Anti-Citrullinated Human Fibrinogen Assay Kit (mouse) | Cayman Chemical

Anti-Citrullinated Human Fibrinogen Assay Kit (mouse)

Item № 501270
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     96 wells $575.00 0.00

Pricing updated 2018-05-20. Prices are subject to change without notice.

Description
Features
  • Measure antibodies specific for citrullinated human fibrinogen
  • Use with mouse plasma or serum
  • Assay Range: 0.15-10 μg/ml with an LLOQ of 0.15 μg/ml
  • Human fibrinogen affinity sorbent included for removal of any antibodies capable of reacting with non-citrullinated (unmodified) fibrinogen prior to analysis

Immunization of mice with citrullinated human fibrinogen, especially mice expressing the human HLA-DR4 transgene, induces an arthritic response driven by the production of antibodies that recognize citrullinated epitopes. The polyclonal antibody response produces antibodies reactive with both citrullinated human fibrinogen and unmodified, noncitrullinated human fibrinogen. Cayman’s Anti-Citrullinated Human Fibrinogen Assay (mouse) is an immunometric (sandwich) assay that can be used to distinguish the antibody response to citrullinated human fibrinogen from the antibody response to unmodified human fibrinogen in mouse serum or plasma. A human fibrinogen affinity sorbent is provided with the kit so that any antibodies capable of reacting with non-citrullinated (unmodified) fibrinogen can be removed prior to analysis of the remaining anti-citrullinated fibrinogen antibodies for an accurate analysis of the anti-citrulline response. This kit uses a citrullinated human fibrinogen-coated plate and a detection antibody recognizing mouse IgG. An anti-citrullinated human fibrinogen monoclonal antibody is included as a standard. The standard curve spans the range of 0.15 to 10 µg/ml, with an an LLOQ of 0.15 µg/ml.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
Assay Range
0.15-10 µg/ml
Lower Limit of Quantification
0.15 µg/ml

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
4°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 6 months
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Download Kit Booklet

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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

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You may be eligible to receive a free sample of Anti-Citrullinated Human Fibrinogen Assay Kit (mouse) under the Cayman Challenge program.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640