 7.870736648250 cay10618 NMPRTase Inhibitor nicotinamides phosphoribosyltransferases NAMPTs NAD+ cancers inhibitors autophagy inhibited inhibition inhibits 7.870736648250
13371 CAY10621 120005-55-2 ≥98% 2010-02-16 3.940779005525 cay10621 SPHK 1 Inhibitor 5C; SKI 5C sphingosines kinases Sphk sphingosine-1-phosphates S1P SphK1 SphK2 cancers inhibitors inhibits U937 cells proteins kinase C PKC SKI5C SKI-5C 3.940779005525
13836 CAY10625 137346-42-0 ≥95% 2010-06-23 3.822674033149 cay10625 apoptosis Smac Diablo Survivin cancers antagonists INCENP doxorubicin caspase-3 caspase-7 Aurora B kinases Borealin caspases cell-permeable antagonists smac/diable smac-diablo 3.822674033149
13838 CAY10626 Exclusive 1202884-94-3 ≥98% 2010-08-23 11.813208669783 cay10626 PI3Kα mTOR cancers signal transduction inhibitors inhibits inhibition phosphatidylinositol 3-kinase PtdIns PIs 11.813208669783
10791 CAY10647 Exclusive 1253697-49-2 ≥98% 2012-04-16 2.923756906077 cay10647 cancers inhibitors inhibits inhibition tumors tubulin polymerization cells CAY-10647 CAY 10647 growth 2.923756906077
10743 CAY10650 Exclusive 1233706-88-1 ≥98% 2011-06-14 0.828729281768 cay10650 cPLA2α cPLA2 inhibitors inflammation anti-inflammatory dermatitis metabolite phospholipase cytosolic prostaglandins PGs leukotrienes synthesis 10662 CAY-10650 CAY10641 CAY-10641 0.828729281768
11140 CAY10657 494772-86-0 ≥98% 2012-03-05 2.681049723757 cay10657 NF-κB, transcription factors inflammation arthritis chemotherapy IKK IKK2 inhibitors IKB thiophenecarboximide inhibits inhibitions IKK-2 IKK 2 NFkB NF kB Rel NF-kB/Rel pro-inflammatory genes cytokines chemokines interferons MHC proteins growth factors cells adhesion cancers 2.681049723757
9001252 CAY10668 Exclusive - ≥98% 2013-01-18 0E-12 cay10668 inhibitors cancers estrogen prostates breast hormones inhibits inhibitions CAY-10668 CAYs 10668 stilbene trans-stilbenoid CYPs CYP1B1 CYP450 4-[(E)-2-(2,6-Dimethoxy-phenyl)-vinyl]-3-methoxy-phenol 0E-12
14744 CAY10677 1443253-20-0 ≥98% 2013-08-20 0.760233918129 cay10677 Icmt Inhibitor 15 post-translational post translations posttranslations proteins prenylation cancers Isoprenylcysteine carboxyl methyltransferase analogs Icmt inhibitors cysmethynil antiproliferative inhibits inhibitions CAY-10677 CAYs 10677 anti-proliferative anti proliferative breasts MDA-MB-231 cells prostate PC3 signals transductions intracellular signaling c-terminus growth oncogenesis methylation prenylcysteine 0.760233918129
15403 CAY10683 New 1477949-42-0 ≥95% 2014-03-14 8.521988950276 cay10683 Santacruzamate A natural products inhibitors inhibits inhibitions histones deacetylases cancers epigenetics HDACs potent cyanobacterium symploca HDAC2 HDAC6 HDAC-2 HDAC-6 2 6 two six HCT116 HCTs 116 HCT-116 colon HuT78 HuT-78 HuTs 78 T cells dermal fibroblasts santacruzamate-A 8.521988950276
10004985 Caylin-1 Exclusive 1207480-88-3 ≥98% 2005-09-09 18.835153906866 caylin-1 caylin1 mdm-2 cancer Nutlin-3 analogs p53 inhibits inhibitors inhibition interaction Mdm2 negative regulators activity chlorine substituents phenyl rings growth HCT-116 cells promotes 18.835153906866
10005002 Caylin-2 Exclusive 1392830-09-9 ≥98% 2004-07-12 15.602306629834 caylin-2 apoptosis cancer p53 inhibits inhibitors induces apoptotic re-activation reactivation antioncogenic tumors xenografts HCT-116 caylin2 15.602306629834
13172 CBHA 174664-65-4 ≥98% 2009-06-24 12.622004838768 cbha m-Carboxycinnamic Acid bis-Hydroxamide; Histone Deacetylase Inhibitor II histones deacetylase HDACs HDAC1 HDAC3 apoptosis cancers neuroblastoma tumors retinoic acids inhibitors inhibits inhibition 12.622004838768
14768 CBX1 (human recombinant) - ≥95% 2013-08-06 8.563921974776 cbx1-human-recombinant Chromobox Protein Homolog 1; Heterochromatin Protein 1 Homolog β; HP1-β; HP1Hs-β; p25β; M31; Modifier 1 Protein; Heterochromatin Protein p25 epigenetics heterochomatin chromodomain histones H3K9 chromoshadow domains proteins HP1 HP-1 N-terminal CSD CBXs di-methylated tri-methylated lysine 9 H3 H3K9me2 H3K9me3 BRCA2 EMSY breasts ovarian cancers DNA chromatin DDR DNA damages responses 8.563921974776
14769 CBX2 chromodomain (human recombinant) - ≥90% 2013-10-03 7.179661098862 cbx2-chromodomain-human-recombinant Chromobox Protein Homolog 2 (Drosophila Pc Class); MGC10561; M33; SRXY5; CDCA6; Cell Division Cycle Associated 6; Modifier 3 chromobox chromodomains polycomb prc1 epigenetics transcriptional regulation Xist X inactivation 3 histones CBX-2 CBXs 2 two polycombs repressive complex 1 PRC1 PRC-1 PRCs 1 one H3Ks T cells T-cells chromosomes proteins 7.179661098862
11235 CBX5 (human recombinant) - ≥95% 2012-05-03 4.343922774880 cbx5-human-recombinant Antigen p25; Heterochromatin Protein 1-α; Chromobox Protein Homolog 5; HP1-α epigenetics heterochomatin chromodomains histones H3K9 Chromoshadow domains HP-1 HP1α HP1 α HP1s HP1β HP1ɣ hinges domain SETDB1 methylation homodimerization DNA damage response DDR CBX1 CBX3 chromatin-associated proteins chromatin associated genes regulations formations CBX lysines 9 H3 H3K9me2 H3K9me3 methylated silencing CSD DDR 4.343922774880
10787 CCG-100602 1207113-88-9 ≥98% 2011-11-22 8.467265193370 ccg-100602 Rho signaling signal transduction cancers inhibitors SRF serum response factors transcription CCG-1423 megakaryoblastic leukemia 1 MKL1 prostate analogs PC-3 CCG100602 CCG 100602 CCG1423 CCG 1423 cells DNA binding RHOA/C-mediated MKL-1 8.467265193370
10010350 CCG-1423 285986-88-1 ≥98% 2007-09-20 18.500102604577 ccg-1423 Rho signaling transduction cancers proliferations anti-proliferation anti-tumor serum response factor GTPase inhibits inhibitors inhibition signalling 18.500102604577
15075 CCG-203971 New 1443437-74-8 ≥90% 2014-03-11 0E-12 ccg-203971 cancers inhibitors genes regulations inhibits inhibitions CCG203971 CCGs 203971 SRE serum responses elements prostates cells lines PC-3 PC3 PC 3 three migrations Rho MLK1 MLK-1 MLKs 1 ones SRF megakaryoblastic leukemia factors transcriptional pathways RhoA RhoC transcription metastasis signals transduction intracellular signaling 0E-12
10012591 CCT018159 171009-07-7 ≥98% 2008-12-09 0.827900552485 cct018159 inhibitors inhibits inhibition cancers Hsp90s Hsp72 kinases tumor cells 17-AAG 17AAG CCT 018159 CCT-018159 0.827900552485
10004804 CD150 Monoclonal Antibody (Clone IPO-3) - 2005-03-21 0.242817679558 cd150-monoclonal-antibody-clone-ipo-3 CDw150; IPO-3; SLAM type transmembrane glycoproteins signals signalling transduction neoplastic cells antibodies antisera antiserum antioncogenic immunohistochemistry IHC flow cytometry immunoprecipitation IP immunocytochemistry ICC receptors ligation Hodgkins lymphoma leukemia tumors cancer ipo3 cd-150 b-cells t-cells tonsils cancers FC 0.242817679558
10004837 CD27 Monoclonal Antibody (Clone 203.6) - 2005-09-16 1.685976896032 cd27-monoclonal-antibody-clone-203-6 antibodies antisera antiserum IHC immunohistochemistry ICC immunocytochemistry FACS flow cytometry type II transmembranes glycoproteins leukocytes proteins tetraspanin superfamily antigens alternative splicing isoforms human B cells pro-B plasma T macrophages neutrophils platelets erythrocytes Anti-CD37 immunophenotyping neoplasia hairy chronic lymphocytic non-Hodgkin's lymphoma expression lymphocytes T cells NK activated memory monocytes granulocytes dendritic B anti-CD45 mAB lymphoid malignancies malignant cancer FC 1.685976896032
10004835 CD34 Monoclonal Antibody (Clone ICO-115) - 2005-09-16 1.426595835104 cd34-monoclonal-antibody-clone-ico-115 antibodies antisera antiserum ICC immunocytochemistry FACS flow cytometry type I transmembranes glycoproteins proteins antigens isoforms stem cells embryonic fibroblasts neurons Anti-CD34 differential staining acute leukemias cancers malignant malignancies ICO115 FC 1.426595835104
10208 CD34 Monoclonal FITC Antibody (Clone ICO-115) - 2008-07-23 29.391712707182 cd34-monoclonal-fitc-antibody-clone-ico-115 antibodies antiserum antisera flow cytometry immunofluorescence FC IF transmembranes glycoproteins leukemias stem cell lines 29.391712707182
10004718 CD37 Monoclonal Antibody (Clone IPO-24) - 2005-09-16 1.685976896032 cd37-monoclonal-antibody-clone-ipo-24 antibodies antisera antiserum IHC immunohistochemistry ICC immunocytochemistry FACS flow cytometry type III transmembranes glycoproteins leukocytes proteins tetraspanin superfamily antigens alternative splicing isoforms human B cells pro-B plasma T macrophages neutrophils platelets erythrocytes Anti-CD37 immunophenotyping neoplasia hairy chronic lymphocytic non-Hodgkin's lymphoma expression lymphocytes T cells NK activated memory monocytes granulocytes dendritic B anti-CD45 mAB lymphoid malignancies malignant cancer FC 1.685976896032
71610 CD437 New 125316-60-1 ≥95% 2013-12-12 53.333333333333 cd437 AHPN atypical retinoid RRM retinoid-related retinoid related molecules agonist retinoic acids receptors RARγ antitumors anti tumors anti-tumor cancers anti-cancers anticancers apoptosis cells cycles arrest DNA damage CDs CD-437 437 RARs RARgamma RARg RAR.gamma. cytotoxic melanoma breasts non-small lungs prostate 53.333333333333
10004597 CD45 Monoclonal Antibody (Clone BRA-55) - 2005-08-23 1.685976896032 cd45-monoclonal-antibody-clone-bra-55 antibodies antisera antiserum WB western blots blotting IHC immunohistochemistry ICC immunocytochemistry FACS flow cytometry type transmembranes glycoproteins leukocytes antigens alternative splicing isoforms CD45RA CD45RB CD45RC CD45RO expression lymphocytes cells NK activated memory monocytes granulocytes dendritic anti-CD45 mAB lymphoid malignancies malignant cancer BRA55 immunoblotting FC 1.685976896032
10004604 CD95 Monoclonal Antibody (Clone IPO-4) - 2004-06-17 0.620081031307 cd95-monoclonal-antibody-clone-ipo-4 APO-1; Fas; Tumor Necrosis Factor Receptor Superfamily, Member 6; TNFRSF6; Apoptosis Antigen; APT glycoproteins blots blotting antibodies antisera antiserum DNA binding anti-oncogenic apoptosis cancers p53 re-activator reactivator induces apoptotic re-activation reactivation antioncogenic immunocytochemistry immunohistochemistry IHC icc FC flow cytometry 0.620081031307
81035 CDDO 218600-44-3 ≥95% 2012-10-26 17.320583744346 cddo Bardoxolone; RTA 401 Nrf2 antioxidant ARE Keap1 oxidative stress inflammations cancers apoptosis inducers inhibitors inhibits inhibitions iNOS COX-2 COX2 ROS RNS heme oxygenase-1 oxygenase eotaxins eotaxin-1 PPARgamma PPAR.gamma. PPARg PPAR-gamma PPAR-.gamma. PPAR-g PPARγ PPAR-γ oleanane triterpenoid cellular nitric oxide INFγ INF-γ INF-gamma INF-.gamma. INF-g INFg INF.gamma. INFgamma ROS/RNS peroxisome proliferator activated receptor RTA401 RTA-401 17.320583744346
11883 CDDO methyl ester 218600-53-4 ≥98% 2012-10-26 21.179036783020 cddo-methyl-ester RTA 402; NSC 713200; TP-155; Bardoxolone methyl iNOS COX-2 COX2 apoptosis inflammations cancers signalings antidiabetic activity oxidative stress NF-κB NFκB NF-kappaB NFkappaB NF.kappa.B NFkB NF-.kappa.B NF-kappaB NF-kB C28 C-28 CDDOs nitric oxide Nrf2 antioxidant ARE Keap1 oxidative stress inflammations cancers apoptosis inducers inhibitors inhibits inhibitions iNOS COX-2 COX2 ROS RNS heme oxygenase-1 oxygenase eotaxins eotaxin-1 PPARgamma PPAR.gamma. PPARg PPAR-gamma PPAR-.gamma. PPAR-g PPARγ PPAR-γ oleanane triterpenoid cellular nitric oxide INFγ INF-γ INF-gamma INF-.gamma. INF-g INFg INF.gamma. INFgamma ROS/RNS peroxisome proliferator activated receptor RTA402 RTA-402 NSC713200 NSC-713200 TP155 TP 155 21.179036783020
15154 Cdk2 Inhibitor II New 222035-13-4 ≥95% 2013-12-12 53.333333333333 cdk2-inhibitor-ii Cyclin-Dependent Kinase 2 Inhibitor II; SC-221409 inhibitors cells cycling cancers cycles Cdks Cdk2 Cdk-2 2 two II inhibits inhibitions selective potent cyclin-dependent cyclin dependent A E S phase G2-M benzylidne indolin analogs permeable reversible ATPs compound 3 SC-221409 SCs 221409 SC221409 53.333333333333
11495 Cediranib 288383-20-0 ≥98% 2013-10-22 11.352242002591 cediranib AZD 2171; Recentin™; ZD 2171 557795-​03-​6 790713-​41-​6 inhibitors inhibits inhibitions cancers angiogenesis vasculogenesis receptors tyrosine kinases growth factors VEGF VEGFR EGF EGFR PDGF PDGFR FGF FGFR biochemistry signals transductions potent VEGFR-1 VEGFR-2 VEGFR-3 VEGFR1 VEGFR2 VEGFR3 1 one 2 two 3 three non-receptors nonreceptors non AZD2171 AZD 2171 AZD-2171 ZD2171 ZD-2171 ZDs platelet-derived fibroblast endothelial tubules formations xenografts tumors proteins kinases signals transduction 11.352242002591
10008672 Celecoxib 169590-42-5 ≥98% 2013-08-08 12.967107270120 celecoxib Onsenal; Xilebao; SC-58635; Celebrex™; Celebra; YM-177 anti-inflammatory diaryl heterocycle inhibitors inhibits inhibitions COXs COX2 2 two cyclooxygenases cyclooxygenase-2 COX-2 antitumors anti-tumors anti tumors antiinflammatory inflammatory cancers apoptosis selective therapeutics gastrointestinal NSAIDs cardiovascular chemopreventive proapoptotic sulfonamides nonsteroidal drugs YM 177 YMs 177 YM177 SC58635 SC 58635 SCs 58635 eurocox medicoxib apopeotsis non-steroidal 12.967107270120
