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11-Oxoetiocholanolone ELISA Kit

Item № 501420
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     96 solid wells $375.00 0.00
     96 strip wells $375.00 0.00

Pricing updated 2019-05-23. Prices are subject to change without notice.

Description
Features
  • Measure 11-oxoetiocholanolone in ungulate feces and human urine
  • Simple extraction procedures for rapid sample analysis
  • Assay 24 samples in triplicate or 36 samples in duplicate
  • Measure 11-oxoetiocholanolone levels down to 0.2 ng/ml
Synonyms
  • 11-Oxo
  • 11-Oxoetiocholanolone EIA Kit

11-Oxoetiocholanolone is a metabolite of cortisol that is found in the feces of ungulates and other animals. Stress-induced glucocorticoids (cortisol, corticosterone) traditionally have been measured through blood sampling, but the collection process is known to cause stress in animals, interfering with experimental results.1 Fecal sample analysis provides more accurate detection of stress hormones, and it can be used to measure stress in both laboratory and free-ranging animals.1 11-Oxoetiocholanolone is also found in human urine. Increased levels of urinary 11-oxoetiocholanolone have been observed in the latter part of pregnancy and in patients with uterine leiomyomas.2,3 A study of postmenopausal women determined that 11-oxoetiocholanolone was indicative of stress-induced urinary incontinence.4

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
Synonyms
  • 11-Oxo
  • 11-Oxoetiocholanolone EIA Kit
Limit of Detection
0.11 ng/ml
Assay Range
0.061-1,000 ng/ml
Sensitivity
0.2 ng/ml
Mid-point
1.9 ng/ml
Origin
  • Animal/Bovine
  • Animal/Rabbit

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
Product Downloads

Download Kit Booklet

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Chelini, M.O.M., Otta, E., Yamakita, C., et al. Sex differences in the excretion of fecal glucocorticoid metabolites in the Syrian hamster J. Comp. Physiol. B 180, 919-925 (2010).

2. Birke, G., Gemzell, C.A., Plantin, L.O., et al. Plasma levels of 17-hydroxycorticosteroids and urinary excretion pattern of keto-steroids in normal pregnancy Acta Endocrinologica 27, 389-402 (1958).

3. Jung, B.H., Bai, S.W., and Chung, B.C. Endogenous urinary steroids in premenopausal women with uterine leiomyomas Int. J. Gynaecol. Obstet. 84(1), 55-60 (2004).

4. Bai, S.W., Jung, B.H., Chung, B.C., et al. Relationship between urinary profile of the endogenous steroids and postmenopausal women with stress urinary incontinence Neurourology and Urodynamics 22, 198-205 (2003).

Technical Support
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