Sampling Tubes with PHMB | Cayman Chemical
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Sampling Tubes with PHMB

Item № 10949
     35 ea $201.00 0.00
     100 ea $516.00 0.00

Pricing updated 2018-11-17. Prices are subject to change without notice.

This product has been produced by
  • For storing cysteine protease-sensitive samples
  • Contains the cysteine protease inhibitor PHMB (1 mM final concentration)
  • 4-(hydroxymercuri)Benzoic Acid

4-(hydroxymercuri)Benzoic Acid(PHMB) is used to inhibit cysteine-protease and acts as a reversible thiol-specific blocker. While blocking the acylated ghrelin degradation, it allows the AcetylCholine Esterase AChE™ used in SPI-Bio EIA kits to work normally, in contrast to serine-protease inhibitors. Neuropeptides and other short peptides are really sensitive to protease degradation. It is often necessary to add specific and potent inhibitors to avoid total loss of the biomarker. The PHMB containing tubes have been designed to accept 1 ml samples. The cryotubes are graduated, with a silicone washer seal and external threads. They can be stored at temperatures as low as -196°C but should be used only in the gas phase of liguid nitrogen. Thus, PHMB sampling tubes may be useful to measure any biomarker cleaved by cysteine-proteases.1 [Bertin Catalog No. D31009]

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
  • 4-(hydroxymercuri)Benzoic Acid

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature
Ambient in continental US; may vary elsewhere
≥ 1 year
Downloads & Resources
Product Downloads

Download Kit Booklet

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Boyer, P.D. Spectrophotometric study of the reaction of protein sulfhydryl groups with organic mercurials Journal of American Chemistry Society 76(17), 4331-4337 (1954).

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