10009349 Cell Cycle Phase Determination Kit - 2007-04-20 43.804986187845 cell-cycle-phase-determination-kit assays kits measures measurements microscopy flow cytometry plate readers regulators cells transcription factors DNA proteins division proliferation induction inhibition fixation permeabilization staining sub-G1 G0 G2 S propidium iodide apoptosis cancer cell-based assay cell based assay cba 43.804986187845
11092 Ceranib-2 1402830-75-4 ≥98% 2011-12-19 3.214972375690 ceranib-2 ceramides ceramidase sphingosines sphingosine-1-phosphate S1P cells proliferation cancers paclitaxel tumors inhibitors lipids inhibits inhibition endogenous ovarian SKOV3 growth toxicity fatty acids N-acyl malignant apoptosis S1P non-lipid increases increased 3.214972375690
15500 Cercosporamide New 131436-22-1 ≥95% 2014-01-28 0E-12 cercosporamide natural products inhibitors inhibits inhibitions infectious diseases cancers kinases protein diabetes phytotoxin cercosporidium fungus potent Pkc1 Pkc Pkc-1 1 one mammalian Mnk isoforms leaves cassava plants PKC-like candida oral orally (-) - 0E-12
10005647 Cerulenin 17397-89-6 ≥98% 2004-09-01 87.625301821157 cerulenin tumor cells fatty acid synthases FAS inhibits inhibitors inhibition cytotoxicity apoptosis cancer diet obesity D02.065.327 87.625301821157
10009853 CFSE Cell Division Assay Kit - 2010-01-15 67.406646496536 cfse-cell-division-assay-kit derivative carboxyfluorescein diacetate, succinimidyl ester CFDA-SE cells proliferation growth factors receptors surfaces signaling molecules transcription factors DNA deoxyribonucleases proteins divisions cascades human pathological diseases cancers cell-tracing fluorescent fluorescence dyes proliferative activity parent generations daughter acetate groups molecules cleaved background unstained staining CFSE-labeled radioactivity radioactive labeling divisions inductions inhibitors inhibits inhibitions in vitro models flow cytometry fluorochromes fluorescein 67.406646496536
13156 Chaetocin 28097-03-2 ≥95% 2010-10-18 42.946075046040 chaetocin histones methyltransferases HMTs genes expressions epigenetics inhibitors oxidative stress cancers theoredoxin reductase-1 TrxR1 inhibits inhibition chetocin chaetocin A (+)-chaetocin piperazines regulations 42.946075046040
10011286 Chenodeoxycholic Acid 474-25-9 ≥95% 2009-02-25 22.956238836412 chenodeoxycholic-acid CDCA; Fluibil; Hekbilin; Anthropodeoxycholic Acid; Kebilis; Ulmenide FXR biles acids cholesterol oxidative stress glutathione cancers atherosclerosis diabetes hyperlipidemia CDA 22.956238836412
14437 Chetomin 1403-36-7 ≥98% 2013-04-11 13.266077348066 chetomin NSC 289491 hypoxia cancers inhibitors inhibits inhibitions chaetomium species antibacteriasl antifungals anti-bacterials anti bacterials bacteria anti-fungals fungal fungus hypoxia-inducible factors HIFs signals signaling cells growths grow tumors xenografts 1390-81-4 35808-58-3 NSC289491 NSC-289491 natural products smal molecules binds bindings HIF-1α HIF-1a HIF-1alpha HIF-1.alpha. HIF-2α HIF-2a HIF-2alpha HIF-2.alpha. p300 attenuates attenuations pathways in vivo mice mouse HIF-dependent 13.266077348066
13686 Chidamide 743420-02-2 ≥98% 2010-08-10 26.054541436464 chidamide HDACs histones deacetylase H3 acetylation colons cancers cells inhibitors inhibits inhibiton LoVo HT-29 HT29 HT 29 cycle arrest chidamides oncogenic signalling signaling kinases Benzamides 26.054541436464
70930 Chlorogenic Acid 327-97-9 ≥95% 31.341484806629 chlorogenic-acid 3-O-Caffeoylquinic acid; Heriguard; NSC 407296 antioxidants acids plants metabolism polyphenolic 31.341484806629
13501 Chromosome Associated Protein-C Polyclonal Antibody (aa 281-297) - 2009-09-22 0E-12 chromosome-associated-protein-c-polyclonal-antibody-aa-281-297 CAP-C antibodies SMC WB western blots immunoblotting blotting hCAP-C hCAPC hCAP C hSMC1 hCAP-E hCAP E hCAPE hSMC3 chromosomes structured maintenance 0E-12
13503 Chromosome Associated Protein-C Polyclonal Antibody (aa 47-61) - 2009-09-22 0E-12 chromosome-associated-protein-c-polyclonal-antibody-aa-47-61 CAP-C antibodies SMC WB western blots immunoblotting blotting hCAP-C hCAPC hCAP C hSMC1 hCAP-E hCAP E hCAPE hSMC3 structural maintenance chromosomes 0E-12
14188 Chrysomycin A 82196-88-1 ≥98% 2013-02-13 8.556160220994 chrysomycin-a Albacarcin V; NSC 613946; Virenomycin V inhibitors inhibits inhibitions natural infectious diseases cancers antibiotics chrysomycin-a chrysomycin-V V A anti-tumors antitumor streptomyces DNA bacterias tumors transplants transplantable NSC-613946 NSC613946 8.556160220994
14189 Chrysomycin B 83852-56-6 2013-02-13 8.354469631614 chrysomycin-b Albacarcin M; Virenomycin M antibiotics natural products inhibitors cancers inhibitions inhibits infectious disease chrysomycin-B Streptomyces analogs antitumor anti-tumor transplant transplantable tumors DNA damage lungs topoisomerase II cross-linking cross linking histones 3 M chrusomycin-M GRP78 UVs lights 8.354469631614
11021 CHS-828 200484-11-3 ≥98% 2012-03-14 1.132596685083 chs-828 GMX 1778 pyridyl cyanoguanidine anti-tumor tumors inhibitors inhibits inhibition NAMPT NF-κB cancers CHS828 CHS 828 humans breasts lungs mice MCF-7 NYH GMX-1778 GMX1778 1.132596685083
11580 CI-1040 212631-79-3 ≥98% 2013-06-17 13.798895027624 ci-1040 PD 184352 PD184352 PD-184352 CI1040 CI 1040 MEKs inhibitors PD 0325901MAPKs ERKs cancers CI1040 CI 1040 benzhydroxamate inhibits inhibitions in vitro mitogen-activated mitogens activated proteins MAPs adenosine triphosphates tumors extracellular signal-regulated kinases signals regulated potent signaling intracellular transductions threonine methyl ethyl ketones RAS RAF pathways humans ATP phosphorylation mouse mice colons PD184352 PD-184352 13.798895027624
12084 CI-994 112522-64-2 ≥98% 2012-10-09 20.533130755064 ci-994 PD 123654; Goe 5549; Tacedinaline; N-Acetyldinaline 919788-39-9 Goe5549 Goe-5549 PD123654 PD-123654 inhibitors HDACs class I HDACs HDAC1 HDAC2 HDAC3 HDAC8 anticancer antitumor Cl994 Cl 994 HDAC-1 HDAC-2 HDAC-3 HDAC-8 anti-cancer anti-tumor anti cancers tumors in vitro recombinant in vivo therapy genes regulations 20.533130755064
15194 CID-1067700 New 314042-01-8 ≥95% 2013-11-19 55.555555555556 cid-1067700 ML-282 Molecular Libraries Initiatives SIDs 85747738 CIDs 1067700 Ras GTPases GTP GDP nucleotide inhibitors inhibitions inhibits SID85747738 SID-85747738 CID-1067700 CID1067700 Rab7 Rab-7 Rabs 7 MLs 282 ML-282 ML282 competitive Ras-related cancers intracellular signaling signals transduction family Arf Rho Rab subfamilies regulates cellular processes membrane trafficking control cells proliferation cell physiology switching active inactives conformational states binding binds alterations genetic diseases pockets preventing prevents BODIPY-linked BODIPY linked 55.555555555556
10012583 cis-ACCP 777075-44-2 ≥95% 2009-02-10 0E-12 cis-accp MMP2 MMPs MMP 2 MMP9 MMP-9 9 tumors cancers extracellular matrix type IV collagen cell migration artritis osteoprosis 0E-12
13199 cis-trismethoxy Resveratrol 94608-23-8 ≥98% 2009-03-25 9.742480662983 cis-trismethoxy-resveratrol cis-Trimethoxy Stilbene resveratrol anti-mitotic growth inhibitors colon cancers tubulin polymerization polyamines putrescine spermidine cis-Trimethoxy resveratrol 3,5,4'-trimethoxystilbene 3,5,4'-trimethoxy-cis-stilbene trismethoxy inhibitor inhibition caco-2 caco 2 cells AHR antagonists aryl hydrocarbon receptors 9.742480662983
12085 Cladribine 4291-63-8 ≥98% 2012-10-04 28.558178288786 cladribine Jk 6251; Biodribin; NSC 105014; RWJ 26251; Leustatin 24757-90-2 cladarabine CldAdo Jk6251 Jk-6251 leustat NSC105014 NSC-105014 NSC 105014-F NSC105014-F NSC-105014-F NSC-105014F NSC105014F NSC 105014-F cancers leukemia hairy cells inhibitors lymphocytes cytotoxic cytotoxicity 2-chlorodexoyadenosine analogs proliferating proliferation non-dividing nondividing non dividing inhibits inhibition inhibitors hematologic malignancies multiple sclerosis adenosine 2CdA 2-CdA CdA 28.558178288786
10599 Cl-Amidine 913723-61-2 ≥95% 2011-08-29 37.543011049723 cl-amidine inhibitors PAD4 PAD-4 cancers epigenetics amidines proteins arginine deiminase 4 arthritis PADs cytotoxic HL-60 HL60 HT-29 mice joints auto antibodies HL 60 MCF7 MCF-7 MCF 7 HT29 citrulline IgG HT 29 cells lines ClA mouse serum autoantibodies auto-antibodies PAD3 PAD-3 3 PAD1 PAD-1 1 37.543011049723
14125 Clofarabine 123318-82-1 ≥98% 2013-04-11 4.042799263351 clofarabine Clolar; Evoltra nucleotides inhibitors inhibits cancers inhibitions apoptosis Clofarex CAFdA nucleosides analogs leukemias mitochondrial transmembranes potentionals ribonucleotides reductases DNA deoxyribonucleic acids polymerases polymerase-a polymerase-α polymerase-.alpha. polymerase-alpha alpha .alpha. a α cytoxins cytotoxic K562 K-562 K 562 myelogenous growths solid tumors induces inductions primary chronic lymphocytic lymphocytes 4.042799263351
14813 Clomifene 911-45-5 ≥95% 2013-08-15 2.321546961326 clomifene Clomiphene B receptors antagonists steroids endocrinology reproductive biology SERM selective estrogen modulators ERs gondadotropin-releasing gonadotropic relseases hormones ovulations cancers ERα ER.alpha. ERβ ER.beta. follicles lutein 2.321546961326
580110 Clusterin (human) EIA Kit - 2011-08-02 15.757044198895 clusterin-human-eia-kit Apolipoprotein J; Apo-J; pADHC-9; TRPM-2; AAG4; SGP-2; CLI; KUB-1; Clusterin (human) ELISA Kit apolipoproteins Up-regulated in Azheimer's diseases brains Ku70-binding proteins 1 sulfated glycoproteins 2 aging-associated genes 4 complement lysis inhibitors testosterone-repressed prostate messages secreted disulfide-linked heterodimeric amyloid lipids bacteria leptin immunoglobulins endocytic receptors LDLs low-density lipoprotein-related LPR2 LPR8 8 endocytosis tissues mammals mammalian cells plasma serums semen cultures media medium developmental remodeling apoptotic neurodegeneration injury stress inhibits inhibition apoptosis carcinogenesis genes CLU ELISAs EIAs enzymes immunoassays kits measures measurements human supernatants 15.757044198895
9000760 Colchicine 64-86-8 ≥98% 2011-05-25 19.519206875383 colchicine microtubules polymerization mitosis anti-proliferation anti-inflammatory gout uric acids antiinflammatory antiproliferation 19.519206875383
10007412 Combrestatin A4 117048-59-6 ≥98% 2007-07-26 14.834048934491 combrestatin-a4 CA4; Combretastatin A4; CRC 87-09 inhibitors inhibition inhibits tubulin polymerization tumors CSA4 CSA-4 IMR32 neuroblastomas Hs746T carcinomas CFPAC-1 CFPAC1 MCF-7 MCF7 cancers inhibitory CA4 cells growth pancreatic breast gastric CA-4 combretastin 14.834048934491
14951 Concanavalin A 11028-71-0 2013-09-25 2.407438016529 concanavalin-a 12612-33-8 lectin jack beans C. ensiformis canavalia glycoproteins agglutination mitogenesis apoptosis glycolipids affinity chromatography purifications autoimmune hepatitis AIH immune response T cells T-cells cross-links cross links cell-surface surface concanacalin-A Con A ConA Con-A plants immunology biology carbohydrates 2.407438016529
14426 Cordycepin 73-03-0 ≥98% 2013-05-23 2.430405156537 cordycepin NSC 401022; 3'-Deoxyadenosine; NSC 63984 153-49-1 48171-89-7 nucleosides analogs 3’-deoxyadenosine polyadenylation inhibitors inhibits inhibitions DNA deoxyribonucleic acids ribonucleic synthesis RNA synthesis anti-proliferative pro-apoptotic anti-inflammatory antiproliferative anti proliferative proapoptotic pro apoptotic inflammatory antiinflammatory sinensis 3’-dATP NSCs NSC-401022 NSC-63984 NSC401022 NSC63984 anti-inflammatories cordyceps triphosphates ATP-dependent biological poly A tails mRNA length activates AMPK kinases mTOR signals signaling 2.430405156537
14743 Costunolide 553-21-9 ≥98% 2013-08-19 0.386075949367 costunolide Costus lactone; Melampolide; NSC 106404 11028-78-7 25333-06-6 46814-17-9 62458-56-4 80750-19-2 126621-28-1 cancers inhibitors apoptosis sesquiterpenes lactones plants extracts medicines oils cells Akt endometriotic epithelial STAT3 STAT-3 STATs 3 three THP-1 THP1 THP 1 one telomerase NALM-6 NALMs NALM6 six 6 NSC106404 NSC-106404 NSCs 106404 costus 0.386075949367
360107 COX-2 (human) Blocking Peptide - 24.533646408839 cox-2-human-blocking-peptide PGHS-2; Cyclooxygenase 2; Prostaglandin H Synthase 2 peptides prostaglandins PGHS-2 COX2 PGHS2 western blots blotting synthases controls immunohistochemistry IHC cyclooxygenases WB antibodies 24.533646408839
160112 COX-2 Monoclonal Antibody (Clone CX229) - 70.655738489871 cox-2-monoclonal-antibody-clone-cx229 Cyclooxygenase 2; Prostaglandin H Synthase 2; PGHS-2 prostaglandins inflammation cancers arthritis western blots blotting immunohistochemistry IHC WB immunocytochemistry ICC antibodies cox2 pghs2 pghs-2 synthases cyclooxygenases antisera antiserum cyclooxygenase immunoblotting 70.655738489871
160126 COX-2 (mouse) Polyclonal Antibody (aa 584-598) - 67.682633517495 cox-2-mouse-polyclonal-antibody-aa-584-598 Cyclooxygenase 2; Prostaglandin H Synthase 2; PGHS-2 immunohistochemistry IHC Western blotting WB antibodies blots cox2 PGHS2 PGHS-2 synthases prostaglandins mouse cyclooxygenases antisera antiserum cancers immunoblotting 67.682633517495
