Pricing updated 2018-08-17. Prices are subject to change without notice.
Syringic acid is a naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol.1 It is also a component of phenolic extracts from various plants that have antioxidant and prooxidant activities.2 Syringic acid has been shown to inhibit aldose reductase (IC50 = 213 µg/ml), proteasome activity, and cancer cell proliferation.3,4 Phenolic extracts containing syringic acid have been shown to inhibit α-amylase and α-glucosidase activities and reduce lipid peroxidation in vitro.5
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Hara, H., Masai, E., Katayama, Y., et al. The 4-
2. Cotoras, M., Vivanco, H., Melo, R., et al. In vitro and in vivo evaluation of the antioxidant and prooxidant activity of phenolic compounds obtained from grape (Vitis vinifera) pomace. Molecules 19(12), 21154-21167 (2014).
3. Wei, X., Chen, D., Yi, Y., et al. Syringic acid extracted from Herba dendrobii prevents diabetic cataract pathogenesis by inhibiting aldose reductase activity. Evidence-Based Complementary and alternative Medicine 2012:426537, (2012).
Orabi, K.Y., Abazar, M.S., El Sayed, K.A., et al. Selective growth inhibition of human malignant melanoma cells by syringic acid-
5. Oboh, G., Isaac, A.T., Akinyemi, A.J., et al. Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside induced lipid peroxidation in rats' pancreas by phenolic extracts of avocado pear leaves and fruit. Int.J.Biomed.Sci. 10(3), 208-216 (2014).