Anthrax Edema Factor Assay Kit | Cayman Chemical
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Anthrax Edema Factor Assay Kit

Item № 18918
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     96 wells $1,044.00 0.00

Pricing updated 2018-11-16. Prices are subject to change without notice.

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  • Measures Cyclic AMP, the conversion product of cytosolic adenosine triphosphate catalyzed by the edema factor complex of Anthrax
  • Edema factor included as quality control
  • Assay validated in human plasma samples

Anthrax is an infectious disease caused by Bacillus anthracis. The bacterium’s pathogenicity results when a tripartite protein toxin is secreted into a host system causing tissue swelling and apoptosis. This toxin is a mixture of three protein components: protective antigen (PA), edema factor (EF), and lethal factor (LF). EF is a calmodulin and Ca2+-dependent adenylyl cyclase that catalyzes the conversion of cytosolic adenosine triphosphate (ATP) into cyclic adenosine monophosphate (cAMP). This assay uses the natural capacity of EF to convert ATP into cAMP. Standards or samples containing EF are incubated with calmodulin and ATP, which is converted to cAMP. After oxidation and derivatization, cAMP is monitored by competitive immunoassay. [Bertin Catalog No. A05230]

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
Limit of Detection
0.647 pg/ml
Assay Range
1,000-7.81 pg/ml

Warning - this product is not for human or veterinary use.

Shipping & Storage
Wet ice in continental US; may vary elsewhere
≥ 1 year
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Additional Information

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