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Mepirapim (hydrochloride)

Item No. 15388

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • JWH 018-4(methylpiperazine)
Technical Information
Formal Name
(4-methyl-1-piperazinyl)(1-pentyl-1H-indol-3-yl)-methanone, monohydrochloride
CAS Number
2365542-30-7
Molecular Formula
C19H27N3O • HCl
Formula Weight
349.9
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 25 mg/mlEthanol: 30 mg/mlMethanol: 1 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
218, 289 nm
SMILES
CCCCCN1C=C(C(N2CCN(C)CC2)=O)C3=CC=CC=C31.Cl
InChi Code
InChI=1S/C19H27N3O.ClH/c1-3-4-7-10-22-15-17(16-8-5-6-9-18(16)22)19(23)21-13-11-20(2)12-14-21;/h5-6,8-9,15H,3-4,7,10-14H2,1-2H3;1H
InChi Key
PAIPEAYSOQABHT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    JWH 018 (Item No. 10900) is a potent synthetic cannabinoid (CB) that avidly binds both the central CB1 receptor and the peripheral CB2 receptor (Kis = 9.0 and 2.9 nM, respectively).1 Structurally, JWH 018 is an aminoalkylindole with a naphthoyl group. Mepirapim is an analog of JWH 018 that has been identified in herbal blends in Japan.2 It differs from JWH 018 by having a 4-methylpiperazine group in place of the naphthyl group. The physiological and toxicological properties of this compound are unknown. This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60(2), 133-140 (2000).

    2. Uchiyama, N., Shimokawa, Y., Matsuda, S., et al. Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products. Forensic Toxicol. (2013).

    Product Citations

    Mochizuki, A., Nakazawa, H., Adachi, N., et al. Identification and quantification of mepirapim and acetyl fentanyl in authentic human whole blood and urine samples by GC-MS/MS and LC-MS/MS. Forensic Toxicol. 36, 81-87 (2018).