FABP4 (human) EIA Kit

Item № 10007614
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
96 wells $782.00 0.00

Pricing updated 2018-02-18. Prices are subject to change without notice.

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Description
Features
  • Measure FABP4 in human serum, plasma, tissue extract, and culture supernatant
  • Assay 41 samples in duplicate
  • Incubations: 2 x 1 hour | 30 minutes
Synonyms
  • Adipocyte FABP
  • A-FABP
  • ALBP
  • aP2
  • Fatty Acid Binding Protein 4 (human) ELISA Kit

Fatty acid binding protein 4 (AFABP; adipocyte FABP; FABP4) is a 15 kDa member of the intracellular FABP family, which is known for the ability to bind fatty acids and related compounds (bile acids or retinoids). AFABP is expressed in a differentiation-dependent fashion in adipocytes and is a critical gene in the regulation of the biological function of these cells. In mice, targeted mutations in FABP4 (gene also called: aP2) provides significant protection from hyperinsulinemia and insulin resistance in the context of both dietary and genetic obesity. AFABP is also expressed in macrophages where it modulates inflammatory responses and cholesterol ester accumulation. Total or macrophage-specific FABP deficiency confers dramatic protection against atherosclerosis in apoE-/- mice. These results indicate a central role for AFABP in development of metabolic diseases through its distinct actions in adipocytes and macrophages. This Enzyme Immunometric Assay (EIA) is based on a double-antibody sandwich technique. The wells of the plate supplied with the kit are coated with a goat polyclonal antibody specific of human AFABP. This antibody will bind any human AFABP introduced in the wells (sample or standard). [Bertin Catalog No. A05181]

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
Synonyms
  • Adipocyte FABP
  • A-FABP
  • ALBP
  • aP2
  • Fatty Acid Binding Protein 4 (human) ELISA Kit
Specificity
  • (<0.1%) AFABP (chicken)
  • (<0.1%) AFABP (goat)
  • (<0.1%) AFABP (hamster)
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Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
4°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 6 months
Downloads & Resources
Product Downloads

Download Kit Booklet

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

Technical Support
Analysis Tools

View our analysis workbook for FABP4 (human) EIA Kit

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You may be eligible to receive a free sample of FABP4 (human) EIA Kit under the Cayman Challenge program.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

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