10010096 COX-2 (mouse) Polyclonal FITC Antibody Exclusive - 2008-04-23 22.471012891344 cox-2-mouse-polyclonal-fitc-antibody Cyclooxygenase 2; PGHS2; Prostaglandin H Synthase 2 antibodies prostaglandins thromboxanes prostacyclins arachidonic acids FC flow cytometry ICC immmunocytochemistry WB western blots blotting immunoblotting IF immunofluorescence 22.471012891344
700200 COX Fluorescent Activity Assay Kit - 2008-07-24 49.872950926226 cox-fluorescent-activity-assay-kit Cyclooxygenase Fluorescent Activity Assay Kit cyclooxygenases synthases enzymes cox-1 cox1 cox-2 cox2 prostaglandins PGs synthase-1 synthase-2 pghs-1 pghs1 pghs-2 pghs2 assays kits peroxidase activity cellular homeostasis antiinflammatory NSAIDs nonsteroidal anti-inflammatory drugs fluorescence human recombinant ovine isozyme-specific inhibits inhibitors inhibition ADHP 10-acetyl-3,7-dihydroxyphenoxazine resorufin 49.872950926226
11288 CREB-binding protein bromodomain (human recombinant) - ≥95% 2012-04-24 1.446849092442 creb-binding-protein-bromodomain-human-recombinant cAMP-Response Element-binding Protein 1 CREB-1; CBP; CREBBP CREBBP genes expressions histones chromatin acetylation bromodomains epigenetics CREB p53 cAMP response element-binding protein 1.446849092442
12087 Crizotinib 877399-52-5 ≥98% 2013-02-28 24.219656230816 crizotinib Xalkori; PF 2341066 912279-98-2 PF-2341066 PF2341066 02341066 tyrosine RTK ALK anaplastic lymphoma kinases c-MET inhibitors inhibits inhibition hepatocyte growth factors receptors antitumors non-small lungs cancers anaplastic large lymphoma neuroblastoma fusion proteins cMET lower back pains GABAA receptors skeletal muscles relaxant 24.219656230816
14747 Cucurbitacin I 2222-07-3 ≥98% 2013-08-05 8.619796983601 cucurbitacin-i Elatericin B; JSI-124; NSC 521777 204376-97-6 STAT3/JAK signalings pathways triterpenoids STAT3 JAK2 JSI-124 cancers tumors growths STAT-3 STATs three signals JAK-2 JAKs JAK twos JSI124 JSI 124 tyrosine phosphorylated V-Src NIH 3T3 NIH3T3 NIH-3T3 A549 A-549 As 549 DNA bindings binds genes transcriptions cucurbitacin-I dendritic macrophages immunotherapy clonogenicity nasopharyngeal carcinoma NPCs in vitro NSCs 521777 NSC521777 NSC-521777 elatericin-B elatericins b intracellular DNA 8.619796983601
14931 CUR 61414 New 334998-36-6 ≥98% 2013-11-01 43.127448854756 cur-61414 G-856 570431-20-8 inhibitors signal transduction cancers receptor antagonists inhibits inhibitions CUR61414 CUR-61414 CURs 61414 potent hedgehogs HH hedgehog-induced induced activity active cellular binds binders bindings pathway smoothened activator Smo smooth proliferation basal carcinoma regression basaloid lesions ultraviolet lights skin Gs 856 G856 43.127448854756
81025 Curcumin 458-37-7 ≥90% 10.503295676314 curcumin Indian Saffron; Turmeric yellow anti-oxidant anti-imflammatory NOS nitric oxide synthase 10.503295676314
81025.1 Curcumin (technical grade) 458-37-7 ≥65% 3.881114537808 curcumin-technical-grade Indian Saffron; Turmeric yellow anti-oxidant anti-imflammatory NOS nitric oxide synthase 3.881114537808
10011388 Cu/Zn SOD (human) Polyclonal Antibody - 23 kDa 2008-04-03 126.698163227059 cu-zn-sod-human-polyclonal-antibody Cu/Zn Superoxide Dismutase; SOD1 SOD1 SOD2 SOD3 EC-SOD oxidative stress ROS superoxide antibodies antiserum WB western blots immunoblotting IP EIA IHC immunohistochemistry neurochemistry immunoprecipitation enzyme immunoassays neurochemistry blotting 126.698163227059
14803 Cyanidin chloride 528-58-5 ≥98% 2013-09-17 9.186434965094 cyanidin-chloride Cyanidol chloride; IdB 1027 natural products antioxidants oxidative injury inflammation cancers obesity diabetes inflammatory anthocyanidins fruits vegetables flavonoids vasoprotective carcinogenesis cyanidine 9.186434965094
14748 Cyclic Pifithrin-α (hydrobromide) 511296-88-1 ≥95% 2013-08-16 6.915073264472 cyclic-pifithrin-hydrobromide Cyclic PFT-α; Pifithrin-β; PFT-β 60477-34-1 inhibitors cancers neurosciences intracellulars signalings apoptosis cells biology signals transductions autophagy inhibits inhibitions pifithrins pifithrin-a pifithrin-alpha pifithrin-.alpha. pifithrin-α pifithrin-beta pifithrin-β pifithrin-.beta. pifithrin-b β α beta alpha .beta. .alpha. b a h2O2 IGROV-1 IGROV1 IGROV 1 one A2780 A-2780 A 2780 HCT-116 HCT116 HCT 116 H460 H 460 H-460 antimicrotubules anti-microtubule anti microtubule DNA damages UV ultraviolet radiation melanocytes p53 transcription hydrogen peroxide H2O2 growth 6.915073264472
11321 Cyclopamine 4449-51-8 ≥98% 2012-02-20 31.120965316145 cyclopamine 11-Deoxojervine; Jervine 11051-96-0 26108-61-2 veratraman 11-deoxyjervine 11 deoxyjervine hedgehogs development teratogen cancers smoothened inhibitors cyclopia genes expressions signal transduction inhibits inhibition signaling steroids alkaloids pathways pax7 31.120965316145
13849 Cyclophosphamide (hydrate) 6055-19-2 ≥98% 2013-04-24 8.887570860058 cyclophosphamide-hydrate Endoxan 50-18-0 cancers autoimmune diseases alkylating agents treats treatments nitrogen mustard autoimmune disorders prodrug pro-drug pro drugs DNA deoxy ribonucleic acids cancers cells aldehydes dehydrogenases ALDHs cyclophosphamides metabolizes phosphoramides deaths apoptosis 8.887570860058
14745 Cysmethynil 851636-83-4 ≥98% 2013-08-06 4.220206293819 cysmethynil Icmt Inhibitor isoprenylcysteines carboxyl methyltransferases Icmts prenylation inhibitors inhibits inhibitions autophagy cancers post-translational modifications cells signaling methylation signals modify indole-based indoles based time-dependent times dependent substrates S-adenosylmethionine adenosylmethionine treatments Ras carboxylmethylation pathways PC3 prostates G1 phases G-1 Gs 1 one autophagy-mediated autophagy mediated deaths proteins 4.220206293819
11328 Cytochalasin B 14930-96-2 ≥98% 2012-02-22 18.175235464351 cytochalasin-b NSC 107658; Phomin 11032-95-4 11042-65-2 16006-03-4 21476-12-0 inhibitors actin proliferation migration phagocytosis glucose exocytosis cells division chemotaxis inhibits inhibition mycotoxins polymerization NSC-107658 NSC107658 18.175235464351
11329 Cytochalasin C New 22144-76-9 ≥99% 2014-01-24 0.186740331491 cytochalasin-c inhibitors cells biology cytoskeletal research cytochalasins actin filaments polymerization cancers inhibitions inhibits polymerizes movements growths phagocytosis degranulation secretions cultures mice mouse D 11044-50-1 0.186740331491
11330 Cytochalasin D 22144-77-0 ≥95% 2013-06-25 13.383186003683 cytochalasin-d NSC 209835 11032-97-6 25852-72-6 28455-04-1 69401-32-7 zygosporin-A zygosporins A inhibitors cancers cells biology cytoskeletal research inhibits inhibitions cytochalasins D cell-permeable cells permeables filaments polymerizations prevents migrations tumors cells cytochalasin-d NSC-209835 NSCs 209835 NSC209835 fungal fungus fungi metabolites actins movements growths phagocytosis cellular eating drinking degranulations secretions 13.383186003683
11331 Cytochalasin E 36011-19-5 ≥98% 2012-07-24 5.558107734806 cytochalasin-e 12623-99-3 actin polymerization cytoskeleton inhibitors angiogenesis cancer cells biology inhibitions inhibits epoxide-containing epoxide analogs cytochalasin-b cytochalasin b endothelial impairment impairing impairing angiogenesis tumors growth cytochalasin-e 5.558107734806
10004600 Cytokeratin Monoclonal Antibody (Clone C-11) - 2008-06-05 3.456055248618 cytokeratin-monoclonal-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera isoforms western blots WB flow cytometry FC immunocytochemistry ICC immunohistochemistry IHC immunoblotting proteins blotting 3.456055248618
10568 Cytokeratin Monoclonal APC Antibody (Clone C-11) - 2011-03-04 1.940355169692 cytokeratin-monoclonal-apc-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera isoforms flow cytometry FC proteins immunofluorescence IF 1.940355169692
10349 Cytokeratin Monoclonal FITC Antibody (Clone C-11) - 2010-04-14 2.020193370165 cytokeratin-monoclonal-fitc-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera isoforms western blots WB flow cytometry FC immunofluorescence IF immunoblotting proteins blotting 2.020193370165
10478 Cytokeratin Monoclonal PE Antibody (Clone C-11) - 2010-10-28 0.943646408840 cytokeratin-monoclonal-pe-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera anti-serum anti serum anti-ser anti sera isoforms flow cytometry FC immunoblotting proteins blotting IF immunofluorescence 0.943646408840
63500 Cytotrienin A 189010-85-3 ≥95% 2009-07-06 14.892928176795 cytotrienin-a anti-tumor anti-cancer apoptosis ROS caspace-3 p36 MBP kinase JNK 14.892928176795
13305 D 4476 301836-43-1 ≥98% 2009-07-29 22.931652788740 d-4476 Casein Kinase I Inhibitor inhibitors inhibits inhibition casein kinases 1 CK1 Ck1δ TGF-β TGFβ type-1 receptors ALK5 PKD1 p38α MAPK kinases phosphorylation FOXO1a RhoB p53 Smad3 D4476 22.931652788740
13202 Daidzin 552-66-9 ≥98% 2011-09-30 7.449760589318 daidzin Daidzoside; NPI 031D isoflavones soy kudzu anti-oxidants cancers oxidants stress atherosclerosis inhibitor inhibits inhibition mitochondrial aldehydes dehydrogenases 2 alcohols plants anticarcinogenic anti-carcinogenic anti carcinogenic antioxidants antidipsotropic dipsotropic anti-dipsotropic anti-atherosclerosis antiatherosclerosis atherosclerosis 1329-08-4 28572-56-7 NPI-031D NPI031D 7-glucoside glucosides 7.449760589318
11498 Dasatinib 302962-49-8 ≥98% 2013-10-18 28.529762139662 dasatinib BMS 354825; Sprycel inhibitors inhibits inhibitions cancers kinases receptors non nonreceptors non-receptor tyrosines fibrosis drugs resistance signals transductions potent Abl Src Lck therapeutic diseases fibrotic BMS-354825 BMS354825 BMS 354825 spyrcel 35482513 28.529762139662
14159 Daunorubicin (hydrochloride) 23541-50-6 ≥98% 2013-04-10 5.601823204420 daunorubicin-hydrochloride NDC 0082-4155; Ondena; RP 13057 daunomycin antitumors antibiotics acute myeloid leukemia AMLs apoptosis drugs resistance anticancers anti-cancers anti cancers induces apoptosis U937 HL-60 HL60 HLs 60 cells tiggers ROS dependent sphingomyelin ceramide pathways DNA binding binds AP1 AP-1 AP 1 HCL 20830-81-3 52471-42-8 1087700-63-7 cerubidine daunoblastin chlorohydrate NDC0082-4155 NDC-0082-4155 NDC00824155 NDC-00824155 NDCs 00824155 00824-155 RP-13057 RP13057 Ribidomycin 5.601823204420
15318 DBeQ New 177355-84-9 ≥98% 2014-01-16 92.222222222222 dbeq N,N'-Dibenzylquinazoline-2,4-diamine; JRF 12 AAA ATPase p97 inhibitors endoplasmic reticulum-associated reticulum associated degradation ERAD autophagy caspase-3 caspase -7 cancers ubiquitin-proteasome systems ubiquitin proteasome caspases autophagy apoptosis selective reversible ATPs JRFs 12 JRF12 JRF-12 92.222222222222
160755 DcR2 Polyclonal Antibody - 0E-12 dcr2-polyclonal-antibody TRAIL-R4; TRUNDD apoptosis cell death TNF DR4 DR5 DcR1 TRID TRAIL antibodies western blots blotting WB antisera antiserum immunoblotting 0E-12
10005432 DDA 25152-84-5 ≥98% 2004-07-22 11.094386740331 dda Decadienealdehyde; trans-2,4-Decadien-1-al lipoxygenases diatoms alkyls linoleic acids dihomo-gamma-linolenic dihomo-g-linolenic arachidonic dihomo-.gamma.-linolenic carcinoma Caco2 apoptosis 11.094386740331
11166 Decitabine 2353-33-5 ≥98% 2012-02-27 21.106777163904 decitabine DAC; NSC 127716; 5-aza-2’-Deoxycytidine; Dacogen β-decitabine 105597-46-4 123795-43-7 5-azadeoxycytidine 5-azadCyd 5-aza-CdR inhibitors inhibitions inhibits epigenetics DNA methylation genes expression methyltransferases hypomethylation mutagenic regulations 21.106777163904
10010706 (−)-Deguelin 522-17-8 ≥98% 2008-09-18 15.421546961326 -deguelin (-)-cis-Deguelin rotenoids flavonids cancers antiproliferative chemoprevention parkinsons diseases Akt PKB PI3K COX-2 COX2 apoptosis PI3-K 15.421546961326
11012 Delphinidin chloride Exclusive 528-53-0 ≥97% 2012-03-06 31.773040583162 delphinidin-chloride Ephdine diseases cancers cardiovascular tyrosines kinases vasorelaxation smooth muscles chlorides Cl vasorelaxants inhibitors inhibition inhibits EGFRs epidermal epidermis growth factors receptors HATs histones acetyltransferases anthocyanidins plants pigments anthocyanins blue red colors flowers fruits wines nitric oxides NOs vascular endothelium signaling signalling epithelial estrogens ERa ERalpha ER.alpha. ERα apoptosis cells death autophagy phagocytosis delphinidol 13270-61-6 IdB 1056 IdB-1056 31.773040583162
9001536 Deltarasin (hydrochloride) New 1440898-82-7 ≥98% 2014-03-04 0E-12 deltarasin-hydrochloride 1440898-82-7 1440898-61-2 KRAS oncogene PDEδ PDE.delta. PDEdelta PDEd PDE δ .delta. delta d inhibitors inhibits inhibitions RAS pancreatic cancers cells signaling signals RAS humans pancreatic pancreas ductal adenocarcinoma Panc-Tu-I tumors mice mouse carcinoma xenografts intracellular transduction HCl 0E-12
10961 Demethoxycurcumin 22608-11-3 ≥98% 2011-09-23 13.493611775377 demethoxycurcumin DMC curcumin cancers transcription genes expressions p300 Wnt/β-catenin iNOS inflammation proliferation cells p300 coactivator inhibits lipopolysaccharides inhibitor inhibition 13.493611775377
