Trolox (CAS 53188-07-1) | Cayman Chemical
We collect cookies for vital website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.

Trolox

Item № 10011659
CAS № 53188-07-1
Purity ≥98%
product image
                (CAS 53188-07-1)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     250 mg $25.00 0.00
     500 mg $38.00 0.00
     1 g $55.00 0.00

Pricing updated 2018-11-16. Prices are subject to change without notice.

Description
Synonyms
  • 6-hydroxy-2,5,7,8-tetramethylchroman-2-Carboxylic Acid

Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties. It is commonly used as a standard or positive control in antioxidant assays.1,2 In addition, trolox is used to assess the role of oxidative injury in processes like neuronal cell death and aging.3,4 Trolox is effective as adjunctive therapy in the treatment of certain cancers.5

Recommended Products

Related Products
View Related Product Categories
Technical Information
Formal Name
3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
CAS Number
53188-07-1
Synonyms
  • 6-hydroxy-2,5,7,8-tetramethylchroman-2-Carboxylic Acid
Molecular Formula
C14H18O4
Formula Weight
250.3
Purity
≥98%
Formulation
A crystalline solid
λmax
291 nm
SMILES
Cc1c2OC(C)(CCc2c(C)c(O)c1C)C(=O)O
InChI Code
InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
InChI Key
GLEVLJDDWXEYCO-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
Downloads & Resources
Product Downloads

Download Product Insert

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Cos, P., Hermans, N., Calomme, M., et al. Comparative study of eight well-known polyphenolic antioxidants Journal of Pharmacy and Pharmacology 55, 1291-1297 (2003).

2. Tadolini, B., Juliano, C., Piu, L., et al. Resveratrol inhibition of lipid peroxidation Free Radical Research 33, 105-114 (2000).

3. Jang, H.J., Hwang, S., Cho, K.Y., et al. Taxol induces oxidative neuronal cell death by enhancing the activity of NADPH oxidase in mouse cortical cultures Neuroscience Letters 443, 17-22 (2008).

4. Benedetti, M.G., Foster, A.L., Vantipalli, M.C., et al. Compounds that confer thermal stress resistance and extended lifespan Experimental Gerontology 43, 882-891 (2008).

5. Diaz, Z., Laurenzana, A., Mann, K.K., et al. Trolox enhances the anti-lymphoma effects of arsenic trioxide, while protecting against liver toxicity Leukemia 21, 2117-2127 (2007).

Technical Support
Contact Us
  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Cayman Contract Services

We work with scientists to accelerate their research, drug discovery, and drug development needs through our expertise in the following areas:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640