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JC-1 Mitochondrial Membrane Potential Assay Kit

Item № 10009172
     100 tests $198.00 0.00

Pricing updated 2019-07-21. Prices are subject to change without notice.

  • Measure mitochondrial membrane potential as an indicator of cell health
  • Utilizes JC-1, a fluorescent, lipophilic, cationic dye
  • Red fluorescence indicates healthy mitochondria and green fluorescence indicates mitochondria in poor health
  • Optimized for fluorescence microscopy or fluorescent plate readers. An assay optimized for flow cytometry is available under Item No. 701560.

Mitochondrial membrane potential, (ΔψM), is an important parameter of mitochondrial function used as an indicator of cell health. JC-1 is a lipophilic, cationic dye that can selectively enter into mitochondria and reversibly change color from green to red as the membrane potential increases. In healthy cells with high mitochondrial (ΔψM), JC-1 spontaneously forms complexes known as J-aggregates with intense red fluorescence. On the other hand, in apoptotic or unhealthy cells with low (ΔψM), JC-1 remains in the monomeric form, which shows only green fluorescence. Cayman’s JC-1 Mitochondrial Membrane Potential Assay Kit provides all the necessary reagents, as well as complete instructions, for analysis of mitochondrial integrity in whole cells. The assay is applicable to fluorescence microscopy and fluorescent plate reader. For flow cytometry, Cayman’s JC-1 Mitochondrial Membrane Potential Flow Cytometry Assay Kit (Item No. 701560) is recommended.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information

Warning - this product is not for human or veterinary use.

Shipping & Storage
Wet ice in continental US; may vary elsewhere
≥ 1 year
Downloads & Resources
Product Downloads

Download Kit Booklet

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

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