|96 solid wells||$245.00||0.00|
|96 strip wells||$245.00||0.00|
Pricing updated 2019-03-26. Prices are subject to change without notice.
Pregnanediol-3-Glucuronide (5β-pregnane-3α,20α-diol-3α-glucuronide, PDG or P3G) is the major metabolite of progesterone, an endogenous steroid and the most important member of the class of steroid hormones known as progestogens. Progesterone is important in a variety of biological functions such as preparing the endometrium for implantation, maintaining pregnancy, differentiating breast tissue, and promoting normal development of neurons in the brain as a neuro steroid. Low progesterone levels are linked to chronic anovulation which is reported to be associated with female infertility, breast cancer and endometrial cancer.1,2 Levels of PDG in the urine correlate highly to levels of progesterone measured in the serum.3,4 PDG analysis may be used as a non-invasive method to indirectly measure progesterone and therefore might be used as a biomarker for luteal activity, ovarian cancer, and a variety of other biological disorders.5,6,7
Warning - this product is not for human or veterinary use.
View the Cayman Structure Database for chemical structure definitions for many Cayman products
Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.
Kassam, A., Overstreet, J.W., Snow-
2. Wiebe, J.P. Progesterone metabolites in breast cancer Endocr. Relat. Cancer 13(3), 717-738 (2006).
O'Connor, K.A., Brindle, E., Holman, D.J., et al. Urinary estrone conjugate and pregnanediol 3-
4. Munro, C.J., Stabenfeldt, G.H., Cragun, J.R., et al. Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassay Clin. Chem. 37(6), 838-844 (1991).
Pavlovic, J.M., Allshouse, A.A., Santoro, N.F., et al. Sex hormones in women with and without migraine: Evidence of migraine-
6. Lukanova, A., and Kaaks, R. Endogenous hormones and ovarian cancer: Epidemiology and current hypotheses Can. Epidemiol Biomarkers Prev. 14(1), 98-107 (2005).
7. Kim, J.J., Kurita, T., and Bulun, S.E. Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer Endocr. Rev. 34(1), 130-162 (2013).