PAF C-16 Carboxylic Acid (CAS 129879-41-0) | Cayman Chemical
We collect cookies for vital website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.

PAF C-16 Carboxylic Acid

Item № 15392
CAS № 129879-41-0
Purity ≥95%
product image
                (CAS 129879-41-0)
     500 µg $99.00 0.00
     1 mg $188.00 0.00
     5 mg $792.00 0.00
     10 mg Contact us

Pricing updated 2018-12-11. Prices are subject to change without notice.

  • Platelet-activating Factor C-16 Carboxylic Acid

PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and 'de novo' pathways.1 It is a potent mediator of neutrophil migration and the production of reactive oxygen species and IL-6.2,3,4 Pathological processes involving PAF include necrotizing enterocolitis, inflammation, asthma, and allergy.5,6 PAF C-16 Carboxylic acid is modified with a carboxylic acid group terminating the C-16 alkyl chain. This provides a convenient site for chemical crosslinking.

Recommended Products

Related Products
View Related Product Categories
Technical Information
Formal Name
(R)-7-(acetyloxy)-24-carboxy-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphatetracosan-1-aminium, inner salt, 4-oxide
CAS Number
  • Platelet-activating Factor C-16 Carboxylic Acid
Molecular Formula
Formula Weight
A solution in ethanol
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 1 year
Downloads & Resources
Product Downloads

Download Product Insert

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Prescott, S.M., Zimmerman, G.A., and McIntyre, T.M. Platelet-activating factor The Journal of Biological Chemisty 265, 17381-17384 (1990).

2. Carolan, E.J., and Casale, T.B. Degree of platelet activating factor-induced neutrophil migration is dependent upon the molecular species Journal of Immunology 145, 2561-2565 (1990).

3. Rouis, M., Nigon, F., and Chapman, M.J. Platelet activating factor is a potent stimulant of the production of active oxygen species by human monocyte-derived macrophages Biochemical and Biophysical Research Communications 156, 1293-1301 (1988).

4. Thivierge, M., and Rola-Pleszczynski, M. Platelet-activating factor enhances interleukin-6 production by alveolar macrophages Journal of Allergy and Clinical Immunology 90, 796-802 (1992).

5. Wang, H., Tan, X.D., Qu, X.W., et al. Platelet-activating factor (PAF) up-regulates plasma and tissue PAF-acetylhydrolase activity in the rat: Effect of cycloheximide Pediatric Research 42, 597-603 (1997).

6. Sturk, A., Wouter Ten Cate, J., Hosford, D., et al. The synthesis, catabolism, and pathophysiological role of platelet-activating factor Advances in Lipid Research 23, 219-276 (1989).

Technical Support
Contact Us
  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Cayman Contract Services

We work with scientists to accelerate their research, drug discovery, and drug development needs through our expertise in the following areas:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640