PAD4 Autoantibody ELISA Kit | Cayman Chemical
We collect cookies for vital website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.

PAD4 Autoantibody ELISA Kit

Item № 500930
product image
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     96 wells $425.00 0.00

Pricing updated 2018-11-19. Prices are subject to change without notice.

Description
Features
  • Measure anti-PAD4 autoantibodies of any isotype (IgM, IgG, IgA)
  • For use in human plasma and serum (no need to purify samples)
  • Assay range: 15.6-1,000 U/ml with an LLOQ of 31.3 U/ml
Synonyms
  • PAD4 Autoantibody EIA Kit
  • PADI4
  • PADI5
  • PDI5
  • Peptidylartginine Deaminase 4
  • Protein Arginine Deiminase 4

Protein arginine deiminase 4 (PAD4) is a guanidino-modifying enzyme which catalyzes the conversion of specific arginine residues to citrulline in a calcium-dependent manner. PAD4 activity is increased in rheumatoid arthritis (RA), producing citrulline-containing proteins (CCP) that induce the formation of arthritogenic autoantibodies. In addition to anti-CCP autoantibodies, 23-45% of RA patients also produce autoantibodies specific for the PAD4 enzyme itself. Cayman’s PAD4 Autoantibody ELISA Kit is an immunometric assay which can be used to measure anti-PAD4 autoantibodies of any isotype (IgM, IgG, and IgA) in human plasma and serum without prior sample purification. Affinity-purified anti-PAD4 antibody isolated from the plasma of a patient with RA is used as the standard. One unit is approximately equal to 1 ng of anti-PAD4 Ig protein. The standard curve spans the range of 15.6-1,000 U/ml, with an LLOQ of 31.3 U/ml.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

Recommended Products

Related Products
View Related Product Categories
Technical Information
Synonyms
  • PAD4 Autoantibody EIA Kit
  • PADI4
  • PADI5
  • PDI5
  • Peptidylartginine Deaminase 4
  • Protein Arginine Deiminase 4
Assay Range
15.6-1,000 U/ml
Lower Limit of Quantification
31.3 U/ml

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
4°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
Product Downloads

Download Kit Booklet

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

Technical Support
Contact Us
  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Cayman Contract Services

We work with scientists to accelerate their research, drug discovery, and drug development needs through our expertise in the following areas:

Promotions

View all of our current Promotions

You may be eligible to receive a free sample of PAD4 Autoantibody ELISA Kit under the Cayman Challenge program.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640