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Formononetin

Item № 17558
CAS № 485-72-3
Purity ≥98%
product image
                (CAS 485-72-3)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     5 mg $25.00 0.00
     10 mg $45.00 0.00
     25 mg $106.00 0.00
     100 mg $350.00 0.00

Pricing updated 2019-07-23. Prices are subject to change without notice.

Description
Synonyms
  • Biochanin B
  • NSC 93360

Formononetin is an isoflavonoid phytoestrogenic compound found in soy-based foods and is the precursor of daidzein (Item No. 10005166).1 It acts as an agonist of the aryl hydrocarbon receptor with an EC50 value of 0.13 µM.2 Formononetin has been reported to possess antitumor and antiviral activity.3,4

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Technical Information
Formal Name
7-hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one
CAS Number
485-72-3
Synonyms
  • Biochanin B
  • NSC 93360
Molecular Formula
C16H12O4
Formula Weight
268.3
Purity
≥98%
Formulation
A crystalline solid
λmax
249, 301 nm
SMILES
OC1=CC=C(C(C(C2=CC=C(OC)C=C2)=CO3)=O)C3=C1
InChI Code
InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3
InChI Key
HKQYGTCOTHHOMP-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
Downloads & Resources
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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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References & Product Citations
Product Description References

1. Patisaul, H.B., and Jefferson, W. The pros and cons of phytoestrogens Front.Neuroendocrinol. 31(4), 400-419 (2010).

2. Medjakovic, S., and Jungbauer, A. Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptor Journal of Steroid Biochemistry and Molecular Biology 108(1-2), 171-177 (2008).

3. Yang, Y., Zhao, Y., Ai, X., et al. Formononetin suppresses the proliferation of human non-small cell lung cancer through induction of cell cycle arrest and apoptosis Int.J.Clin.Exp.Pathol. 7(12), 8453-8461 (2014).

4. Wang, H., Zhang, D., Ge, M., et al. Formononetin inhibits enterovirus 71 replication by regulating COX-2/PGE2 expression Virol.J. 12:35, 1-10 (2015).

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