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Item № 10011659
CAS № 53188-07-1
Purity ≥98%
product image
                (CAS 53188-07-1)
     250 mg $25.00 0.00
     500 mg $38.00 0.00
     1 g $55.00 0.00

Pricing updated 2019-04-25. Prices are subject to change without notice.

  • 6-hydroxy-2,5,7,8-tetramethylchroman-2-Carboxylic Acid

Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties. It is commonly used as a standard or positive control in antioxidant assays.1,2 In addition, trolox is used to assess the role of oxidative injury in processes like neuronal cell death and aging.3,4 Trolox is effective as adjunctive therapy in the treatment of certain cancers.5

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Technical Information
Formal Name
3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
CAS Number
  • 6-hydroxy-2,5,7,8-tetramethylchroman-2-Carboxylic Acid
Molecular Formula
Formula Weight
A crystalline solid
291 nm
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 2 years
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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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References & Product Citations
Product Description References

1. Cos, P., Hermans, N., Calomme, M., et al. Comparative study of eight well-known polyphenolic antioxidants Journal of Pharmacy and Pharmacology 55, 1291-1297 (2003).

2. Tadolini, B., Juliano, C., Piu, L., et al. Resveratrol inhibition of lipid peroxidation Free Radical Research 33, 105-114 (2000).

3. Jang, H.J., Hwang, S., Cho, K.Y., et al. Taxol induces oxidative neuronal cell death by enhancing the activity of NADPH oxidase in mouse cortical cultures Neuroscience Letters 443, 17-22 (2008).

4. Benedetti, M.G., Foster, A.L., Vantipalli, M.C., et al. Compounds that confer thermal stress resistance and extended lifespan Experimental Gerontology 43, 882-891 (2008).

5. Diaz, Z., Laurenzana, A., Mann, K.K., et al. Trolox enhances the anti-lymphoma effects of arsenic trioxide, while protecting against liver toxicity Leukemia 21, 2117-2127 (2007).

Product Citations

Hajmousa, G., Vogelaar, P., Brouwer, L.A., et al. The 6-chromanol derivate SUL-109 enables prolonged hypothermic storage of adipose tissue-derived stem cells Biomaterials 119, 43-52 (2017).

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