700390 Demethylase (Jumonji-type) Activity Assay Kit - 2010-05-26 15.391020257827 demethylase-jumonji-type-activity-assay-kit kits assays measures measurements histones nucleoproteins chromatins DNA deoxynucleic acids eukaryotic nucleus nucleosomal H3 H4 H2B H2A octamers amino termini acetylation phosphorylation ubiquitination methylation replication repair transcriptional activation repression dysregulation tumors suppressor genes cancers inhibitors enzymes catalyzes epigenetic marks methyls lysines arginines residues demethylases 1 JMJC JHDM1 JHDM2 JHDM3 JARID1 UTX/UTY cupin 2-oxoglutarate 2OG iron Fe(II) oxygenases hydroxylation JMJD2A JMJD2B JMJD2C JMJD2D JMJD2E JMJD2F fluorescence-based fluorescent cells lysates formaldehydes peptides substrates oxidation/decarboxylation acetoacetanilides ammonia H3K9(Me)3 15.391020257827
700400 Demethylase (LSD-type) Activity Assay Kit - 2010-08-05 13.990534069981 demethylase-lsd-type-activity-assay-kit kits assays measures measurements histones proteins nucleoproteins chromatins structures DNA deoxyribonuclease eukaryotics nucleus nucleosomals core particles H3 H4 H2B H2A octamers amino termini post-translationally acetylation phosphorylations ubiquitination methylations replication repair transcriptional activation repression dysregulation tumor suppressor genes cancers enzymes catalyze epigenetic marks therapeutics drugs development lysine-specific demethylases LSD1 KDM1 p110b BHC110 NPAO LSD2 flavin adenines dinucleotides FAD-dependent amines oxidases monoamines MAOs polyamines PAOs demethylates monomethylateds dimethylateds lysines 4 K4 repression deacetylases co-repressor complexes 1/2 CtBP neuronal CoREST p53 LYS370 53BP1 apoptosis C-terminal domains CW-type zinc finger motif zince-binding sites chromatin-remodeling fluorescence-based formaldehyde N-terminal tail acetoacetanilides ammonia 13.990534069981
10165 D-erythro-MAPP 143492-38-0 ≥98% 2004-02-23 13.221390423573 d-erythro-mapp (1S,2R-D-erythro-2-N-myristoylamino)-1-phenyl-1-propanol ceramides inhibitors sphingolipids HL60 HL-60 cancer cells G0/G1 G0-G1 inhibits ceramidase 13.221390423573
14632 Dexrazoxane 24584-09-6 ≥98% 2013-06-20 7.739116157334 dexrazoxane ICRF 187; Totect®; Zinecard; NSC 169780 ICRF-187 ICRF187 ICRF 187 doxorubicin cancers cardiotoxicity irons chelators inhibitors inhibits inhibitions topoisomerase IIα anthracycline-induced antioxidant free radicals scavengers anthracycline induced induces intracellular reducing reduces reducer cardiotoxicity extravasation injury injuries hydroxyl superoxides lipids DPPH ABTS NSCs 169780 NSC-169780 NSC169780 ADR529 ADRs 529 ADR-529 savene oxidative cardiology 2,2’-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) diphenylpicrylhydrazyl 7.739116157334
10012577 Diallyl Trisulfide 2050-87-5 ≥95% 2009-04-07 8.413363259668 diallyl-trisulfide NSC 651936; DATS garlic hydrogen sulfides H2S cancers tumors smooth muscle cholesterol atherosclerosis donors supresses colon synthesis genes expression adenocarcinomas HCT-15 cells PC-3 xenografts 8.413363259668
10009081 Didox Exclusive 69839-83-4 ≥98% 2007-01-16 15.862636148381 didox antioxidants hydroxamic acids apoptosis cancers cells polyhydroxylated aromatic ocidative injury brains HIV dementia bcl-2 15.862636148381
10006876 Diethylstilbestrol 56-53-1 ≥98% 2005-10-03 4.815292817679 diethylstilbestrol synthetics receptors agonists pregnant pregnancies linked breasts cancers congenital abnormalities abnormality offspring 3H-estradiols binding affinities affinity sexes hormones globulins SHBG estrogens 4.815292817679
10009986 Dimethoxycurcumin 160096-59-3 ≥90% 2007-08-03 15.900365094417 dimethoxycurcumin curcumins cancers ASCJ9 antitumors anti-tumor phytochemicals turmeric inhibits inhibition inhibitory growth expression cells ASC-J9 15.900365094417
14707 Dinaciclib New 779353-01-4 ≥98% 2013-12-05 54.418712280521 dinaciclib SCH 727965 1000697-89-1 Sch 727965 Sch727965 Sch-727965 SCH 727965 anticancers anti-cancers anti cancers cyclin-dependent pan CDKs pan-CDK inhibitors CDK1 CDK2 CDK5 CDK9 flavopiridol cyclin dependent kinases CDK-1 CDK-2 CDK-5 CDK-9 1 2 5 9 one two five nine in vitro inhibits inhibitions tumors growths ovarian carcinoma potent 1000697-89-1 DNA synthesis 54.418712280521
15303 Disulfiram New 97-77-8 ≥95% 2014-02-18 0E-12 disulfiram NSC 25953; Tetraethylthiuram disulfide 155-​01-​1 11078-​22-​1 Antabuse Antabus alcoholism alcohol abuse dependence metabolism anti-cancer anti cancers anticancers metal chelator copper zinc 20S proteasome 26S proteasome cocaine inhibitors inhibits inhibitions aldehydes dehydrogenase dopamine β-hydroxylase irreversible b-hydroxylase beta-hydroxylase .beta.-hydroxylase MDA-MB-0231 MDAMB0231 MDA MB 0231 breast reactive oxygen species ROS JNK p38 NF-kB NF-B NF-kappaB NF-.kappa.B stem cells abstensil abstinil abstinyl accel TET TET-R TETR R akrochem TETD alcophobin antadix antaethyl antalcol antetan antetil anticol antietanol antietil antikol antivitium aversan averzan contralin cronetal dicupral ekagom DTET TEDS TETDS espenal etabus ethyl thiram thiurad tuads tuex etiltox exhoran exhorran hoca krotenal tetraethyldithiuram disulfide NSCs 25953 NSC-25953 NSC25953 nocceler TET-G TETG G noxal refusal sanceler soxinol stopetyl TTs tetradin tetradine tetraethyldithiuram tetraethylthioperoxydicarbonic diamide tetraethylthiram tetraethylthiuram tetraetil teturam teturamin thiuram E thiuranide 0E-12
10005276 DL-threo-PDMP (hydrochloride) 80938-69-8 ≥98% 2004-08-10 4.107771639042 dl-threo-pdmp-hydrochloride analogs analogues inhibits inhibitors inhibition cytotoxicity glucosylceramides synthases chirality stereoisomers sphingosine 4.107771639042
71210 DMOG 89464-63-1 ≥98% 136.578003683241 dmog Dimethyloxallyl Glycine nuclear receptors cancer hypoxia HIF-1alpha Hif1α HIF-1α HIF1α Pro-angiogenic proangiogenic factors HIF-PH HIFPH prolyl hydroxylase inhibits inhibitors inhibition 136.578003683241
14617 DMXAA 117570-53-3 ≥98% 2013-06-21 0E-12 dmxaa NSC 640488; Vadimezan; 5,6-Dimethylxanthenone-4-acetic Acid; ASA 404 inhibitors inhibits inhibitions cancers immunology angiogenesis signals transductions apoptosis xanthene vasculars agents disrupting apoptosis endothelium necrosis tumors cores TANKs bindings binds binders kinases 1 TBK1 TBK-1 TBKs 1 interferone factors regulatory 3 IRF3 IRFs 3 IRF-3 growths VEGF VEGFR-1 VEGFR-2 1 2 ASA404 ASA-404 ASAs 404 dimethylxanthenone acetic acids ASA1404 ASA-1404 1404 NSC640488 NSC-640488 signaling pathways leukocytes type I interferons kinases endothelial cells NSC640488 NSC-640488 0E-12
10009851 D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) - >98% 2007-06-04 8.384281767956 d-myo-inositol-1-3-4-5-6-pentaphosphate-ammonium-salt Ins(1,3,4,5,6)P5; 1,3,4,5,6-IP5 (sodium salt) inositols phosphate IP5 signal transduction InsP phosphitidylinositol phospholipase C PLC phosphioinositide 3-kinase PI3-K Akt cancer angiogenesis PKB protein kinase B 8.384281767956
660990 DNA Laddering Kit - 7.808839779006 dna-laddering-kit kits assays apoptosis 7.808839779006
589324 DNA Methylation EIA Kit - 2009-04-23 109.027306629834 dna-methylation-eia-kit 5-Methyl-2'-deoxycytidine ELISA Kit solid plates DNA deoxyribonucleic acids CpG islands dinucleotides genes genomes cancers genomic hypomethylation hypermethylation tumors suppressors malignancy carcinogenesis plasma blood urine leukemia tissues differentiation aging methyltransferases DNMTs DNMT1 DNMT3a DNMT3b nucleosides analogs azacitidine decitabine zebularine drugs suppression competitive assays EIAs ELISAs culture supernatants sample matrices 109.027306629834
13479 DNA Methyltransferase 1 Monoclonal Antibody (Clone 60B1220.1) - 2009-06-29 2.611602209944 dna-methyltransferase-1-monoclonal-antibody-clone-60b1220-1 DNMT1 WB Western blots immunoblotting IHC ChIP IP DNMT 1 blotting immunohistochemistry immunoprecipitation 2.611602209944
13481 DNA Methyltransferase 2 Monoclonal Antibody (Clone 102B1259.2) - 2009-07-13 1.320047355959 dna-methyltransferase-2-monoclonal-antibody-clone-102b1259-2 DNMT2 WB Western blots immunoblotting DNMT-2 monoclonals blotting DNMT 2 blotting 1.320047355959
13480 DNA Methyltransferase 2 Polyclonal Antibody - 2009-07-13 1.729957028852 dna-methyltransferase-2-polyclonal-antibody DNMT2 WB Western blots immunoblotting DNMT 2 blotting DNMT-2 1.729957028852
13483 DNA Methyltransferase 3a Monoclonal Antibody - Biotinylated (Clone 64B814.1) - 2009-07-15 2.783346487766 dna-methyltransferase-3a-monoclonal-antibody-biotinylated-clone-64b814-1 DNMT3a ELISA DNMT3a Enzyme-linked immunosorbent assays 2.783346487766
13484 DNA Methyltransferase 3a Monoclonal Antibody (Clone 64B1446) - 2009-07-15 1.320047355959 dna-methyltransferase-3a-monoclonal-antibody-clone-64b1446 DNMT3a WB Western blots immunoblotting DNMT3a blotting ICC immunocytochemistry IHC immunohistochemistry 1.320047355959
13482 DNA Methyltransferase 3a Monoclonal Antibody (Clone 64B814.1) - 2009-07-01 3.813198281154 dna-methyltransferase-3a-monoclonal-antibody-clone-64b814-1 DNMT3a WB Western blots immunoblotting DNMT3a blotting ICC immunocytochemistry 3.813198281154
13485 DNA Methyltransferase 3b Monoclonal Antibody (Clone 52A1018) - 2009-07-01 5.301227747084 dna-methyltransferase-3b-monoclonal-antibody-clone-52a1018 DNMT3b WB Western blots immunoblotting DNMT3b immunoprecipitation immunofluorescence immunocytochemistry ChIP immunohistochemistry IHC IP ICC IF blotting 5.301227747084
10770 DNA Methyltransferase 3L (human recombinant) - ≥95% 2011-06-08 4.881645181092 dna-methyltransferase-3l-human-recombinant DNMT3-Like Protein; DNMT3L DNA methyltransferases s-adenosylmethionine CpG methylation lysines proteins DNMT3a DNMT3b histones cysteine ADD PWWP mTase 4.881645181092
589320 DNA/RNA Oxidative Damage EIA Kit - 2008-05-21 686.129682478087 dna-rna-oxidative-damage-eia-kit 8-OH-2dG; 8-OH-DG; 8-hydroxy-2'-Deoxyguanosine; DNA/RNA Oxidative Damage ELISA kits EIAs mass spectrometry enzymes immunoassays elisas 8-OH-2-dG 8-OH-2'-dG 8OH2'dG 8OH2dG 8OH2d 8 oxo 8-oxo deoxyguanine deoxyguanosine hydroxy ohdg 2 EIA/ELISA assays 8-ohdg 8ohdg 8-hydroxy-2-deoxy guanosine immunosorbents 8-hydroxy-2'-dg 8-OH-2'-deoxyguanosine 8-OH-2-deoxyguanosine assays solid plates injury stress aging cancers oxidations diabetes DNA deoxyribonucleic ribonucleic acids diseases states guanines repair urine ribose-free bases nucleosides 8-oxo-guanine 8-hydroxyguanine 8-oxo-guanosine 8-hydroxyguanosine metabolites age-related cells cellular oxidized hydroxyl radicals peroxynitrite plasmas cells lysates tissues liquid chromatography mass-spectrometry LC-MS 686.129682478087
10006305 D-NMAPPD Exclusive 35922-06-6 ≥98% 2005-02-23 19.413057090239 d-nmappd (1R,2R)-B13; CAY10466 ceramides inhibitors cancers cells inhibits inhibition ceramidase apoptosis colorectal keratinocytes melanoma lines viability inducers induces 19.413057090239
11637 Docetaxel 114977-28-5 ≥98% 2012-05-17 11.459318600368 docetaxel RP 56976; Taxotel; NSC 628503 129522-72-1 216252-50-5 docetaxol taxol cancers breasts prostate cells proliferation microtubules replication hormones hormone-refactory refractory NSC628503 NSC-628503 RP56976 RP-56976 docetere taxotere 11.459318600368
11967 Dorsomorphin 866405-64-3 ≥98% 2013-06-03 32.401915285451 dorsomorphin Compound C compound-C inhibitors inhibits inhibitions AMPKs bones morphogenetics proteins types 1 type-1 ones receptors BMP ACTR-I ACTRs ACTRI ACRTs I ALK2 BMPR-IA ALK3 BMPR-IB ALK 6 Akt/mTOR autophagy cancers ALKs ALK-2 ALK-3 ALK-6 2 3 6 two three six BMPRIA BMPR s IA IB BMPRIB Akt mTOR potent selective reversible activity kinases doses denpendents dose-dependently dose-dependents downregulate pathways induces U251 humans glioma cells U-251 U 251 32.401915285451
10354 Dot1L (human recombinant) - ≥95% 2012-08-02 7.514759273875 dot1l-human-recombinant Dot1-like; Disruptor of Telomeric Signaling 1-Like methyltransferases epigenetics H3K79 histones histone 3 lysine 79 MLL-rearranged leukemias Dot 1L Dot-1L Dot1-L Dot1 L Dot 1 L KMT4 Histone H3K79 methyltransferase DOT1 DOT-1 DOT 1 KIAA1814 KIAA-1814 KIAA 1814 Lysine N-methyltransferase 4 H3K79 HMTase EC 2.1.1.43 7.514759273875
15220 Dovitinib New 405169-16-6 ≥98% 2013-11-18 33.177171295150 dovitinib 804551-​71-​1 TKI258 TKIs 258 TKI-258 CHIRs CHIR-258 CHIR258 receptors tyrosines kinases inhibitors inhibits 804551-71-1 inhibitons proteins angiogenesis vascular endothelial growth factors VEGFR basic fibroblasts bFGFR platelet-derived platelet derived PDGFR anticancers anti-cancer anti cancers antiangiogenic angiogenic anti-angiogenic hepatocellular carcinoma HCC multi-targeted multi targeted PDGFb PDGFbeta PDGF.beta. PDGF-β PDGF-b PDGFβ PDGF-beta PDGF-.beta. PDGFs β b beta .beta. dovitinib targets factor-2 VEGFR-2 2 factor-1 signals impairing impair prevents motility pancreatic cells lines HPAF-II BxPC-3 MiaPaCa2 L3.6pl HPAF II BCPC 3 L3 6pl proliferation effects mechanisms metastasis clinical trials treatments advanced solid tumors 33.177171295150
15007 Doxorubicin (hydrochloride) 25316-40-9 ≥98% 2013-04-18 26.035905840084 doxorubicin-hydrochloride DOX; NSC 123127; Adriacin 23214-92-8 23257-17-2 24385-08-8 25311-50-6 29042-30-6 1394125-92-8 anthracyclines antitumors antibiotics inhibitors DNA topoisomerases II damage apoptosis p53 anti-tumors tumors anti anti-biotics biotics inhibits inhibitions nucleic acids induces suppressors proteins ADM Hcl ADR adriablastina CS adriablastin-CS Adriamycin adriblastin adriblastina adriblastina RD adriblastina-RD FI-106 FI 106 FI106 FI-6804 FI 6804 FI6804 Lipo-DOX LipoDOX lipo hydroxydaunorubicin NSC123127 NSC-123127 NSCs 123127 deoxyribonucleic induces induced cells deaths double-stranded dsDNA breaks breakages intercalating intercalations accumulations 26.035905840084
