(±)11(12)-EET-d11 | Cayman Chemical
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Item № 10006413
Purity ≥99% deuterated forms (d1-d11)
product image
     10 µg $132.00 0.00
     25 µg $314.00 0.00
     50 µg $594.00 0.00
     100 µg $1,056.00 0.00

Pricing updated 2018-11-19. Prices are subject to change without notice.

  • (±)11,12-EET-d11

(±)11(12)-EET-d11 contains 11 deuterium atoms at the 16, 16', 17, 17', 18, 18', 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of (±)11(12)-DiHETrE by GC- or LC-mass spectrometry. (±)11(12)-EET (Item No. 50511) is biosynthesized from arachidonic acid in rat and rabbit liver microsomes by CYP450.1,2 (±)11(12)-EET has been shown, along with (±)8(9)-EET (Item No. 50351), to play a role in the recovery of depleted Ca2+ pools in cultured smooth muscle cells.3

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Technical Information
Formal Name
(±)11(12)-epoxy-5Z,8Z,14Z-eicosatrienoic-16,16,17,17,18,18,19,19,20,20,20 acid
  • (±)11,12-EET-d11
Molecular Formula
Formula Weight
≥99% deuterated forms (d1-d11)
A solution in ethanol
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Wet ice in continental US; may vary elsewhere
≥ 1 year
Downloads & Resources
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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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References & Product Citations
Product Description References

1. Chacos, N., Falck, J.R., Wixtrom, C., et al. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid Biochem. Biophys. Res. Commun. 104(3), 916-922 (1982).

2. Oliw, E.H., Guengerich, F.P., and Oates, J.A. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates J. Biol. Chem. 257(7), 3771-3781 (1982).

3. Graber, M.N., Alfonso, A., and Gill, D.L. Recovery of Ca2+ pools and growth in Ca2+ pool-depleted cells is mediated by specific epoxyeicosatrienoic acids derived from arachidonic acid J. Biol. Chem. 272(47), 29546-29553 (1997).

Technical Support

It appears that there is a heterogenous mixture of deuterated species in your deuterated standards; is this normal?

Yes, this is typical of our deuterated products. Our deuterated products contain less than 1 % d0. However, the labeled compounds are not 100% of the deuterated form listed on our product insert. For example, upon analysis of 2-arachidonoyl glycerol-d8 it is expected to see masses associated with the d7, d6, d5 etc.

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