20-HETE Ethanolamide (CAS 942069-11-6) | Cayman Chemical
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20-HETE Ethanolamide

Item № 10008602
CAS № 942069-11-6
Purity ≥98%
product image
                (CAS 942069-11-6)
     25 µg $189.00 0.00
     50 µg $359.00 0.00
     100 µg $680.00 0.00

Pricing updated 2018-07-16. Prices are subject to change without notice.

  • 20-hydroxy AEA
  • 20-hydroxy Arachidonoyl Ethanolamide

Arachidonoyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity, binding both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.1,2 Fatty acid amide hydrolase (FAAH) is the enzyme responsible for the hydrolysis and inactivation of AEA.3 Metabolism of AEA by cyclooxygenase-2, leading to formation of prostaglandin ethanolamides, and by lipoxygenases has also been documented.4 20-HETE ethanolamide is a potential cytochrome P450 metabolite of arachidonoyl ethanolamide, which may be particularly relevant under conditions of fatty acid amide hydrolase inhibition. Evidence for the formation of 20-HETE ethanolamide in vivo has not been documented.

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Technical Information
Formal Name
CAS Number
  • 20-hydroxy AEA
  • 20-hydroxy Arachidonoyl Ethanolamide
Molecular Formula
Formula Weight
A solution in ethanol
210, 232 nm
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Wet ice in continental US; may vary elsewhere
≥ 1 year
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References & Product Citations
Product Description References

1. Felder, C.C., Briley, E.M., Axelrod, J., et al. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc. Natl. Acad. Sci. U.S.A. 90(16), 7656-7660 (1993).

2. Lambert, D.M., and Fowler, C.J. The endocannabinoid system: Drug targets, lead compounds, and potential therapeutic applications. Journal of Medicinal Chemistry 48(16), 5059-5087 (2005).

3. Deutsch, D.G., Ueda, N., and Yamamoto, S. The fatty acid amide hydrolase (FAAH). Prostaglandins, Leukotrienes and Essential Fatty Acids 66(2&3), 201-210 (2002).

4. Kozak, K.R., and Marnett, L.J. Oxidative metabolism of endocannabinoids. Prostaglandins, Leukotrienes and Essential Fatty Acids 66(2&3), 211-220 (2002).

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