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Estrone

Item № 10006485
CAS № 53-16-7
Purity ≥95%
product image
                (CAS 53-16-7)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     500 mg $8.00 0.00
     1 g $15.00 0.00
     5 g $64.00 0.00
     10 g $112.00 0.00

Pricing updated 2019-07-17. Prices are subject to change without notice.

Description
Synonyms
  • E1

Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol.1 Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver.1,2 Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women.1 The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.1

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Technical Information
Formal Name
3-hydroxy-estra-1,3,5(10)-trien-17-one
CAS Number
53-16-7
Synonyms
  • E1
Molecular Formula
C18H22O2
Formula Weight
270.4
Purity
≥95%
Formulation
A crystalline solid
λmax
281 nm
SMILES
Oc1ccc2c(CC[C@@H]3C2CC[C@]2(C)C(=O)CCC32)c1
InChI Code
InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1
InChI Key
DNXHEGUUPJUMQT-CBZIJGRNSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
Downloads & Resources
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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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References & Product Citations
Product Description References

1. Gruber, C.J., Tschugguel, W., Schneeberger, C., et al. Production and actions of estrogens New England Journal of Medicine 346(5), 340-352 (2002).

2. Vance, D.E. Cholesterol and related derivatives Biochemistry 2nd ed., 725-748 (1988).

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