A dopamine precursor
Related Products
Active Metabolite(s)
364433-Methoxytyrosine
Enantiomer(s)
13249D-DOPA
Isomer(s)
36382Forphenicinol
Labeled Version(s)
22089L-DOPA-d3
Metabolite(s)
207373-O-methyl-L-DOPA (hydrate)
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L-DOPA

Item No. 13248

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-hydroxy-L-tyrosine
CAS Number
59-92-7
Synonyms
  • 3,4-Dihydroxyphenylalanine
  • Levodopa
Molecular Formula
C9H11NO4
Formula Weight
197.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
SMILES
OC1=CC(C[C@H](N)C(O)=O)=CC=C1O
InChi Code
InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)
InChi Key
WTDRDQBEARUVNC-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $28

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    25 g

    $104

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    50 g

    $180

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    100 g

    $303

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    Product Description

    L-DOPA is a metabolic precursor of dopamine that is capable of crossing the blood-brain barrier.1 It is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). In the brain L-DOPA is converted to dopamine. Formulations containing L-DOPA have been used in stroke recovery and in the treatment of Parkinson's disease.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Berends, H.I., Nijlant, J.M.M., Movig, K.L.L., et al. The clinical use of drugs influencing neurotransmitters in the brain to promote motor recovery after stroke; a Cochrane systematic review. Eur. J. Phys. Rehabil. Med. 45(4), 621-630 (2009).