700210 DPP (IV) Inhibitor Screening Assay Kit - 2009-05-27 92.535672191528 dpp-iv-inhibitor-screening-assay-kit Dipeptidyl exopeptidases IV DPPIV DPP4 enzymes CD26 cluster of differentiation T-cells activation antigens adenosine deaminase complexing 2 membrane-bound glycoproteins immune regulation signal transduction apoptosis kidneys small intestines placentas humans serums seminal fluids proteolytic derivatives serines X-prolines X-alanines dipeptides N-terminus N-terminal polypeptides growth factors chemokines neuropeptides vasoactive inhibitors inhibits inhibition oral antidiabetic agents glucose homeostasis glucoregulatory hormones glucose-dependent insulinotropics GIP glucagon-like peptide-1 GLP-1 gastric therapeutics Type 2 tumors cancers markers neoplasms assays kits measures measurements fluorescences fluorescent fluorogenics substrates Gly-Pro-Aminomethylcoumarin AMC 92.535672191528
62237 DPPP 110231-30-6 ≥98% 2006-07-25 52.226372007366 dppp Diphenyl-1-pyrenylphosphine hydroperoxides oxidative stress injury fluorescence fluorescent lipids cholesterols LDL oxidation DPPPO DPPP=O atherosclerosis 52.226372007366
11178 DPY-30 (human recombinant) - ≥95% 2012-01-05 5.858724259166 dpy-30-human-recombinant hDPY-30; SAF19; DPY-30-like protein epigenetics methyltransferase histones H3K4 genes regulations MLL proteins subunits Ash2L MLL sore complex DPY30 methylation C. elegans XX mutations XO growth development homodimer monomers WDR5 WDR-5 WDR 5 RbBP5 basal rates DPY-30L DPY30L hDPY30 SAF-19 5.858724259166
10010302 DRB 53-85-0 ≥98% 2008-01-21 3.077486187845 drb NSC 401575; Benzimidazole cancers HIV P53 apoptosis Cdk7 Cdk9 CTD CKI CKII adenosine inhibitors inhibits inhibition transcription RNA polymerase cell cycles adenocarcinoma transactivator tat 3.077486187845
10007963 E-64 66701-25-5 ≥98% 2009-11-12 10.013272107295 e-64 inhibitors cysteine proteases cathepsins papain calpain irreversible inhibition inhibited E64 E 64 10.013272107295
10007964 E-64c 76684-89-4 ≥98% 2006-08-02 12.719516574585 e-64c NSC 694279; Loxistatin Acid; EP 475 E-64 cysteine protease cell cycle inhibitor E-64d 12.719516574585
13533 E-64d 88321-09-9 ≥98% 2010-08-16 28.407082872928 e-64d Aloxistatin; E-64c ethyl ester; Loxistatin; NSC 694281; EST; EP 453 cysteine protease proteins degradation lysosome inhibitors inhibits inhibition calpain cathepsin E64d E 64d 64 207396-71-2 cells cancers carcinomas A431 E-64d Morphinans 28.407082872928
10005732 EAF2 Blocking Peptide - >75% 2004-09-01 0E-12 eaf2-blocking-peptide U19; ELL-Associated Factor 2 WB western blots blotting IHC immunohistochemistry immunoblot formalin-fixed paraffin-embedded sections apoptosis inhibits ihibitors inhibition prostate tumors testosterone antibodies paraffins signaling signalling controls peptides 0E-12
10005190 EAF2 Polyclonal Antibody - 2004-08-12 1.127060773480 eaf2-polyclonal-antibody U19; ELL-Associated Factor 2 WB western blots blotting IHC immunohistochemistry immunoblots formalin-fixed paraffin-embedded sections apoptosis inhibits inhibitors inhibition prostate tumors testosterone suppressive supression leukemogenesis cancers endocrinology immunoblotting 1.127060773480
14183 EBPC 4450-98-0 ≥98% 2013-03-18 15.185185185185 ebpc NSC 229530 metabolisms metabolic syndromes enzymes activity activities glucose diabetes PGF2α synthases aldoses reductases AKR1B1 sorbitol inhibitors drugs resistances cancers inhibits inhibitions improve cytotoxic effects anti-cancer anti cisplatin HeLa cervical carcinomas prostaglandins PGE2 potent NSC-229530 NSC229530 humans enzymes polyol pathways IL-1β IL-1.beta. IL-1B interleukins interleukin-1β interleukin-1B expressions diabetes chemotherapy chemotherapeutics in vitro doxorubicin cisplatin cells endometrial 15.185185185185
11049 Echinomycin 512-64-1 ≥98% 2012-03-21 3.759668508287 echinomycin Antibiotic A 654I; NSC 526417; Quinomycin A; SK 302B; NSC 13502 11016-61-8 NSC13502 NSC526417 NSC-13502 NSC-526417 SK302B SK-302B hypoxia HIF-1 cancers neuroscience VEGF inhibitors inhibits inhibition genes expression glycolysis angiogenesis migration invasion cells DNA HIF-1α HIF-1β U215 hippocampal neurons myeloma melphalan 3.759668508287
14168 ECT2 BRCT domains (human recombinant) New - ≥95% 2014-01-07 95.277777777777 ect2-brct-domains-human-recombinant Epithelial Cell-transforming Sequence 2 Oncogene ECT2 Protein-Protein interactions (PPIs) DNA damages responses BRCT domains cancers Guanine nucleotides exchanges factors GEFs ECT-2 ECTs 2 epithelial cells transforming sequences 2 oncogenes guanines GDPs GTPs GTPases rho family RhoA RhoC Rac1 Cdc42 glioma cancers cytoskeletal research proteins cycles cytokinesis protein-DNA BRCA1 p53 binding RAD9 95.277777777777
10628 EED (human recombinant) - 95 2010-12-03 49.481837165968 eed-human-recombinant Embryonic Ectoderm Development EEDs histones modifications epigenetics chromatin research proteins recombinant cancers genes regulations bindings binders binds methyltransferase human embryonic ectoderm developments WD40 WD-40 WDs 40 49.481837165968
15363 EGFR Inhibitor New 879127-07-8 ≥98% 2014-02-13 0E-12 egfr-inhibitor Epidermal Growth Factor Receptor Inhibitor EGFR inhibitors inhibits inhibitions substituted pyrimidine kinases tyrosine L858R L861Q mutants apoptosis cell permeable selective antagonists signals transductions biochemistry proteins intracellular signals signaling cancers 0E-12
15137 eIF4E (human recombinant) New - ≥90% 2014-02-28 0E-12 eif4e-human-recombinant mRNA Cap-binding Protein; Eukaryotic Translation Initiation Factor 4E; eIF-4F 25 kDa subunit Translations mRNA 5'-cap cancers inititaion factors MCM eukaryotic messengers RNA mRNA four F 4E E caps structures proteins synthesis mnk1 mitogen activated mitogen-activated kinases kinase-interacting interacting oncogene oncogenic humans malignancy malignancies breast colon heads necks carcinomas cells biology recombinant 0E-12
15564 eIF4E (human recombinant; GST-tagged) New - ≥85% 2014-02-28 0E-12 eif4e-human-recombinant-gst-tagged Eukaryotic Translation Initiation Factor 4E; mRNA Cap-binding Protein; eIF-4F 25 kDa subunit translations mRNA 5'-cap cancers initiation factors eukaryotic messengers RNA mRNA four F 4E E caps structures proteins synthesis mnk1 mitogen activated mitogen-activated kinases kinase-interacting interacting oncogene oncogenic humans malignancy malignancies breast colon heads necks carcinomas cells biology recombinant 0E-12
10569 Ellagic Acid 476-66-4 ≥95% 2010-10-13 11.725082872928 ellagic-acid Gallogen; TBBD; Lagistase polyphenols, antioxidants, cancers inflammation cytochrome P450s CYP450 epigenetics genes expression histones modifications alizarin yellow G 91006 elagostasine 77415-21-5 124590-32-5 PRMTs inflammatory anti-carcinogenic anti-mutagenic organ-preserving antimutagenic antiinflammatory Acid Benzoaric Benzoaric Acid Acid Ellagic Ellagic Acid 11.725082872928
11838 Embelin 550-24-3 ≥95% 2012-10-01 1.106077348066 embelin NSC 91874 embelic acid emberine natural products cancers inflammation NF-κB apoptosis caspases XIAP inhibits inhibitors inhibitions benzoquinone plants Embelia binds cells inflammation IKK NFκB NF κB NF-kappaB NF-.kappa.B NFkappaB NF.kappa.B X linked inhibitor apoptosis X-linked 1.106077348066
13109 Emodin 518-82-1 ≥98% 2012-09-20 2.160110497237 emodin NSC 622947; Archin; NSC 408120; Frangulic Acid; Schuttgelb emodol frangula rheum NSC408120 NSC-408120 NSC622947 NSC-622947 natural products cancers inflammation estrogen receptors apoptosis dyslipidemia receptors agonists CSN ER anthraquinone plants suppression inhibits inhibition inhibitors casein kinases II tumors suppressors p53 phytoestrogen CK II 2.160110497237
15382 Enniatin B New 917-13-5 ≥99% 2014-01-13 111.867894413750 enniatin-b Antibiotic 86/88 528-​09-​6 11029-​11-​1 natural products inhibitors ions channels apoptosis cancers enniatins cyclihexadepsipeptides Pdr5p yeast inhibits inhibitions fungi pleiotropic drugs reistances proteins 5 five caspases cells channels blockers acyl-CoA cholesterol acyltransferase cholesteryl ester formations caspases ACAT 111.867894413750
10112 (±)-Enterolactone 78473-71-9 ≥95% 25.386163290362 -enterolactone HPMF lignans plants antioxidants cancer oxidative injury stress enterobacterial 25.386163290362
500520 Enterolactone EIA Kit - 2005-03-15 122.793443830570 enterolactone-eia-kit Enterolactone ELISA Kit solid plates steroids measures kits eias enzyme immunoassays ELISAs endocrinology assays enterolactones mammalian lignans phytoestrogens estrogen-like diphenols diphenolics intestinal intestines bacterias plant matairesinol secoisolariciresinol diets dietary acute coronary hormone-dependent cancers osteoporosis serums plasmas fiber 122.793443830570
11601 Enzastaurin New 170364-57-5 ≥98% 2013-11-01 79.804899295507 enzastaurin LY317615 Inhibitors inhibits inhibitions proteins kinases signals transductions cancers apoptosis angiogenesis potent PKs PKCs PKCβ PKCb PKCbeta PKC.beta. PKC-β PKC-b PKC-beta PKC-.beta. β b beta .beta. Akts proliferation tumor cells antineoplastic anti neoplastic anti-neoplastic Lys LY-317615 317615 79.804899295507
10477 EP2 Receptor Polyclonal PE Antibody - 2010-07-07 23.515432780847 ep2-receptor-polyclonal-pe-antibody PGE2 Receptor 2; Prostaglandin E2 Receptor 2 R-phycoerythrin immunofluorescent FL-2 FL2 FL 2 channels G-protein coupled G protein flow cytometry FC immunofluorescence IF EP1 EP2 EP3 EP4 cAMP smooth muscles mRNA tissues lungs placenta placenta spleen intestines kidneys sensory neurons 23.515432780847
600410 EP4 Receptor (rat) STEP Plate Assay Kit (cAMP method) - 2011-06-28 7.704834254143 ep4-receptor-rat-step-plate-assay-kit-camp-method cell-based assays cells CBAs kits measures measurements prostaglandins E2 PGE2 prostanoids G protein-coupled receptors proteins GPCRs EP1 EP2 EP3 signals transductions mechanisms tissues localizations regulation expression intestines lungs kidneys thymus uterus brains cyclics AMP adenosines monophosphates pathways phosphatidylinositols 3-kinases G1 smooth muscles relaxation gastric secretions intestinal epithelial transportation adrenal aldosterone uterine immunity inflammation human colon cancers colorectal carcinogenesis in vivo neuroprotective excitotoxic injury injuries agonists antagonists therapeutics diseases surface transfections and expression protocols transient technology technologies University of Michigan UM U of M Originus, Inc. USPT United States patents 6897067 6902933 7056741 DNA deoxyribonucleic recombinant proteins cells receptor-mediated endocytosis solution-phase efficiency multiple plasmids constructs intracellular 7.704834254143
11807 (−)-Epicatechin 490-46-0 ≥90% 2013-07-01 9.440324210886 -epicatechin epi-Catechin; NSC 81161 2545-08-6 863644-80-8 863644-83-1 antioxidants flavonoids oxidatives injury injuries cancers natural products epicatechins catechins anti-oxidants oxidants anti COXs COX-1 COX1 cyclooxygenase-1 cyclooxygenases 1 cyclooxygenase1 apoptosis induces inducers adenocarcinomas PC-9 PC9 PCs 9 cells inhibitions inhibitors inhibits TNFs tumors necrosis factors factor-.alpha. factor-a factor-alpha factor-α α TNF-.alpha. TNF-a TNF-alpha TNF-α alpha .alpha. a stereoisomer isomers BALBc BALB-c BALBs c 3T3 epigallocatechin gallate en tent-catechin NSCs 81161 NSC81161 NSC-81161 L-epicatechin epicatechol I-acacatechin I-epicatechin I-epicatechol 2R,3R 2R/3R 2R3R 2R 3R tea leaves leaf grapes seeds woods barks trees acacia mahogany ascorbate α-tocopherols alpha-tocopherols .alpha.-tocopherols a-tocopherols tocopherols in vitro lipids peroxidations assays stereoisomers BALB-c/3T3 9.440324210886
11808 (−)-Epicatechin Gallate 1257-08-5 ≥98% 2013-06-13 7.824113849400 -epicatechin-gallate ECG Naturals products cancers antioxidants inflammations polyphenols protectives actions diverses catechins epicatechins EC epigallocatechins gallates EGCG greens blacks teas ECG inhibits inhibitors inhibitions cells anti-inflammatory antiinflammatory anti inflammatory methicillins resistant strains S. aureus S.aureus 3-O-gallate O-galloylepicatechin L-ECG singles galloyl groups growth effects hydroxyls potent facilitates killings 7.824113849400
11809 (−)-Epigallocatechin New 970-74-1 ≥98% 2014-04-11 0E-12 -epigallocatechin EGC; NSC 674039; epi-Gallocatechin 2545-09-7 98032-84-9 green teas polyphenols catechins antioxidants anti oxidants anti-oxidants antiinflammatory cancers anti-cancers anti-inflammatory anticancers free radicals scavengers natural products epigallocatechin DPPH radicals inhibits inhibitions inhibitors heregulin-β1 heregulin-b1 heregulin-beta1 heregulin-.beta.1 MCF-7 MCFs 7 seven MCF7 breast cells epi gallocatechin antiscurvy factors C2 galloepicatechin NSCs 674039 NSC-674039 NSC674039 sunphenon anti inflammatory aml (-)-Epigallocatechol Epigallocatechol (-)-epi-Gallocatechin LEpigallocatechin NSC674039 NSC-674039 epi-Gallocatechin l-Epigallocatechin l l-Epigallocatechol Epigallocatechol 0E-12
