Pricing updated 2018-11-16. Prices are subject to change without notice.
Pantothenic acid (vitamin B5) is a precursor in the biosynthesis of coenzyme A (Item No. 16147), which is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism.1,2 Two enantiomers of pantothenic acid exist, D- or L-form. D-Pantothenic acid (sodium salt) is a sodium salt form of the biologically active enantiomer of vitamin B5 and is used in the synthesis of coenzyme A.3 The L-form of pantothenic acid is biologically inactive and has been shown to act as an antagonist of D-pantothenic acid.4
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1. Jackowski, S. Biosynthesis of pantothenic acid and coenzyme A Escherichia coli and Salmonella typhimurium: Cellular and molecular biology 687-694 (1996).
2. Leonardi, R., Zhang, Y.M., Rock, C.O., et al. Coenzyme A: Back in action Progress in Lipid Research 44(2-3), 125-153 (2005).
Shibata, K., Kaneko, M., and Fukuwatari, T. D-
4. Kimura, S., Furukawa, Y., Wakasugi, J.i., et al. Antagonism of L(−)pantothenic acid on lipid metabolism in animals J.Nutr.Sci.Vitaminol.(Tokyo) 26(2), 113-117 (1980).