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Icaritin

Item № 20236
CAS № 118525-40-9
Purity ≥98%
product image
                (CAS 118525-40-9)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     500 µg $25.00 0.00
     1 mg $38.00 0.00
     5 mg $80.00 0.00

Pricing updated 2019-07-23. Prices are subject to change without notice.

Description

Icaritin is a flavonoid first isolated from the Chinese herb H. epimedii that demonstrates anticancer activity against a variety of tumor cell lines.1 It has been shown to inhibit fatty acid synthase, reducing IGF-1-induced activation of STAT3 in several melanoma cell lines.1

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Technical Information
Formal Name
3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
CAS Number
118525-40-9
Molecular Formula
C21H20O6
Formula Weight
368.4
Purity
≥98%
Formulation
A crystalline solid
λmax
273, 318, 374 nm
SMILES
C/C(C)=C\CC1=C2C(C(C(O)=C(C3=CC=C(OC)C=C3)O2)=O)=C(O)C=C1O
InChI Code
InChI=1S/C21H20O6/c1-11(2)4-9-14-15(22)10-16(23)17-18(24)19(25)20(27-21(14)17)12-5-7-13(26-3)8-6-12/h4-8,10,22-23,25H,9H2,1-3H3
InChI Key
TUUXBSASAQJECY-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
Downloads & Resources
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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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References & Product Citations
Product Description References

1. Wu, J., Du, J., Fu, X., et al. Iciartin, a novel FASN inhibitor, exerts anti-melanoma activities through IGF-1R/STAT3 signaling Oncotarget (2016).

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