20-HETE Ethanolamide (CAS 942069-11-6) | Cayman Chemical
We collect cookies for vital website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.

20-HETE Ethanolamide

Item № 10008602
CAS № 942069-11-6
Purity ≥98%
product image
                (CAS 942069-11-6)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     25 µg $189.00 0.00
     50 µg $359.00 0.00
     100 µg $680.00 0.00

Pricing updated 2018-07-16. Prices are subject to change without notice.

Description
Synonyms
  • 20-hydroxy AEA
  • 20-hydroxy Arachidonoyl Ethanolamide

Arachidonoyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity, binding both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.1,2 Fatty acid amide hydrolase (FAAH) is the enzyme responsible for the hydrolysis and inactivation of AEA.3 Metabolism of AEA by cyclooxygenase-2, leading to formation of prostaglandin ethanolamides, and by lipoxygenases has also been documented.4 20-HETE ethanolamide is a potential cytochrome P450 metabolite of arachidonoyl ethanolamide, which may be particularly relevant under conditions of fatty acid amide hydrolase inhibition. Evidence for the formation of 20-HETE ethanolamide in vivo has not been documented.

Recommended Products

Related Products
View Related Product Categories
View Screening Libraries with 20-HETE Ethanolamide
Technical Information
Formal Name
20-hydroxy-N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
CAS Number
942069-11-6
Synonyms
  • 20-hydroxy AEA
  • 20-hydroxy Arachidonoyl Ethanolamide
Molecular Formula
C22H37NO3
Formula Weight
363.5
Purity
≥98%
Formulation
A solution in ethanol
λmax
210, 232 nm
SMILES
OCCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO
InChI Code
InChI=1S/C22H37NO3/c24-20-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-22(26)23-19-21-25/h1,3-4,6-7,9-10,12,24-25H,2,5,8,11,13-21H2,(H,23,26)/b3-1-,6-4-,9-7-,12-10-
InChI Key
QRMZDMUHHZLRMH-DTLRTWKJSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
Product Downloads

Download Product Insert

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Felder, C.C., Briley, E.M., Axelrod, J., et al. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc. Natl. Acad. Sci. U.S.A. 90(16), 7656-7660 (1993).

2. Lambert, D.M., and Fowler, C.J. The endocannabinoid system: Drug targets, lead compounds, and potential therapeutic applications. Journal of Medicinal Chemistry 48(16), 5059-5087 (2005).

3. Deutsch, D.G., Ueda, N., and Yamamoto, S. The fatty acid amide hydrolase (FAAH). Prostaglandins, Leukotrienes and Essential Fatty Acids 66(2&3), 201-210 (2002).

4. Kozak, K.R., and Marnett, L.J. Oxidative metabolism of endocannabinoids. Prostaglandins, Leukotrienes and Essential Fatty Acids 66(2&3), 211-220 (2002).

Technical Support
Contact Us
  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Contract Research Services

We work with scientists to support their research, drug discovery, and drug development needs through our expertise in the following research services:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640