CGMP Travoprost

Item № 30011
CAS № 157283-68-6
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                (CAS 157283-68-6)
Description
Alternative Names
  • (+)-Fluprostenol isopropyl ester
  • (+)-16-m-trifluoromethylphenoxy tetranor Prostaglandin F isopropyl ester

Travoprost is a potent FP receptor agonist that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. The DMF for Travoprost is on file with the US FDA, Canada, India, China, in several EU member states, and in several other countries.

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Technical Information
Formal Name
(+)-9α,11α,15R-trihydroxy-16-(3-(trifluoromethyl)phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester
CAS Number
157283-68-6
Alternative Names
  • (+)-Fluprostenol isopropyl ester
  • (+)-16-m-trifluoromethylphenoxy tetranor Prostaglandin F isopropyl ester
Molecular Formula
C26H35F3O6
Formula Weight
500.6
SMILES
CC(C)OC(CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2)[C@H](O)C[C@@H]1O)=O
InChI Code
InChI=1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t19-,21-,22-,23+,24-/m1/s1
InChI Key
MKPLKVHSHYCHOC-AHTXBMBWSA-N
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