We collect cookies for vital website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.

β-acetyl-Boswellic Acid

Item № 11674
CAS № 5968-70-7
Purity ≥95%
product image
                (CAS 5968-70-7)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $29.00 0.00
     5 mg $116.00 0.00
     10 mg $218.00 0.00

Pricing updated 2019-05-23. Prices are subject to change without notice.

Description
Synonyms
  • ABA
  • 3-O-acetyl-β-Boswellic acid
  • β-Boswellic acid acetate

Boswellic acids are pentacyclic triterpenes first isolated from the resin of Boswellia plants. They have anti-inflammatory and anti-arthritic actions in mice.1,2 β-acetyl-Boswellic acid is a non-reducing inhibitor of 5-lipoxygenase (5-LO) that shows selectivity for 5-LO over 12-LO or COX.3,4 When studied as a 1:1 mixture with α-acetyl-boswellic acid, it inhibits topoisomerase II activity and arrests cell cycling or induces apoptosis in cancer cells.5,6

Recommended Products

Related Products
View Related Product Categories
Technical Information
Formal Name
(3α,4β)-3-(acetyloxy)-urs-12-en-23-oic acid
CAS Number
5968-70-7
Synonyms
  • ABA
  • 3-O-acetyl-β-Boswellic acid
  • β-Boswellic acid acetate
Molecular Formula
C32H50O4
Formula Weight
498.7
Purity
≥95%
Formulation
A crystalline solid
SMILES
C[C@]1(C(O)=O)[C@H](OC(C)=O)CC[C@]2(C)[C@@]3([H])CC=C4[C@](CC[C@]5(C)[C@@]4([H])[C@@H](C)[C@H](C)CC5)(C)[C@]3(C)CC[C@]21[H]
InChI Code
InChI=1S/C32H50O4/c1-19-11-14-28(4)17-18-30(6)22(26(28)20(19)2)9-10-23-29(5)15-13-25(36-21(3)33)32(8,27(34)35)24(29)12-16-31(23,30)7/h9,19-20,23-26H,10-18H2,1-8H3,(H,34,35)/t19-,20+,23-,24-,25-,26+,28-,29-,30-,31-,32?/m1/s1
InChI Key
YJBVHJIKNLBFDX-MWEIDVNDSA-N
Origin
  • Plant/Boswelli aserrata

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
Downloads & Resources
Product Downloads

Download Product Insert

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Wang, Q., Pan, X., Wong, H.H., et al. Oral and topical boswellic acid attenuates mouse osteoarthritis Osteoarthritis Cartilage 22(1), 128-132 (2014).

2. Mostafa, D.M., Ammar, N.M., Basha, M., et al. Transdermal microemulsions of Boswellia carterii Bird: Formulation, characterization and in vivo evaluation of anti-inflammatory activity Drug Deliv. 22(6), 748-756 (2015).

3. Safayhi, H., Mack, T., Sabieraj, J., et al. Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase J. Pharmacol. Exp. Ther. 261(3), 1143-1146 (1992).

4. Ammon, H.P., Safayhi, H., Mack, T., et al. Mechanism of antiinflammatory actions of curcumine and boswellic acids J. Ethnopharmacol. 38(2-3), 113-119 (1993).

5. Zhao, W., Entschladen, F., Liu, H., et al. Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells Cancer Detection and Prevention 27(1), 67-75 (2003).

6. Xia, L., Chen, D., Han, R., et al. Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells Molecular Cancer Therapeutics 4(3), 381-388 (2005).

Technical Support
Contact Us
  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Cayman Contract Services

We work with scientists to accelerate their research, drug discovery, and drug development needs through our expertise in the following areas:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640