Pricing updated 2019-06-15. Prices are subject to change without notice.
Cayman’s 7-AAD/CFSE Cell-Mediated Cytotoxicity Assay Kit employs CFSE to label target cells within the mixed cell population and 7-AAD to label dead cells. This kit provides an improvement over the traditional 51chromium (51Cr) release assay to assess cell-mediated cytotoxicity. CFSE labeling is more sensitive, does not employ radioisotopes, and cytolysis can be assessed at the single-cell level. The mixed lymphocyte reaction is a cornerstone method of immunology1, and this kit can help immunologists to detect subtle changes in cytotoxic lymphocyte function. The kit provides sufficient reagents to effectively stain approximately 109 cells.
Warning - this product is not for human or veterinary use.
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1. Benczur, M., Petrányi, G.G., Pálffy, G., et al. Dysfunction of natural killer cells in multiple sclerosis: A possible pathogenetic factor Clinical and Experimental Immunology 39, 657-662 (1980).
Guo, L., Yang, L., Speck, E.R., et al. Allogeneic platelet transfusions prevent murine T-