Anthrax Edema Factor Assay Kit

Item № 18918
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL $0.00
96 wells $1,044.00 0.00

Pricing updated 2018-02-19. Prices are subject to change without notice.

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Description
Features
  • Measures Cyclic AMP, the conversion product of cytosolic adenosine triphosphate catalyzed by the edema factor complex of Anthrax
  • Edema factor included as quality control
  • Assay validated in human plasma samples

Anthrax is an infectious disease caused by Bacillus anthracis. The bacterium’s pathogenicity results when a tripartite protein toxin is secreted into a host system causing tissue swelling and apoptosis. This toxin is a mixture of three protein components: protective antigen (PA), edema factor (EF), and lethal factor (LF). EF is a calmodulin and Ca2+-dependent adenylyl cyclase that catalyzes the conversion of cytosolic adenosine triphosphate (ATP) into cyclic adenosine monophosphate (cAMP). This assay uses the natural capacity of EF to convert ATP into cAMP. Standards or samples containing EF are incubated with calmodulin and ATP, which is converted to cAMP. After oxidation and derivatization, cAMP is monitored by competitive immunoassay. [Bertin Catalog No. A05230]

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
Limit of Detection
0.647 pg/ml
Assay Range
1,000-7.81 pg/ml

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
Product Downloads

Download Kit Booklet

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

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You may be eligible to receive a free sample of Anthrax Edema Factor Assay Kit under the Cayman Challenge program.

Cayman Chemical

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Ann Arbor, Michigan 48108 USA

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