TNF-α (pig) ELISA Kit | Cayman Chemical
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TNF-α (pig) ELISA Kit

Item № 23616
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     96 wells $450.00 0.00

Pricing updated 2018-09-23. Prices are subject to change without notice.

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Description
Features
  • Developed specifically for measuring TNF-α levels in porcine samples
  • Measure TNF-α levels down to 0.02 ng/ml
Synonyms
  • Cachectin
  • Tumor Necrosis Factor-α EIA Kit

Known as cachectin, the TNF-α is a glycoprotein of 156 amino acids produced from a precursor processed by action of a metalloprotease. Isolated for the first time in 1975 by Carswell, it’s a cytokine of the innate immunity. Interleukin-1 or bacterial endotoxins stimulate the production of TNF-α by immune cells (activated macrophages, NK cells, and monocytes) and non-immune cells (keratinocytes, vascular smooth muscle cells, and granulosa lutein cells). The main function of the TNF-α is to act as an immunomodulator and as a mediator of inflammatory responses in the phenomena of host resistance to infection. It allows neutrophils and macrophages recruitment to infectious sites by stimulating the production of adhesion molecules and chemokines (chemotactic cytokines) by endothelial cells. TNF-α also acts on the hypothalamus to trigger the fever. Over-production of TNF-α has been implicated in a number of pathological conditions including cachexia, septic shock, and autoimmune disorders. [Bertin Catalog No. A05411]

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
Synonyms
  • Cachectin
  • Tumor Necrosis Factor-α EIA Kit
Limit of Detection
≤0.02 ng/ml
Assay Range
0.02-20,00 ng/ml
Cross Reactivity
  • (+) Recombinant TNF-α (feline)
  • (+) Recombinant TNF-α (bovine)
  • (+) Recombinant TNF-α (dolphin)
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Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
4°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 6 months
Downloads & Resources
Product Downloads

Download Kit Booklet

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

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