2-Methoxyestradiol ELISA Kit | Cayman Chemical
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2-Methoxyestradiol ELISA Kit

Item № 582261
product image
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     96 solid wells $400.00 0.00
     96 strip wells $400.00 0.00
     480 solid wells $1,500.00 0.00
     480 strip wells $1,500.00 0.00

Pricing updated 2018-11-15. Prices are subject to change without notice.

Description
Features
  • Detect 2-ME2
  • Assay 24 samples in triplicate or 36 samples in duplicate
  • Measure 2-ME2 levels down to 40 pg/ml
  • Incubation: 18 hours | Development: 90-120 minutes | Read: Colorimetric at 405-420 nm
Synonyms
  • 2-Hydroxyestradiol 2-methyl ester
  • 2-ME2 EIA Kit

2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol produced by CYP450-dependant hydroxylation followed by catechol-O-methyltransferase-catalyzed O-methylation. Deficiency in catechol-O-methyltransferase is associated with pre-eclampsia. Therefore, 2-ME2 may be utilized as a plasma and urinary diagnostic marker for this disease, as well as a therapeutic supplement for its prevention. Several clinical trials have demonstrated the antitumor effects of 2-ME2 in prostate cancer, breast cancer, renal cell carcinoma, ovarian cancer, glioblastoma, and multiple myeloma. Other studies indicate that 2-ME2 exhibits more potent cardioprotective effects than estradiol. Cayman’s 2-Methoxyestradiol ELISA Kit is a competitive assay that can be used for quantification of 2-ME2 in plasma, urine, and other sample matrices.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
Synonyms
  • 2-Hydroxyestradiol 2-methyl ester
  • 2-ME2 EIA Kit
Assay Range
13.1-8,000 pg/ml
Sensitivity
80% B/B0: 40 pg/ml
Mid-point
50% B/B0: 330-390 pg/ml
Cross Reactivity
  • (17α-Estradiol) <0.01%
  • (Pregnenolone) <0.01%
  • (2-Methoxyestradiol) 100%
Show all 10

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
Product Downloads

Download Kit Booklet

Download Abbreviated Kit Protocol

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

Technical Support

All 480 well kits are supplied with a single 500 dtn vial of antiserum and tracer, or Fab' conjugate that must be used within the stated time following reconstitution.

Contact Us
  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
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You may be eligible to receive a free sample of 2-Methoxyestradiol ELISA Kit under the Cayman Challenge program.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640