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Item № 17803
Purity ≥99% deuterated forms (d1-d3)
product image
     500 µg $139.00 0.00
     1 mg $250.00 0.00

Pricing updated 2019-07-18. Prices are subject to change without notice.

  • VRC-d3

Voriconazole-d3 contains three deuterium atoms located on the β methyl group. It is intended for use as an internal standard for the quantification of voriconazole (Item No. 15633) by GC- or LC-mass spectrometry. Voriconazole is a triazole, antifungal agent that inhibits a broad range of pathogenic yeasts, including Candida (MIC = 0.03-8 µg/ml), and filamentous fungi such as Aspergillus, Scedosporium, and Fusarium.1,2 Its inhibitory action results from its ability to inhibit the synthesis of ergosterol, the major sterol of the fungal cell membrane.2,3,4

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Technical Information
Formal Name
  • VRC-d3
Molecular Formula
Formula Weight
≥99% deuterated forms (d1-d3)
A crystalline solid
205, 255 nm
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 2 years
Downloads & Resources
Product Downloads

Download Product Insert

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Herbrecht, R., Nivoix, Y., Fohrer, C., et al. Management of systemic fungal infections: Alternatives to itraconazole J. Antimicrob. Chemother. 56(Suppl 1), i39-i48 (2005).

2. Delattin, N., Cammue, B.P.A., and Thevissen, K. Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms Future Med.Chem. 6(1), 77-90 (2014).

3. Munayyer, H.K., Mann, P.A., Chau, A.S., et al. Posaconazole is a potent inhibitor of sterol 14α-demethylation in yeasts and molds Antimicrobial Agents and Chemotherapy 48(10), 3690-3696 (2004).

4. Warrilow, A.G., Melo, N., Martel, C.M., et al. Expression, purification, and characterization of Aspergillus fumigatus sterol 14-a demethylase (CYP51) isoenzymes A and B Antimicrob. Agents Chemother. 54(10), 4225-4234 (2010).

Technical Support

It appears that there is a heterogenous mixture of deuterated species in your deuterated standards; is this normal?

Yes, this is typical of our deuterated products. Our deuterated products contain less than 1 % d0. However, the labeled compounds are not 100% of the deuterated form listed on our product insert. For example, upon analysis of 2-arachidonoyl glycerol-d8 it is expected to see masses associated with the d7, d6, d5 etc.

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