12091 Epirubicin (hydrochloride) 56390-09-1 ≥98% 2013-08-14 16.339286343762 epirubicin-hydrochloride 4’-Epidoxorubicin 56420-45-2 4-epidoxorubicin antitumors anti-tumors tumors anti anthracycline doxorubicin β-glucuronidation cytotoxic .beta.-glucuronidation beta-glucuronidation b-glucuronidation glucuronidation b beta .beta. cytotoxic HeLa cells therapies remissions cancers ovary ovarian lymphomas breasts pancreas gastric hepatocellular carcinomas heads necks colorectal epidoxorubicin 4s fours HCls Ellence farmorubicin pharmorubicin antibiotics inhibitors inhibits inhibitions epirubicin stereoisomers detoxifies dose-limiting doses limiting sides effects 16.339286343762
10924 Epothilone B 152044-54-7 ≥95% 2011-07-27 18.793839779005 epothilone-b macrolides inhibitors inhibits inhibition tubulin microtubules polymerization cancers cells cycle mitotic arrest mitosis Hs578T HeLa KB3-1 KB31 KBV-1 KBV1 cytoskeletal 18.793839779005
10007806 Epoxomicin 134381-21-8 ≥98% 2008-12-09 22.765502762431 epoxomicin BU 4061T inhibitors inhibits inhibition proteins degradation 20S proteasomes antitumors bones formation Parkinsons diseases anti-tumors 22.765502762431
13184 (±)-Equol 94105-90-5 ≥98% 2009-09-03 7.916132596684 -equol phytoestrogens estrogens daidzen genistein receptors cancers nonsteroidal ERα ERβ ERalpha ER.alpha. ERbeta ER.beta. breast cells proliferation 7,4'-homoisoflavone NV 07α 07alpha 66036-38-2 7.916132596684
10010238 Erbstatin Analog 63177-57-1 ≥98% 2008-06-06 31.225050000989 erbstatin-analog Methyl 2,5-dihydoxycinnamate analogs EGF EGFR inhibitors inhibits inhibition tyrosine kinase DNA synthesis cell cycle proliferation cancers 31.225050000989
10483 Erlotinib 183321-74-6 ≥98% 2010-08-11 43.052017816112 erlotinib NSC 718781; CP 358,774 tyrosine kinase inhibitor inhibits inhibiting epidermal growth factor receptors EGFR cancers tumor cyclin-dependent cyclin dependent kinase 2 Cdk-2 Cdk 2 Cdk2 JAK-2 JAK2 JAK JAK2V617F CP-358,774 CP-358774 CP 358774 CP358774 CP358,774 NSC-718781 NSC718781 OSI-744 OSI744 R-1415 R1415 R 1415 OSI 744 Quinazolines CDKs 43.052017816112
14017 Erucin 4430-36-8 ≥98% 2012-11-29 4.380005586939 erucin isothiocyanate glucoerucin glucosinolate sulforaphane antiapoptotic antioxidant cells cycles regulation cancers neuroprotective effects arugula Eruca sativa Mill veggies vegetables induces growth inhibition apoptosis induction detoxification enzymes prostates lungs livers colon 4.380005586939
12092 Etoposide 33419-42-0 ≥98% 2012-10-15 9.338062154382 etoposide Lastet; Fytosid; VP-16-123; Celltop; EPE; NSC 141540; Zuyeyidal 35317-32-9 51854-34-3 76576-58-4 121471-01-0 136598-18-0 201594-04-9 epipodophyllotoxin VP 16213 eto-gry etosid eposin NSC141540 NSC-141540 toposar VP16 VP-16 VP 16 pharmaceutical VP 16-123 VP16-123 VP-16-123 VP 16-213 VP16-213 VePesid vepesid J trans-etoposide inhibitors cancers cells cycles steroids estrogen receptors mitosis histones acetyltransferase epigenetics plants alkaloids inhibits inhibitions cytotoxicity assays DNA synthesis ternary complex topoisomerase II multidrug multi-drug 9.338062154382
10006329 EUK 134 81065-76-1 ≥98% 2005-03-02 43.826104972375 euk-134 salen manganese SOD ROS catalse stroke oxidative injury porphyrin scavengers peroxynitrites superoxides hydrogen peroxides arteries artery cerebral H2O2 infarct volumes EUK 134 EUK-134 EUK134 43.826104972375
11597 Everolimus New 159351-69-6 ≥98% 2014-01-13 142.249772866790 everolimus RAD001; Certican; NVP-RAD001; Afinitor® inhibitors cancers intracellular signaling signals transduction kinases rapamycin derivatives mammalian targets mTORs mTORC1 mTORC2 complexes mTORCs hydroxyethyl ether inhibits inhibitions pharmacokinetics pharmacodynamics cells proliferation metabolism angiogenesis immunosuppressive agents organ transplants transplantation SDZ-RAD xience v afinitor certican 1245613-55-1 zortress 142.249772866790
15008 Exemestane 107868-30-4 95% 2013-04-23 1.159791178949 exemestane FCE 24304; Aromasin™ steroids endocrinology inhibitors cancers aromasin aromatases breasts estrogens third 3rd generations steroidal inhibits inhibitions induces degradations decreases plasma lower HDL cholesterols apo A1 apo-A1 apoA1 triglycerides postmenopausal post-menopausal posts menopausal aromasil FCE24304 FCE 24304 FCE-24304 irreversible levels androgens analogs androgenics effects high-density high density lipoproteins total receptor-positive receptors positives 1.159791178949
13487 EZH1 Polyclonal Antibody - 2009-07-14 0E-12 ezh1-polyclonal-antibody Western blots WB immunoblotting blotting 0E-12
10022 F16 36098-33-6 ≥98% 7.276906077348 f16 apoptosis induces apoptotic mitochodrial membranes tumors inhibitors fluorescent F-16 cancer inhibits fluorescence lipophilic binding HER-1/EGFR-expressing inhibition cells breast 7.276906077348
10010019 FABP2 Polyclonal Antibody - 2007-10-02 5.898780584056 fabp2-polyclonal-antibody I-FABP; Fatty Acid Binding Protein 2; Intestinal-Fatty Acid Binding Protein WB western blots fatty acids FABPs lipophilic ligands metabolism polymorphism FABP2 IFABP obesity diabetes antibodies antiserum diabetic antisera atherosclerosis endocrinology blotting immunoblotting 5.898780584056
10010364 FABP5 (human recombinant) - ≥95% 2007-08-08 15.672710635358 fabp5-human-recombinant DA11 FABP; E-FABP; Epidermal-FABP; Fatty Acid Binding Protein 5; Psoriasis-Associated FABP; Keratinocyte FABP proteins lipophilic ligands uptake metabolism cellular membranes FABP-5 FABPs cytosolic fatty acids bladders carcinoma prostates atherosclerosis endocrinology 15.672710635358
10009551 FABP7 (human recombinant) - ≥90% 2007-06-27 6.929786898184 fabp7-human-recombinant Fatty Acid Binding Protein 7; Brain-FABP; B-FABP cytosolic FABPs amino acids lipophilic ligands tissues metabolism pathways docosahexanoic fatty binding proteins atherosclerosis endocrinology 6.929786898184
14485 FAK Inhibitor 14 4506-66-5 ≥95% 2013-06-12 5.404972375691 fak-inhibitor-14 Focal Adhesion Kinase; Y15 3204-61-3 inhibitors kinases cancers vascular diseases FAKs focal adhesion kinases inhibits inhibitions autophosphorylation blocking blocks Y397 Y-397 Ys 397 Y-15 Y15 15 promotes cells detachment cultures tumors growths in vivo regulations aortic stiffness receptors tyrosine regulates spreading migration proliferation apoptosis over expressed over-expressed direct phosphorylation 5.404972375691
10610 F-Amidine (trifluoroacetate salt) 877617-46-4 ≥95% 2011-09-23 19.449530386740 f-amidine-trifluoroacetate-salt proteins arginine deiminase 4 PAD4 cancers arthritis inhibitors histones genes expression cysteine PAD1 PAD3 cytotoxic HL-60 MCF7 HT-29 877617-46-4 PADs PAD-1 PAD-3 PAD-4 peptidyl arginine 19.449530386740
10010501 Farnesyl Thiosalicylic Acid 162520-00-5 ≥96% 2008-06-02 9.413870634228 farnesyl-thiosalicylic-acid FTS; Salirasib ras inhibitors inhibition inhibits cancer anti-cancer anticancer prenylation farnesylation signal transduction oncogene atherosclerosis farnesylthiosalicylic acid 9.413870634228
13175 Farnesyl Thiosalicylic Acid Amide Exclusive 1092521-74-8 ≥96% 2009-02-26 4.929875690608 farnesyl-thiosalicylic-acid-amide FTS Amide; Salirasib Amide Ras degradation cells signaling signalling tumors glioblastoma cancers inhibitors inhibits inhibition 4.929875690608
13562 Fatostatin (hydrobromide) 298197-04-3 ≥95% 2013-09-19 10.426212110226 fatostatin-hydrobromide 125B11 125256-00-0 inhibitors metabolism diabetes obesity cancers intracellular signaling transcription factors signals transduction inhibits sterols regulatory elements binding proteins SREBPs lipogenesis fats cleavage-activating cleavage activating SCAP SREBP-1 SREBP 1 one SREBP-one SREBP-2 SREBP 2 two SREBP-two adipogenesis insulin-induced insulin induced insulin-like like growth factor 1 one IGF1 IGFone IGF lipids A 10.426212110226
11960 FC 131 606968-52-9 ≥95% 2012-12-10 1.357651933701 fc-131 inhibitors cancers chemokines CXCL12 SDF-1 hematopoiesis arthritis HIV viral infection receptors antagonists inhibits inhibitions SDF1 SDF FC131 FC-131 C-X-C stromal cells derived cell-derived CXC4 CXC-4 CXCs CXCL-12 CXCL motif 1.357651933701
11880 Ferulic Acid ethyl ester 4046-02-0 ≥98% 2012-07-25 3.249217898984 ferulic-acid-ethyl-ester BBR 3222; NSC 14879 BBR3222 BBR-3222 ethyl ferulate NSC14879 NSC-14879 antioxidants neuroprotective cytoprotective inflammation cancers FAEE ferula communis F. communis fennel plants lipophilic derivatives cross cells membranes increases expressions heme oxygenase-1 oxygenase HSP70 HSP-70 HSP 70 HSP-72 HSP72 HSP 72 neuroprotection peptides 3.249217898984
14938 Finasteride 98319-26-7 ≥95% 2013-09-18 17.168071268460 finasteride MK 906; Propecia®; Proscar® MK-906 5α-reductase steroids metabolisms testosterone dihydrotestosterone DHT prostate cancers type I type II 4-azasteroid analogs inhibitors benign prostatic hyperplasia androgenic alopecia inhibits inhibitions NADPH Δ4,5 substrates growth skin liver ventral epididymis reproductive tissues blocks enzymes Nrf2 HO-1 proteins PC-3 cells tumors procollagen TGF-β1 expressions humans scalps dermal fibroblasts chibro-proscar chibro finara finest finastid finax fincar finpecia fistide MK906 prosteride prostide 17.168071268460
13287 FK-866 658084-64-1 ≥98% 2009-07-21 37.109686924493 fk-866 K 22.175 nicotinamides phosphoribosyltransferase NAMPT NamPRT PBEF visfatin mononucleotides adenine dinucleotide NAD+ inhibitors inhibitis inhibition cancers apoptosis SIRT1 autophagy FK866 FK 866 K22.175 K 22175 K22175 NamPRT PBEF visfatin carcinoma cells autophagy 37.109686924493
10009197 Flavopiridol 146426-40-6 ≥95% 2013-06-17 31.692681092695 flavopiridol L-868,275; HL 275; Alvocidib; HMR 1275 358739-39-6 inhibitors inhibits inhibitions kinases cancers arthritis cyclin-dependent CDKs positive transcriptions elongation factors P-TEFb PTEFb P TEFb potent Cdk9 Cdk-9 9 nine prevents prevention HIV-1 HIV1 HIV 1 one humans immunodeficiency virus isoforms epidermal growths factors receptors EGFRs proteins A PKA therapy joints synovial hyperplasia destruction collagen HMR-1275 HMR1275 HMR 1275 L86-8275 L868275 L8 8275 HL 275 HL-275 HL275 RNA subunits polymerases II 31.692681092695
14154 Floxuridine 50-91-9 ≥98% 2013-04-01 33.039411764706 floxuridine 5-FDU; NSC 26740; 5-Fluorodeoxyuridine; NSC 27640 888-03-9 3460-74-0 deoxyfluorouridine 5-fluorouracil deoxyribosides FdUrd 5-FUdR floxuridin NSC27640 NSC-27640 NSC26740 NSC-26740 Inhibitors cancers inhibits inhibitions prodrugs pro-drugs DNA metastases livers synthesis deoxyribonucleic acids in vivo catabolized catabolyzes injections thymidylate synthases synthesis 33.039411764706
14128 Fludarabine 21679-14-1 ≥98% 2013-04-11 3.748196456124 fludarabine F-ara-A; NSC 118218 nucleotides apoptosis NSCs 312878 antitumors DNA deoxyribonucleic acids synthesis inhibitors nucleosides analogs leukemia anticancers NSC-312878 NSC312878 inhibits inhibitions anti-cancers anti cancers adenosines deaminases reistant 9-β-D-arabinofuranosyladenine 9-b-D-arabinofuranosyladenine 9-.beta.-D-arabinofuranosyladenine 9-beta-D-arabinofuranosyladenine tumors systems LI210 leukemias CD8F mammary adenocarcinomas P388 LX-1 lungs xenograft hematological malignancies NSC-118218 NSC118218 NSC 118218H antiproliferatives cells lines blood Bax Bid XIAP survivin expressions in vivo purines 3.748196456124
14416 Fluorouracil 51-21-8 ≥95% 2013-05-23 7.966961325967 fluorouracil NSC 19893; U-8953; Ro 2-9757 1004-03-1 4921-97-5 79108-01-3 cancers inhibitors inhibits inhibitions pyrimadines analogs thymidylate blocks blocking synthases deoxyribonucleic acids DNA synthesis cells deaths apoptosis cancers intracellular cytotoxicity cytotoxins metabolites RNA gastrointestinal tracts adenocarcinomas drugs resistances adrucil arumel carac carzonal DBL efudex efudix efurix FU fluoroblastin fluoroplex flurablastin fluracedyl fluracil fluracilum fluri fluril ftoruracil kecimeton nsc-19893 NSCs 19893 NSC19893 phthoruracil phoruracil queroplex Ro 2-9757 Ro-2-9757 Ros 29757 Ro-29757 Ro2-9757 Ro29757 Ro2 9757 timazin U8953 U-8953 Us 8953 Ulup 7.966961325967
14749 Fostriecin 87810-56-8 ≥95% 2013-09-12 10.900966632550 fostriecin Phosphotrienin; Antibiotic CI-920; NSC 339638 87860-39-7 96612-73-6 inhibitors phosphatases histones modifications epigenetics cancers PP2A PP4 proteins serine/threonine serine threonine H3 phosphorylation phosphorylates regulations cells proliferation proliferates antitumors anti-tumors anti tumors antibiotics CL 1565A sodium salts 10.900966632550
14709 FSLLRY-amide 245329-02-6 ≥95% 2013-07-22 20.182872928177 fsllry-amide inhibitors antivirals anti virals anti-virals analogs guanosine inhibits inhibitions inhibiting reverse transcriptase immunodeficiency virus type 1 one therapy retroviral hypersensitivity syndromes trypsin SLIGRL-NH2 SLIGRLNH2 SLIGRL NH2 thrombin PAR1 PAR-1 1 activation proteolysis casein 20.182872928177
10011269 Fulvestrant 129453-61-8 ≥98% 2009-02-24 46.705386740331 fulvestrant Faslodex®; ICI 182,780 estrogen receptors ER ERα agonist antagonist activator breast cancers hippocampus neurons ICI182780 ZD182780 ZD9238 ZM182780 46.705386740331
