Glufosinate (ammonium salt) (CAS 77182-82-2) | Cayman Chemical
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Glufosinate (ammonium salt)

Item № 16675
CAS № 77182-82-2
Purity ≥95%
product image
                (CAS 77182-82-2)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     50 mg $25.00 0.00
     100 mg $38.00 0.00
     250 mg $81.00 0.00
     1 g $250.00 0.00

Pricing updated 2018-11-19. Prices are subject to change without notice.

Description
Synonyms
  • Basta®
  • HOE 00661
  • HOE 39866

Glufosinate is a racemic mixture of D- and L-phosphinothricin. L-Phosphinothricin is a naturally-occurring bacterial amino acid that irreversibly inhibits glutamine synthetase (GS), resulting in death in green plants.1 The ammonium salt of glufosinate is widely known as phosphinothricin, or PPT, and used as the active ingredient in broad-spectrum herbicides.1,2 Phosphinothricin acetyltransferase, encoded by the bar gene, converts PPT to a GS-inactive form. As a result, the bar gene is used as a selectable marker for genetic engineering in plants.3 As it confers resistance to the herbicide glufosinate rather than to an antibiotic, the bar gene may be preferred for selection of components for biological therapies, such as vaccines.4

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Technical Information
Formal Name
2-amino-4-(hydroxymethylphosphinyl)-butanoic acid, monoammonium salt
CAS Number
77182-82-2
Synonyms
  • Basta®
  • HOE 00661
  • HOE 39866
Molecular Formula
C5H11NO4P • NH4
Formula Weight
198.2
Purity
≥95%
Formulation
A crystalline solid
SMILES
OC(C(CCP(C)([O-])=O)N)=O.[NH4+]
InChI Code
InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3
InChI Key
ZBMRKNMTMPPMMK-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Duke, S.O., Cantrell, C.L., Meepagala, K.M., et al. Natural toxins for use in pest management Toxins (Basel) 2(8), 1943-1962 (2010).

2. Nair, S.K., and van der Donk, W.A. Structure and mechanism of enzymes involved in biosynthesis and breakdown of the phosphonates fosfomycin, dehydrophos, and phosphinothricin Archives of Biochemistry and Biophysics 505(1), 13-21 (2011).

3. Block, M.D., Botterman, J., Vandewiele, M., et al. Engineering herbicide resistance in plants by expression of a detoxifying enzyme EMBO Journal 6(9), 2513-2518 (1987).

4. McNeill, H.V., Sinha, K.A., Hormaeche, C.E., et al. Development of a nonantibiotic dominant marker for positively selecting expression plasmids in multivalent Salmonella vaccines Applied and Environmental Microbiology 66(3), 1216-1219 (2000).

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