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(+)-Cloprostenol isopropyl ester

Item № 10010016
CAS № 157283-66-4
Purity ≥98%
product image
                (CAS 157283-66-4)
     1 mg $58.00 0.00
     5 mg $261.00 0.00
     10 mg $464.00 0.00

Pricing updated 2019-07-17. Prices are subject to change without notice.

  • (+)-5-cis Cloprostenol isopropyl ester
  • (+)-16-m-chlorophenoxy tetranor Prostaglandin F isopropyl ester

(+)-Cloprostenol is a synthetic analog of prostaglandin F (PGF). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF in terminating pregnancy when given subcutaneously at a daily dose of 0.125 μg/kg in rats and hamsters, without the side effects associated with PGF.1 (+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3 x 10-12 M.2 (+)-Cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol.

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Technical Information
Formal Name
(+)-9α,11α,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester
CAS Number
  • (+)-5-cis Cloprostenol isopropyl ester
  • (+)-16-m-chlorophenoxy tetranor Prostaglandin F isopropyl ester
Molecular Formula
Formula Weight
A solution in ethanol
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Wet ice in continental US; may vary elsewhere
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F Nature 250(464), 330-331 (1974).

2. Serrero, G., and Lepak, N.M. Prostaglandin F receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium Biochemical and Biophysical Research Communications 233(1), 200-202 (1997).

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