11332 Fumagillin 23110-15-8 ≥95% 2012-02-22 10.488397790055 fumagillin Amebacilin; NSC 9168 297-95-0 47721-00-6 47721-01-7 106215-84-3 746540-00-1 fugillin fumadil B fumagillin fumagillin DCH fumidil microsporidia inhibitors angiogenesis cancers cells growth proliferation genes expression fungus infection infectious diseases adipose tissues obesity Aspergillus fumigatus MetAP2 antibiotics 10.488397790055
11030 Fumitremorgin C 118974-02-0 ≥98% 2012-03-30 78.489871086557 fumitremorgin-c Tryptoquivaline 12α-fumitremorgin C cancers multidrug resistance transporters inhibitors inhibition inhibits efflux toxicity breasts proteins BCRP/ABCG2 mitoxantrone doxorubicin topotecan S1-M1-3.2 colon carcinoma cells ABCB1 MRP1 ABCC1 P-glycoproteins fumitremorgin-C 78.489871086557
14673 G-15 1161002-05-6 ≥95% 2013-07-24 71.486640876005 g-15 receptors antagonist cancers diabetes bones-related research bones related GPER g protein coupled estrogen protein-coupled GPR30 GPR-30 GPRs 30 non-steroidal nonsteroidal non steroidal antagonists estrogens ERs G15 Gs 15 G-15 antidepressive anti depressive anti-depressive in vivo 71.486640876005
14397 G-36 New 1392487-51-2 ≥98% 2013-11-08 52.294073648880 g-36 receptors antagonists steroids endocrinology biochemistry cancers diabetes bone-related research bones related G proteins coupled estrogens GPR30 GPR-30 GPRs 30 GPERs cell-permeable cells permeables non-steroidal nonsteroidal non steroidal 17β-estradiol 17beta-estradiol 17.beta.-estradiol 17b-estradiol estradiol G1 G-1 Gs 1 36 G36 ERs Erα ERβ ERalpha ERbeta ER.alpha. ER.beta. Era ERb ERKs EGFs 52.294073648880
10353 G9a (human recombinant) - ≥70% 2011-03-08 10.840566298342 g9a-human-recombinant KMT1C; Euchromatic Histone-Lysine N-Methyltransferase 2; EHMT2 lysines methylation methyltransferases genes silencing repression proteins recombinants set domain-containing pluripotency H3K9 GLP active 10.840566298342
10755 G9a-like protein (human recombinant) - ≥95% 2011-10-13 10.745292817679 g9a-like-protein-human-recombinant KMT1D; Euchromatic Histone-Lysine N-Methyltransferase 1; GLP; EHMT1; Eu HMTase 1 lysine methylation methyltransferase genes silencing repression SET domain histones modifications GLP H3K9 BIX-01294 UNC0638 inhibitors inhibits inhibition SAR monomethylate dimethylate BIX01294 BIX 01294 UNC-0638 UNC 0638 active 10.745292817679
10008346 Gabapentin 60142-96-3 ≥98% 2006-04-20 27.298674033148 gabapentin Neurontin® antiepileptic drugs Gamma-aminobutyric acids GABA neurotransmitters receptors spinal cord analogs anticonvulsants analgeics neuropathics pain syndromes Complex Regional types CRPS1 multiple sclerosis dysesthesias cancers HIV infections CNS central nervous systems calcium channels .gamma.-aminobutyric g-aminobutyric neurochemistry 27.298674033148
15387 Galiellalactone New 133613-71-5 ≥95% 2014-01-09 92.010978616737 galiellalactone fungal metabolites ascomycetes IL-6 JAK/STAT signals transduction STAT3 prostate cancers inhibitors inhibits inhibitions STAT 3 three G. rufa IL interleukin IL-6 6 six IL6 HepG2 stems cells therapeutic transcription factors cytokines antibiotics ascomycetes 92.010978616737
14761 Gambogic Acid 2752-65-0 ≥95% 2013-08-05 4.048517097704 gambogic-acid GA; β-Guttiferin 18833-83-5 apoptosis cancers anti-cancers anti-tumors antitumors anti tumors anticancer transferrin receptors ions channels inhibitors inhibits inhibitions proteasomes AMPK Akt mTor bcl-2 bcl2 bcl 2 two GA natural products garcinia hanburyi tree G. cellular cells pathways activates caspases binding binds anti-apoptotic antiapoptotic apoptotic proteins BH3 BH-3 peptides Bax 20S dose-dependent doses dependents manners gliomas EGFR Akt/mTORC1 mTORC1 expressions potent slow Kir2.1 Kir-2.1 Kir 2.1 chymotrypsins activity activities signaling signalling trees exhibits exhibiting BH 3 three Bcl-XL BclXL XL Bcl-W BclW W Bcl-B BclB B Bfl-1 Bfl1 Bfl 1 one Mcl-1 Mcl1 Mcl lines AMPK-initiated initiated effects deaths 4.048517097704
15585 Ganglioside GD1a (sodium salt) New 12707-58-3 ≥98% 2014-03-05 0E-12 ganglioside-gd1a-sodium-salt Ganglioside B1; Ganglioside G3 lipids ceramides gangliosides glycosphingolipids sialic acids oligosaccharides microdomains rafts angiogenesis cells signaling tumors proliferation TLR2 innate immunity coreceptors co-receptors co acid-containing sodium salts galatose brain erythrocytes bones marrows testis spleens livers GII angiogeneis 54952-11-3 55598-65-7 59247-12-0 71537-59-2 82497-00-5 0E-12
15588 Ganglioside GT1b (sodium salt) New 59247-13-1 ≥98% 2014-03-06 0E-12 ganglioside-gt1b-sodium-salt Ganglioside G1 60362-​39-​2 62463-​01-​8 lipids ceramides gangliosides glycosphingolipids sialic acids oligosaccharides microdomains rafts trisialogangliosides immune responses infections cells carcinoma immunoglobin IgG IgM IgA polyomavirus cancers merkel inhibits inhibitors inhibitions inhibitory humoral G M A immunology signals transduction 0E-12
14193 GANT 58 64048-12-0 ≥98% 2013-04-25 40.642679558011 gant-58 NSC 75503 2,3,4,5-Tetra(4-pyridyl)thiophene 94345-01-4 genes regulations cancers Gli hedgehog HH signalling signaling signals inhbitors inhibits inhibitions transcriptions NSC75503 NSC-75503 NSCs 75503 Ewing sarcoma family of tumors ESFTs GANT-58 GANTs 58 antagonists Gli-1 Gli1 cells smoothened Smo endogenous Sufu proteins development Patched vertebrates zinc-finger factors pathways cancers glioblastomas Gli1-mediated downstream nuclear antiproliferatives anti-proliferatives antitumor anti-tumor 40.642679558011
13841 GANT 61 500579-04-4 ≥98% 2011-04-20 107.916436464088 gant-61 NSC 136476 Hedgehog transcription factors genes expression Gli cancer glioblastomas antagonists development regulations GANT61 GANT-61 pyridines pyrimidines NSC136476 NSC-136476 TFs 107.916436464088
10566 Garcinol 78824-30-3 ≥95% 2011-10-25 10.414799723756 garcinol Camboginol inhibits inhibitors inhibition histones acetyltransferases HATs p300 PCAF GCN5 neurogenesis stem cells apoptosis cancers antiinflammatory anti-inflammatory inflammation neuroscience genes expressions regulations epigenetics 10.414799723756
10782 Gcn5 (human recombinant) - ≥80% 2011-12-05 9.364651933701 gcn5-human-recombinant STAF97; KAT2A; General control of amino acid synthesis protein 5-like 2; Lysine acetyltransferase 2A epigenetics modifications histones acetylation cancers GNAT N-acetyltransferases enzymes STAGA TFTC SAGA ATAC H3K14 H3K9 H3K18 H4K8 H4K16 H3 H2B KAT2B p300/CBP associated factors Spt-Ada-GCN5-aceytltransferase Ada Two-A containing CoASH Gcn-5 N-acetyltransferases enzymatic subunits complexes proteins active 9.364651933701
13613 GDC 0449 879085-55-9 ≥98% 2013-10-22 6.761229314421 gdc-0449 Vismodegib receptors antagonists cancers inhibitors signals transductions inhibits inhibitions potent antagonist smoothened SMO GDCs 0449 GDC-0449 GDC0449 bisphasic manners tumors ATPs bindings ATP-binding cassette ABCs proteins ABCG2 ABCB1 drugs reistance basal cells carcinoma 6.761229314421
11600 GDC 0941 New 957054-30-7 ≥98% 2013-12-03 82.760090546347 gdc-0941 Pictrelisib; Pictilisib; GNE 0941 1146702-​55-​7 inhibitors signals transductions cancers kinases GDCs 0941 GDC0941 GDC-0341 pan inhibits inhibitions class I PI3K isoforms phosphatidylinositol-3-kinase phosphatidylinositol 2 three catalytic subunits p110 cells blocks blockage signaling Akt in vivo GNEs GNE-0941 GNE0941 pictilisib pictrelisib 82.760090546347
13166 Gefitinib 184475-35-2 ≥98% 2010-02-11 33.696210420007 gefitinib ZD1839; Iressa™ EGFR-TK EGFRs TKs epidermal growth factors inhibitors cancers signal transduction tyrosine kinases inhibits inhibited NSCLC Quinazolinones 33.696210420007
13355 Geldanamycin 30562-34-6 ≥98% 2010-07-29 12.101356660528 geldanamycin NSC 122750 NSC 212518 antibiotics heat shock proteins 90 Hsp90 GRP94 gp96 genes expression cells proliferation apoptosis angiogenesis c-jun adenocarcinoma cancers AP-1 steroids receptors 2,5-Cyclohexadiene-1,4-Diones 1,4-Benzoquinones 1,2-Benzoquinones p-Benzoquinones-o-Benzoquinones Benzoquinones Benzodiones Quinones geldanomycin GDM NSC122750 NSC-122750 NSC 122750 AC-6794 BRN 1633093 geldanamicin 30562-34-6 antibiotic U29135 U-29135 U 29135 AC1NQZ81 ligands GRP94 Hsp 90 12.101356660528
11690 Gemcitabine 95058-81-4 ≥98% 2012-05-23 13.521823204420 gemcitabine DDFC; Gemzar; LY 188011; Folfugem; GemLip; Zefei; Gemcel; NSC 613327 nucleosides analogs anticancer non-small cells lungs pancreatic bladder breasts cancers anti-tumor tumors replication repair Gadd45a DNA demethylation antiretroviral AIDS 1239668-67-7 DFdC DFdCyd gamcitabine LY-188011 NSC613327 NSC-613327 LY188011 Gadd45a murine rat mouse 13.521823204420
10005167 Genistein 446-72-0 ≥98% 2004-08-04 9.028768912995 genistein isoflavonoids phytoestrogenics legumes glycosides carcinogenic tumors inhibits inhibition inhibitors estrogenic isoflavones uterine DES diethylstilbestrol histones H2B endocrine tyrosine chemopreventitive 9.028768912995
14174 Genistin 529-59-9 ≥98% 2013-04-23 9.811256906076 genistin NSC 5112 natural products flavonoids cancers bones related research bone-related isoflavones legumes soy kudzu phytoestrogens estrogens dependent breast cells proliferations marrow stromal osteoblasts suppresses suppression turnover formations forms collagen matrix genistine genistoside genisteol 7-monoglucoside NSCs 5112 NSC5112 NSC-5112 25449-68-7 30370-89-9 100455-46-7 humans in vivo 9.811256906076
63330 Geranylgeranyl Pyrophosphate (ammonium salt) New 313263-08-0 ≥95% 2013-10-30 13.591519122875 geranylgeranyl-pyrophosphate-ammonium-salt GGPP 6699-20-3 isoprenoid intermediates HMG-CoA HMG CoA HMGCoA reductase pathways biosynthesis isoprenylation GTPase farnesyl pyrophosphate FPP GGPP post-translational modification anticancers posts translational anti-cancers anti cancers drugs discovery 13.591519122875
14190 Gilvocarcin V 77879-90-4 ≥98% 2013-02-13 1.503922651933 gilvocarcin-v DC-38-V; NSC 338943; Antibiotic 1072B; NSC 348115; Toromycin A; Anandimycin A 84236-01-1 natural histones modifications infectious diseases inhibitors inhibits inhibitions cancers antitumors antibiotics DNA synthesis cross-linking histones H3 GRP78 GRP-78 GRPs 78 gilvocarcin-V Streptomyces S. gilvotanareus aureus staphylococcus bacillus subtilis b. bacterias sarcoma 180 Ehrlich carcinomas Meth I fibrosarcoma MH134 hepatomas leukemia P388 P-88 inhibits inhibitions cross links linking heat shock UV light NSC348115 NSC-348115 NSC338943 NSC-338943 1.503922651933
14636 Ginkgolide B 15291-77-7 ≥98% 2013-06-24 6.294198895028 ginkgolide-b BN 52021; BN 52051 99796-69-7 BN 52021 BN52021 BN-52021 52051 BN52051 BN-52051 platelets-activating platelets activating actives activates factors receptors PAFs aggregations PAFR antagonists anticancer anti-cancer anti cancers inflammatory antiinflammatory allergic anti-allergic oxidants anti-oxidant anti-inflammatory anti-allergic antioxidants neuroprotectives ginkgolide-b terpenoids ginkgo biloba g. leaves ovarian mucinous bilobalide mediators cells proliferations angiogenesis responses regulations vasodilations superoxides formations G-protein Gs proteins coupled receptors tranduces signals phosphorylations cascades ginkgolide Bs inhibits inhibiting inhibitions inhibitors extracted cancers blocking cycling 6.294198895028
15330 Ginsenoside Re New 52286-59-6 ≥98% 2014-01-20 187.037037037037 ginsenoside-re Chikusetsusaponin IVc; Panaxoside Re; Sanchinoside Re; NSC 308877 75139-​46-​7 212055-​74-​8 324018-​82-​8 natural products hypertension inhibitors oxidative injury diabetes angiogenesis cancers inhibits inhibitions ginsenosides panax genus panaxatriol saponin P. quinquefolium in vitor vivo vasorelaxants antioxidants antihyperlipidemic anti hyperlipidemic anti-hyperlipodemic angiogenic anti-oxidant oxidants chemotherapeutics agents steaming heating plants steroids diverse effects B2 NSCs 308877 NSC308877 NSC-30877 glycosides squalene multidrug resistance proteins 1 ones P-glycoprotein B2 187.037037037037
15332 Ginsenoside Rg3 New 14197-60-5 ≥95% 2014-01-13 144.666666666666 ginsenoside-rg3 11019-​45-​7 12770-​19-​3 47891-​53-​2 195711-​65-​0 natural products neurosciences inflammation hypertensions apoptosis angiogenesis ginsenosides ginseng plants panax steroids triterpene squalene Rg3 panaxadiol P. in vitro in vivo anti-cancers cancers anticancers neuroprotective anti-hypertensive hypertensive antihypertensive anti-inflammatory inflammatory antiinflammatory glycosides 20S-ginsendoside 144.666666666666
10009445 Glucoraphanin 21414-41-5 ≥95% 2013-07-30 13.794766446190 glucoraphanin naturals products cancers inflammations antioxidants protectives effects glycoinsolate cruciferous vegetables broccoli isothiocyanate sulforaphane myrosinase sulforaphane anti oxidants anti-oxidant anti-inflammatory antiinflammatory inflammatory carcinogenic anti-carcinogenic anticarcinogenic nuclears factors erythroid 2 related two Nrf2 Nrf-2 Nrfs 2 detoxification enzymes sulforaphane flucosinolate flucorafanin methylsulfinylbutyl 457655-34-4 1245747-40-3 glucoraphanin phase II 13.794766446190
