Pricing updated 2019-05-23. Prices are subject to change without notice.
Boswellic acids are pentacyclic triterpenes first isolated from the resin of Boswellia plants. They have anti-inflammatory and anti-arthritic actions in mice.1,2 β-acetyl-Boswellic acid is a non-reducing inhibitor of 5-lipoxygenase (5-LO) that shows selectivity for 5-LO over 12-LO or COX.3,4 When studied as a 1:1 mixture with α-acetyl-boswellic acid, it inhibits topoisomerase II activity and arrests cell cycling or induces apoptosis in cancer cells.5,6
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1. Wang, Q., Pan, X., Wong, H.H., et al. Oral and topical boswellic acid attenuates mouse osteoarthritis Osteoarthritis Cartilage 22(1), 128-132 (2014).
Mostafa, D.M., Ammar, N.M., Basha, M., et al. Transdermal microemulsions of Boswellia carterii Bird: Formulation, characterization and in vivo evaluation of anti-
Safayhi, H., Mack, T., Sabieraj, J., et al. Boswellic acids: Novel, specific, nonredox inhibitors of 5-
4. Ammon, H.P., Safayhi, H., Mack, T., et al. Mechanism of antiinflammatory actions of curcumine and boswellic acids J. Ethnopharmacol. 38(2-3), 113-119 (1993).
5. Zhao, W., Entschladen, F., Liu, H., et al. Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells Cancer Detection and Prevention 27(1), 67-75 (2003).
Xia, L., Chen, D., Han, R., et al. Boswellic acid acetate induces apoptosis through caspase-