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Item № 18626
CAS № 51-43-4
Purity ≥95%
product image
                (CAS 51-43-4)
     5 g $49.00 0.00
     10 g $93.00 0.00
     25 g $221.00 0.00

Pricing updated 2019-07-17. Prices are subject to change without notice.

  • Adrenaline
  • NSC 62786

(-)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for α1A-, β2-, and β1-adrenergic receptors, respectively).1,2,3 Through these receptors, (-)-epinephrine may induce either contraction or relaxation of vascular smooth muscle, depending on adrenoceptor subtype expression.3 Receptor-mediated actions of (-)-epinephrine are also relevant to blocking anaphylaxis, reversing cardiac arrest, and reducing bleeding in clinical trials.4,5,6

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Technical Information
Formal Name
CAS Number
  • Adrenaline
  • NSC 62786
Molecular Formula
Formula Weight
A crystalline solid
281 nm
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Rothman, R.B., Vu, N., Partilla, J.S., et al. In vitro characterization of ephedrine-related stereoisomers at biogenic amine transporters and the receptorome reveals selective actions as norepinephrine transporter substrates J. Pharmacol. Exp. Ther. 307(1), 138-145 (2003).

2. Hoffmann, C., Leitz, M.R., Oberdorf-Maass, S., et al. Comparative pharmacology of human β-adrenergic receptor subtypes - characterization of stably transfected receptors in CHO cells Naunyn-Schmiedeberg's Arch. Pharmacol. 369(2), 151-159 (2004).

3. Ahles, A., and Englehardt, S. Polymorphic variants of adrenoceptors: Pharmacology, physiology, and role in disease Pharmacol. Rev. 66(3), 598-637 (2014).

4. Werner-Busse, A., Zuberbier, T., and Worm, M. The allergic emergency--management of severe allergic reactions J.Dtsch.Dermatol.Ges. 12(5), 379-387 (2014).

5. Chen, S.q. Advances in clinical studies of cardiopulmonary resuscitation World J.Emerg.Med. 6(2), 85-93 (2015).

6. Wilkins, T., Khan, N., Nabh, A., et al. Diagnosis and management of upper gastrointestinal bleeding American Family Physician 85(5), 469-476 (2012).

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