15239 Glucoraphanin (potassium salt) New - ≥95% 2013-11-11 34.199856813483 glucoraphanin-potassium-salt 21414-41-5 1453081-26-9 natural products cancer cardiovascular diseases cytochromes P450 CYP450 precursor sulforaphane 10496 crucifers broccoli cauliflower metabolized in vivo cancers protective phase II enzymes lipids amino acids metabolism I carcinogen-activating carcinogen activating lungs potassium salts vascular 10009445 glucoraphanin glucosinolate inducer cancer-protective ingestion risks humans biomarkers expression P 450 isoforms rats 34.199856813483
700300 Glucose-6-Phosphate Dehydrogenase Activity Assay Kit - 2011-07-28 87.196109735187 glucose-6-phosphate-dehydrogenase-activity-assay-kit G6PDH kits assays measures measurements Glucose 6 six phosphates Glucose-6-phosphates dehydrogenases cytosolic enzymes catalyzes pentose pathway ribose-5-phosphates precursor RNA ribonucleic acids DNA deoxyribonucleic ATP adenosine triphosphates CoA coenzymes A NAD nicotinamides adenine dinucleotides FAD flavin NADPH phosphates energy cells fatty oxidations lipids biosynthesis substrates oxidases macrophages polymorphonuclear leukocytes oxygen radicals pathogens intracellular metabolic de novo amino red blood RBC mitochondria pentose oxidative damage stress hemolytic anemia neonatal hyperbilirubinemia acute hemolysis chronic X-linked sex-linked hereditary genetics defect mutations G6PD genes malaria Plasmodium falciparum upregulated rat mouse murine obesity hyperglycemia hyperinsulinemia mediator insulin resistance post-translationally preneoplastic lesions tumors suppressors p53 human dimers fluorescence-based erythrocytes lysates tissues homogenates cultures samples 6-phospho-D-gluconate fluorometrics fluorescent 87.196109735187
700750 Glucose-6-Phosphate Fluorometric Assay Kit - 2012-05-25 56.526039779005 glucose-6-phosphate-fluorometric-assay-kit G6P; Robison ester; D-glucose-6-phosphate assays kits measures measurements cells C6H12O6 hexokinases glucokinases intracellular glycolysis phosphoglucose isomerases cellular energy carbons skeletons biosynthesis glucose-1-phosphates phosphoglucomutases glycogen metabolized dehydrogenases G6PDH NADPH Nicotinamides adenines dinucleotides phosphates hexoses monophosphates reducing nucleic acids precursors de novo pathways amino acids pentoses oxidative damages glutathiones reductases GSH deficiency red blood RBCs stress hemolytic anemias livers enzymes glucose-6-phosphatases storage diseases Type 1 I von Gierke's inherited Ia Ib fasting tolerances hypoglycemias growth retardation hepatomegaly accumulation fats fluorescence-based tissues homogenates culture samples 6-phospho-D-gluconate reduction NADP+ detectors fluorescent 56.526039779005
600450 Glycolysis Cell-Based Assay Kit Exclusive - 2011-08-18 102.473010888178 glycolysis-cell-based-assay-kit CBAs assays kits measures colorimetric colorimetric-based L-lactate culture media mediums cellular metabolic pathways glucose metabolisms cells ATP adenosines triphosphates oxygen exercise erythrocytes mitochondria glucoeogenesis intracellular molecules amino acids insulin glycolytic neurons aerobic energy muscles anaerobic cancers lactate pyruvate tricarboxylic acids cycles oxidizes carbon dioxide CO2 water H2O tumor aggressiveness embryonic stem activity hypoxia-inducible transcriptional factors HIF-1 extracellular inhibition inhibits inhibitors chemotherapeutic strategies strategy metabolomic drugs discovery anticancer 102.473010888178
10948 GN25 1227401-27-5 ≥98% 2011-11-30 43.062007366482 gn25 tumors suppressors p53 cancers K-Ras Snail inhibitors mutations exocytosis cells proliferatiion analogs MKN-45 MKN45 MKN 45 A549 HCT116 GN-25 GN 25 genes humans 2-thio-dimethoxy naphthoquinone binding tumors 43.062007366482
10008886 (+)-Goniothalesdiol Exclusive 204975-45-1 ≥98% 2009-03-02 0E-12 -goniothalesdiol antitumor gonoiothalaus borneensis leukemia P338 cells tetrahydrofuran 0E-12
14482 Gossypol 303-45-7 ≥95% 2013-05-28 15.003287906691 gossypol NSC 56817; NSC 624336; BL 193; Pogosin 40112-23-0 732279-01-5 natural products inhibitors inhibits inhibitions cancers infectious diseases infects polyphenols diverse diversity effects racemic mixtures mixes isolated cotton plants genus Gossypium infertility pests spermatogenesis arrests humans antimalarials anti-malarials anti malarials P. falciparum low micromolars aldoses reductases anticancer anti-cancer anti cancers agents cells deaths growths lines blocking blocks anti-apoptotic antiapoptotic apoptotic concentrations Bcl-2 Bcl2 Bcl 2 Bcl-xl Bclxl xl NSCs 56817 624336 NSC-56817 NSC-624336 NSC56817 NSC624336 BL-193 BLs 193 BL193 trash-1 trash 1 trash1 no fertile 15.003287906691
14083 GPR31 (C-Term) Polyclonal Antibody - 2012-12-11 7.397172866789 gpr31-c-term-polyclonal-antibody G Protein-Coupled Receptor 31; 12(S)-HETE Receptor GPR-31 GPR 31 GPRs G protein-coupled receptors G-protein coupled receptors GPCR 12-S-HETE 12(S)-HETE 12S-HETE ERK1/2 ERK 1/2 MAPK3 MAPK1 MEK NF-κB NF-kappa-B NF-.kappa.-B NFκB arthritis Alzheimer's disease prostate cancer 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor 7.397172866789
14033 GPR31 (N-Term) Polyclonal Antibody New - 2013-12-06 59.874717155404 gpr31-n-term-polyclonal-antibody 12(S)-HETE Receptor; G Protein-Coupled Receptor 31 GPRs GPR-31 31 amino acids G protein-coupled proteins coupled receptors GPCRs arachidonic acids metabolites 12(S)-HETE HETEs binding binds binders ERKs ERK-1/2 ERK1/2 MAPK3 MAPK1 MAPKs 3 1 MAPK-3 MAPK-1 MEKs NF-κB NF-kappaB NF-.kappa.B NF-kB diseases arthritis alzheimers prostate cancers signals transductions ELISA flow cytometry FC immunofluorescence IF antibodies N-term Nterms N terms 59.874717155404
10007206 GPR40 Blocking Peptide - 2007-04-12 2.943287292817 gpr40-blocking-peptide immunohistochemistry peptide insulin diabetes breast cancer 2.943287292817
10007205 GPR40 Polyclonal Antibody - 2007-04-04 7.675067526089 gpr40-polyclonal-antibody G Protein-Coupled Receptor 40; FFAR1; Free Fatty Acid Receptor immunohistochemistry antibody insulin diabetes breast cancer endocrinology IHC 7.675067526089
11569 GSK 1059615 958852-01-2 ≥98% 2012-03-15 13.711522682903 gsk-1059615 Phosphatidylinositols PI 3-kinases α PI3Ks PI3Kα PI3Ka PI3K.alpha. inhibits inhibitors inhibition thiazolidinediones cells growth human cancers ATP-competitive p110α p110.alpha. p110a E542K E545K H1047R BT474 tumors xenografts MAPKs signaling biology signals transductions 13.711522682903
15415 GSK 126 New 1346574-57-9 ≥98% 2014-03-04 0E-12 gsk-126 histones H3-lysines H3 H three 3 27 H3K27 methyltransferases EZH2 inhibitors inhibits inhibitions HMTs cancers GSK126 GSK-126 GSKs S-adenosyl-methionine SAM SAMe S-adenosyl methionine S-adenosylmethionine trimethylation trimethylates PRC2 PRCtwo PRCs 2 two genes DLBCL cells xenografts mice mouse chromatin research epigenetics modifications KMT6 0E-12
14094 GSK 343 New 1346704-33-3 ≥98% 2014-01-16 148.685873235113 gsk-343 H3-lysine 27 H3K27 EZH2 inhibitors histones methytranferases HMTs cancers selective GSKs 343 GSK343 GSK-343 inhibits inhibitions HCC1806 cells genes expressions epigenetics chromatin modifications trimethylation 148.685873235113
15219 GSK 3787 New 188591-46-0 ≥95% 2013-12-06 47.829931972789 gsk-3787 PPARs β/δ antagonists cancers lipids homeostasis metabolism pyruvate dehydrogenase kinases 4 PDK4 carnitine palmitoyl transferase 1a CPT1a angiopoietin-like proteins 4 Angptl4 selective irreversible GSKs 3787 GSK3787 GSK-3787 PPARβ/δ PPARb/d PPARbeta/delta PPAR.beta./.delta. PPAR-β/δ PPAR-b/d PPAR-beta/delta PPAR-.beta./.delta. genes PDKs four PDK-4 CPTs 1 a CPT-1a Angptls 4 Angptl-4 47.829931972789
12054 GSK-J1 (sodium salt) - ≥95% 2012-12-06 8.863566605279 gsk-j1-sodium-salt 1373422-53-7 epigenetics demethylase histones JMJD3 cells differentiation developments inflammations cancers GSK-J4 GSKJ4 GSKs GSKJ1 J1 J4 lysine 27 H3K27 H3K-27 inhibitors inhibits inhibitions JMJ JMJD2 JMJD1 kinases prodrugs 8.863566605279
12056 GSK-J2 (sodium salt) Exclusive - ≥90% 2013-03-05 10.245784530386 gsk-j2-sodium-salt 1394854-52-4 epigenetics histones modifications demethylases cancers inhibitors inhibits inhibition inflammation inflammatory GSKJ2 GSKs J2 J5 J4 J1 GSKJ GSKJ1 GSKJ4 GSKJ5 10.245784530386
12073 GSK-J4 (hydrochloride) - ≥95% 2012-12-07 23.002569060773 gsk-j4-hydrochloride 1373423-53-0 epigenetics demethylase histones JMJD3 cells differentiation developments inflammation cancers GSK-J1 pro-drug prodrugs H3 lysine 27 H3K27 H3K-27 GSKJ1 GSKs J1 GSKJ4 J4 inhibitors inhibits inhibitions macrophages reduce LPS induce induced proinflammatory inflammatory pro pro-inflammatory cytokines TNF.alpha. TNF-.alpha. TNF .alpha. TNF-alpha TNF-a TNF-α TNFalpha TNFa TNFα alpha α HCl 23.002569060773
12074 GSK-J5 (hydrochloride) - ≥95% 2013-01-21 11.132348066298 gsk-j5-hydrochloride 1394854-51-3 inhibitors epigenetics histones modification demethylation genes regulation inflammation cancers inhibits inhibitions GSKJ5 GSKs J5 JMJD3 JMJs cells permeable isomers Hcl jumonji domain containing D3 1373423-53-0 11.132348066298
10006611 GW 4064 New 278779-30-9 ≥95% 2014-03-05 0E-12 gw-4064 GW 4064 GW-4064 292047-​56-​4 receptors agonists cancers signals transduction intracellular signaling diabetes obesity obese FXRs farnesoid X GWs 4064 GW4064 GW-4064 selective retinoic acids dyslipidemia diabetes obesity cancers bile nuclear 0E-12
10010368 GW 5074 New 220904-83-6 ≥98% 2013-12-02 42.769392033543 gw-5074 GW-5074 Raf-1 Rafs 1 one Raf1 cRAF c c-RAF kinases proteins kinases cancers signals transductions intracellulars GWs 5074 GW-5074 GW5074 signaling signals potent selective cell-permeable cells permeable inhibitors inhibits inhibitions ERKs ERK1/2 ERK-1/2 ½ epidermal growth factors 42.769392033543
10008313 GW 610 872726-44-8 ≥98% 2006-05-10 32.234668508287 gw-610 NSC 721648 antitumors benzothiazoles inhibits inhibitors inhibition cancers antiproliferative isoflavones quercetin genistein cells MCF-7 MDA 468 NCI 60 32.234668508287
10010556 H-89 127243-85-0 ≥98% 2008-07-08 16.703934371337 h-89 Protein Kinase Inhibitor H-89; 5-Isoquinolinesulfonamide inhibitors inhibits inhibition PKA cAMP cell signaling protein kinase S6K1 MSK1 ROCK-II ROCKII PKB.alpha. PKBalpha PKBa MAPKAP-K1b MAPKAPK1b H89 H 89 16.703934371337
10010249 H-8 (hydrochloride) 113276-94-1 ≥98% 2008-07-17 7.794475138122 h-8-hydrochloride Protein Kinase Inhibitor H-8 PKA PKG PKC MLCK cyclin C Cdk8 cyclin H Cdk7 p36 signal transduction inhibitor inhibits inhibition transcription 84478-11-5 7.794475138122
10010559 HA-1077 (hydrochloride) 203911-27-7 ≥98% 2008-09-03 27.289810536301 ha-1077-hydrochloride protein kinase inhibitors inhibits inhibition ROCK-II ROCKII PRK2 MSK1 MAPKAP-K1b vasodilation hypertension diabetes renal nephropathy cancers 105628-07-7 AT877 AT 877 hydrochloride dihydrochloride monohydrochloride HCl HA1077 HA 1077 Fasudil Eril 27.289810536301
15361 Harringtonine New 26833-85-2 ≥95% 2014-03-27 0E-12 harringtonine NSC 124147 25302-​09-​4 88455-​80-​5 natural products inhibitors cancers inhibits inhibitions alkaloids proteins synthesis homoharrington ribosomes translations NSCs 124147 NSC124147 NSC-124147 harringonin immobilizes initiations homologs chronic myelogenous leukemia ribosome-protected protected mRNA m fragments 0E-12
10006515 HAT Inhibitor Screening Assay Kit - 2006-12-06 9.526384284837 hat-inhibitor-screening-assay-kit Histone Acetyltransferase Inhibitor Screening Assay Kit therapeutics histones p300/CBP-Associated Factors pCAF GNAT GCN5-related N-acetyltransferases acetylates lysines N-terminal terminus tails H3 H4 tumors suppressor genes PTEN human cancers apoptosis fluorescence fluorescent inhibitors fluorometric assays 9.526384284837
10576 HC Toxin 83209-65-8 ≥95% 2010-11-10 19.022969783780 hc-toxin Toxin I (Helminthosporium carbonum) inhibitors histones deacetylases HDACs cancers genes regulation regulates regulators epigenetics HC-toxins cell-permable cells permable 15-lipoxygenase-1 15-LO-1 LOs lipoxygenase 15 1 tetrapeptides peptides helminthosporium carbonums cochliobolus maize pathogens Isomerases Amino Acid Acid Isomerases Amino Racemases Amino Acid Amino Acid Isomerases Acid Racemases Amino Amino Acid Racemases 19.022969783780
13504 HDAC11 Polyclonal Antibody - 2009-07-31 2.422744014733 hdac11-polyclonal-antibody Histone Deacetylase 11 wb western immunoblotting HDACs HAT histones antibodies peptides blots blotting 2.422744014733
10009231 HDAC1 (human recombinant) - 2006-12-06 17.732510359115 hdac1-human-recombinant Histone Deacetylase 1 HDAC 1 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus GST-tagged baculovirus Sf9 active 17.732510359115
10011564 HDAC1 Inhibitor Screening Assay Kit - 2008-04-10 19.383626677190 hdac1-inhibitor-screening-assay-kit HDAC 1 histones deacetylases lysines residues chromatin condensation transcriptional repression fluorescence deacetylation fluorescent inhibits inhibition enzymes license:cyclex fluorometric assays cancer 19.383626677190
13491 HDAC1 Polyclonal Antibody - 2009-07-24 3.400552486187 hdac1-polyclonal-antibody Histone Deactylase 1 HDAC-1 HDACs HDAC 1 antibodies WB western blots HATs immunoblotting blotting 3.400552486187
10009377 HDAC2 (human recombinant)