Pricing updated 2019-05-26. Prices are subject to change without notice.
(-)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for α1A-, β2-, and β1-adrenergic receptors, respectively).1,2,3 Through these receptors, (-)-epinephrine may induce either contraction or relaxation of vascular smooth muscle, depending on adrenoceptor subtype expression.3 Receptor-mediated actions of (-)-epinephrine are also relevant to blocking anaphylaxis, reversing cardiac arrest, and reducing bleeding in clinical trials.4,5,6
Warning - this product is not for human or veterinary use.
View the Cayman Structure Database for chemical structure definitions for many Cayman products
Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.
Rothman, R.B., Vu, N., Partilla, J.S., et al. In vitro characterization of ephedrine-
Hoffmann, C., Leitz, M.R., Oberdorf-
3. Ahles, A., and Englehardt, S. Polymorphic variants of adrenoceptors: Pharmacology, physiology, and role in disease Pharmacol. Rev. 66(3), 598-637 (2014).
5. Chen, S.q. Advances in clinical studies of cardiopulmonary resuscitation World J.Emerg.Med. 6(2), 85-93 (2015).
6. Wilkins, T., Khan, N., Nabh, A., et al. Diagnosis and management of upper gastrointestinal bleeding American Family Physician 85(5), 469-476 (2012).