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Quercetin

Item № 10005169
CAS № 117-39-5
Purity ≥95%
product image
                (CAS 117-39-5)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     5 g $12.00 0.00
     10 g $23.00 0.00
     50 g $96.00 0.00
     100 g $168.00 0.00

Pricing updated 2019-07-17. Prices are subject to change without notice.

Description

Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties.1,2,3 Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) content, and increases total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy.2 It reduces tumor growth, induces apoptosis, and halts the cell cycle at the G1 phase in an HL60 mouse xenograft model when administered at a dose of 120 mg/kg every four days.1 Quercetin (30 µM) also inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of TNF-α, IL-1β, IL-6, and IL-8 induced by PMACI in HMC-1 cells.3

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Technical Information
Formal Name
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
CAS Number
117-39-5
Molecular Formula
C15H10O7
Formula Weight
302.2
Purity
≥95%
Formulation
A crystalline solid
SMILES
Oc1cc(O)c2c(c1)oc(c1ccc(O)c(O)c1)c(O)c2=O
InChI Code
InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
InChI Key
REFJWTPEDVJJIY-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Calgarotto, A.K., Maso, V., Junior, G.C.F., et al. Antitumor activities of quercetin and green tea in xenografts of human leukemia HL60 cells Sci. Rep. 8(1), 3459 (2018).

2. Yuan, Y., Ma, S., Qi, Y., et al. Quercetin inhibited cadmium-induced autophagy in the mouse kidney via inhibition of oxidative stress J. Toxicol. Pathol. 29(4), 247-252 (2016).

3. Park, H.H., Lee, S., Son, H.Y., et al. Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells Arch. Pharm. Res. 31(10), 1303-1311 (2008).

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