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Item № 14915
CAS № 16837-52-8
Purity ≥98%
product image
                (CAS 16837-52-8)
     50 mg $39.00 0.00
     100 mg $66.00 0.00
     500 mg $137.00 0.00
     1 g $195.00 0.00

Pricing updated 2019-06-26. Prices are subject to change without notice.

  • Matrine 1-oxide

Oxymatrine is a natural alkaloid isolated from the root of S. flavescens, an herb used in traditional Chinese herbal medicine.1 It has antiviral properties, inhibiting the replication of hepatitis B alone and in combination with lamivudine.2,3 Oxymatrine also prevents fibrosis in a number of organs including liver, at least in part by interfering with TGF-β signaling.4,5 This compound also induces apoptosis in certain cancer cells and ameliorates inflammation by impairing the translocation of nuclear factors-κB.1,6

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Technical Information
Formal Name
CAS Number
  • Matrine 1-oxide
Molecular Formula
Formula Weight
A crystalline solid
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 2 years
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References & Product Citations
Product Description References

1. Ling, Q., Xu, X., Wei, X., et al. Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c J.Exp.Clin.Cancer Res. 30, 66 (2011).

2. Cui, X., Wang, Y., Kokudo, N., et al. Traditional Chinese medicine and related active compounds against hepatitis B virus infection Biosci.Trends 4(2), 39-47 (2010).

3. Ma, Z.J., Li, Q., Wang, J.B., et al. Combining oxymatrine or matrine with lamivudine increased its antireplication effect against the hepatitis B virus in vitro Evidence-Based Complementary and alternative Medicine 2013, 186573 (2013).

4. Chai, N.L., Fu, Q., Shi, H., et al. Oxymatrine liposome attenuates hepatic fibrosis via targeting hepatic stellate cells World Journal of Gastroenterology 18(31), 4199-4206 (2012).

5. Wu, X.L., Zeng, W.Z., Jiang, M.D., et al. Effect of oxymatrine on the TGβSmad signaling pathway in rats with CCl4-induced hepatic fibrosis World Journal of Gastroenterology 14(13), 2100-2105 (2008).

6. Guzman, J.R., Koo, J.S., Goldsmith, J.R., et al. Oxymatrine prevents NF-κB nuclear translocation and ameliorates acute intestinal inflammation Sci.Rep. 3, 1629 (2013).

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