We collect cookies for vital website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.

Syringic Acid

Item № 19196
CAS № 530-57-4
Purity ≥98%
product image
                (CAS 530-57-4)
     10 g $25.00 0.00
     25 g $47.00 0.00
     50 g $69.00 0.00
     100 g $108.00 0.00

Pricing updated 2019-06-15. Prices are subject to change without notice.

  • 3,5-dimethyl ether Gallic Acid
  • 3,5-dimethoxy-4-hydroxy Benzoic Acid
  • NSC 2129

Syringic acid is a naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol.1 It is also a component of phenolic extracts from various plants that have antioxidant and prooxidant activities.2 Syringic acid has been shown to inhibit aldose reductase (IC50 = 213 µg/ml), proteasome activity, and cancer cell proliferation.3,4 Phenolic extracts containing syringic acid have been shown to inhibit α-amylase and α-glucosidase activities and reduce lipid peroxidation in vitro.5

Recommended Products

Related Products
View Related Product Categories
Technical Information
Formal Name
4-hydroxy-3,5-dimethoxy-benzoic acid
CAS Number
  • 3,5-dimethyl ether Gallic Acid
  • 3,5-dimethoxy-4-hydroxy Benzoic Acid
  • NSC 2129
Molecular Formula
Formula Weight
A crystalline solid
218, 274 nm
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 2 years
Downloads & Resources
Product Downloads

Download Product Insert

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Hara, H., Masai, E., Katayama, Y., et al. The 4-oxalomesaconate hydratase gene, involved in the protocatechuate 4,5-cleavage pathway, is essential to vanillate and syringate degradation in Sphingomonas paucimobilis SYK-6 Journal of Bacteriology 182(24), 6950-6957 (2000).

2. Cotoras, M., Vivanco, H., Melo, R., et al. In vitro and in vivo evaluation of the antioxidant and prooxidant activity of phenolic compounds obtained from grape (Vitis vinifera) pomace Molecules 19(12), 21154-21167 (2014).

3. Wei, X., Chen, D., Yi, Y., et al. Syringic acid extracted from Herba dendrobii prevents diabetic cataract pathogenesis by inhibiting aldose reductase activity Evidence-Based Complementary and alternative Medicine 2012:426537, (2012).

4. Orabi, K.Y., Abazar, M.S., El Sayed, K.A., et al. Selective growth inhibition of human malignant melanoma cells by syringic acid-derived proteasome inhibitors Cancer Cell Int. 13(1), (2013).

5. Oboh, G., Isaac, A.T., Akinyemi, A.J., et al. Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside induced lipid peroxidation in rats' pancreas by phenolic extracts of avocado pear leaves and fruit Int.J.Biomed.Sci. 10(3), 208-216 (2014).

Technical Support
Contact Us
  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Cayman Contract Services

We work with scientists to accelerate their research, drug discovery, and drug development needs through our expertise in the following areas:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640