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Pro-drug Form(s)
9004470(+)-Etomoxir
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(+)-Etomoxir (sodium salt)

Item No. 11969

Technical Information
CAS Number
828934-41-4
Synonyms
  • (R)-(+)-Etomoxir
Formula Weight
320.7
DMF: 10 mg/mlDMSO: 5 mg/mlEthanol: 5 mg/mlWater: 10 mg/ml (ultrasonic)Water: 15 mg/ml (ultrasonic at 36°C)
λmax
229,282 nm
SMILES
[O-]C([C@]1(CCCCCCOC2=CC=C(Cl)C=C2)OC1)=O.[Na+]
InChi Code
InChI=1S/C15H19ClO4.Na/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;/h5-8H,1-4,9-11H2,(H,17,18);/q;+1/p-1/t15-;/m1./s1
InChi Key
RPACBEVZENYWOL-XFULWGLBSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Das, S., Finney, A.C., Anand, S.K., et al. Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis. Nat. Metab. 6(10), 1939-1962 (2024).

    Hwang, S.W., Adiyaman, M., Khanapure, S., et al. Total synthesis of 8-epi-PGF2α. A novel strategy for the synthesis of isoprostanes. J. Am. Chem. Soc. 116(23), 10829-10830 (1994).

    Onodera, T., Wang, M.-Y., Rutkowski, J.M., et al. Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization. Nat. Commun. 14(1), 6531 (2023).

    Li, H., Dixon, E.E., Wu, H., et al. Comprehensive single-cell transcriptional profiling defines shared and unique epithelial injury responses during kidney fibrosis. Cell Metab. 34(12), 1977-1998 (2022).

    Patel, R., Santoro, A., Hofer, P., et al. ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids. Nature (2021).

    Singh, S.R., Zeng, X., Zhao, J., et al. The lipolysis pathway sustains normal and transformed stem cells in adult Drosophila. Nature 538(7623), 109-113 (2016).