Pricing updated 2019-07-17. Prices are subject to change without notice.
3',4',7-Trihydroxyisoflavone is a natural isoflavonoid that has antioxidant activity.1 It can be produced by the metabolism of daidzein (Item No. 10005166) or daidzin (Item No. 13202).2,3 3',4',7-Trihydroxyisoflavone inhibits several signaling pathways in cells, including tyrosinase-mediated melanin formation (IC50 = 5.2 µM), casein kinase II-mediated phosphorylation of 60S acidic ribosomal P proteins, and cyclin-dependent, kinase-regulated cell proliferation.4,5,6
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1. Komiyama, K., Funayama, S., Anraku, Y., et al. Isolation of isoflavonoids possessing antioxidant activity from the fermentation broth of Streptomyces sp J. Antibiot. (Tokyo) 42(9), 1344-1349 (1989).
3. Yasuda, T., and Ohsawa, K. Urinary metabolites of daidzin orally administered in rats Biol. Pharm. Bull. 21(9), 953-957 (1998).
Maekawa, T., Kosuge, S., Sakamoto, S., et al. Biochemical characterization of 60S acidic ribosomal P proteins associated with CK-
Lee, D.E., Lee, K.Q., Song, N.R., et al. 7,3',4'-