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L-DOPA

Item № 13248
CAS № 59-92-7
Purity ≥95%
product image
                (CAS 59-92-7)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     5 g $14.00 0.00
     25 g $63.00 0.00
     50 g $112.00 0.00
     100 g $196.00 0.00

Pricing updated 2019-04-24. Prices are subject to change without notice.

Description
Synonyms
  • 3,4-Dihydroxyphenylalanine
  • Levodopa

Dopamine is a neurotransmitter involved in synaptic plasticity, cognition, and the regulation of locomotor control. It is produced endogenously in the substantia nigra and ventral tegmental area but when administered exogenously cannot cross the blood brain barrier. L-DOPA is a metabolic precursor of dopamine that is capable of crossing the blood brain barrier.1 It is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). In the brain L-DOPA is converted to dopamine. Formulations containing L-DOPA have been used to increase dopamine concentrations in the brain as a treatment for Parkinson’s disease and stroke recovery.

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Technical Information
Formal Name
3-hydroxy-L-tyrosine
CAS Number
59-92-7
Synonyms
  • 3,4-Dihydroxyphenylalanine
  • Levodopa
Molecular Formula
C9H11NO4
Formula Weight
197.2
Purity
≥95%
Formulation
A crystalline solid
SMILES
OC1=CC(C[C@H](N)C(O)=O)=CC=C1O
InChI Code
InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)
InChI Key
WTDRDQBEARUVNC-UHFFFAOYSA-N
Origin
  • Synthetic

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
Downloads & Resources
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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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References & Product Citations
Product Description References

1. Berends, H.I., Nijlant, J.M.M., Movig, K.L.L., et al. The clinical use of drugs influencing neurotransmitters in the brain to promote motor recovery after stroke; a Cochrane systematic review Eur. J. Phys. Rehabil. Med. 45(4), 621-630 (2009).

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