An mRNA for the expression of mOrange
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mOrange mRNA (Cap-1; m1Ψ)

Item No. 43680

Product Insert (PDF)
Technical Information
Synonyms
  • mOrange mRNA (Cap-1; N1-Methylpseudouridine)
Emission
562 nm
Excitation
548 nm
Formulation
1 mM Sodium Citrate, pH 6.4
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    Product Description

    mOrange mRNA (Cap-1; m1Ψ) encodes mOrange, an orange fluorescent protein and derivative of Discosoma red fluorescent protein (DsRed) that displays excitation and emission maxima to 548 and 562 nm, respectively.1 It is capped using a co-transcriptional capping method, resulting in the naturally occurring Cap-1 structure with high capping efficiency. mOrange mRNA is also polyadenylated and modified with N1-methylpseudouridine (m1Ψ) to reduce the host cell immune response and enhance mRNA stability. Encapsulation of mOrange mRNA (Cap-1; m1ψ) in lipid nanoparticles (LNPs) can be used for mRNA delivery and expression of mOrange.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Shaner, N.C., Campbell, R.E., Steinbach, P.A., et alImproved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat. Biotechnol. 22(12), 1567-1572 (2004).