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UR-144 Degradant

Item № 11928
CAS № 1609273-88-2
Purity ≥98%
product image
                (CAS 1609273-88-2)

Formulation:  A solution in methanol

     1 mg $95.00 0.00
     5 mg $261.00 0.00
     10 mg $475.00 0.00

Pricing updated 2019-05-26. Prices are subject to change without notice.

  • KM-X1 Degradant
  • UR-144 3,3,4-Trimethylpentenoyl isomer

UR-144 (Item No. 11502) is a synthetic cannabinoid (CB) analog of JWH 018 (Item No. 10900) in which the naphthalene ring is substituted with a tetramethylcyclopropyl group. This substitution results in a compound which is a potent agonist for the peripheral CB2 receptor.1 UR-144 Degradant is a common impurity observed during GC-MS analysis of samples containing UR-144. The opened ring of the degradant is presumed to be produced during heating of UR-144. This structure gives rise to a prominent fragment ion that is 15 amu greater than the base peak of UR-144. This pattern is consistent with McLafferty rearrangement of the degradant which does not occur with the parent compound.2

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Technical Information
Formal Name
CAS Number
  • KM-X1 Degradant
  • UR-144 3,3,4-Trimethylpentenoyl isomer
Molecular Formula
Formula Weight
A solution in methanol
213, 247, 305 nm
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 1 year
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References & Product Citations
Product Description References

1. Frost, J.M., Dart, M.J., Tietje, K.R., et al. Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB2 cannabinoid receptor activity J. Med. Chem. 53(1), 295-315 (2010).

2. McLafferty, F.W. Mass spectrometric analysis. Molecular rearrangements Analytical Chemistry 31(1), 82-87 (1959).

Product Citations

Thomas, B.F., Lefever, T.W., Cortes, R.A., et al. Thermolytic degradation of synthetic cannabinoids: Chemical exposures and pharmacological consequences J. Pharmacol. Exp. Ther. 361(1), 162-171 (2017).

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