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Item № 22478
CAS № 246529-22-6
Purity ≥95%
product image
                (CAS 246529-22-6)
     1 mg $35.00 0.00
     5 mg $158.00 0.00
     10 mg $280.00 0.00
     25 mg $569.00 0.00

Pricing updated 2019-07-17. Prices are subject to change without notice.

  • Arachidyl Amido Cholanoic Acid

Aramchol, also known as arachidyl amido cholanoic acid, is a conjugate of arachidic acid (Item No. 9000339) and cholic acid (Item No. 20250).1 It reduces ex vivo cholesterol crystallization in native human bile and dissolves pre-formed cholesterol crystals in a dose-dependent manner. In vivo, aramchol completely prevents the formation of cholesterol crystals and gallstones in mice fed a lithogenic, high-fat diet. It also prevents lithogenic, high-fat diet-induced fatty liver in mice, rats, and hamsters.2 Formulations containing aramchol have been investigated clinically for the treatment of non-alcoholic fatty liver disease (NAFLD).3

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Technical Information
Formal Name
(3β,5β,7α,12α)-7,12-dihydroxy-3-[(1-oxoeicosyl)amino]-cholan-24-oic acid
CAS Number
  • Arachidyl Amido Cholanoic Acid
Molecular Formula
Formula Weight
A crystalline solid
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Gilat, T., Leikin-Frenkel, A., Goldiner, I., et al. Arachidyl amido cholanoic acid (Aramchol) is a cholesterol solubilizer and prevents the formation of cholesterol gallstones in inbred mice Lipids 36(10), 1135-1140 (2001).

2. Gilat, T., Leikin-Frenkel, A., Goldiner, I., et al. Prevention of diet-induced fatty liver in experimental animals by the oral administration of a fatty acid bile acid conjugate (FABAC) Hepatology 38(2), 436-442 (2003).

3. Safadi, R., Konikoff, F.M., Mahamid, M., et al. The fatty acid-bile acid conjugate Aramchol reduces liver fat content in patients with nonalcoholic fatty liver disease Clin. Gastroenterol. Hepatol. 12(12), 2085-2091 (2014).

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