Pricing updated 2018-02-22. Prices are subject to change without notice.
Cayman's MitoCheck® Mito Stess Test (ACU format) is designed to measure oxygen consumption rate (OCR) and extracellular acidification (ECA) using MitoXpress® Xtra and pH-Xtra™, respectively. OCR and ECA measurements occur simultaneously, and in real time under tightly controlled atmospheric conditions using open-flow respirometry.1,2,3,4 Included in this kit are the control compounds oligomycin (Complex V inhibitor), FCCP (uncoupler, increases OCR), and antimycin A (inhibits OCR) for easy assessment of mitochondrial health. This assay has been designed to work exclusively with the BMG LABTECH CLARIOstar® microplate reader equipped with dual injection ports, TRF detection, and ACU.
Warning - this product is not for human or veterinary use.
View the Cayman Structure Database for chemical structure definitions for many Cayman products
Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.
1. Brookes, P.S.,Kraus, D.W.,Shiva, S., et al. Control of mitochondrial respiration by NO; Effects of low oxygen and respiratory state. The Journal of Biological Chemisty 278(34), 31603-31609 (2003).
2. Hoffman, D.L., and Brookes, P.S. Oxygen sensitivity of mitochondrial reactive oxygen species generation depends on metabolic conditions. The Journal of Biological Chemisty 284(24), 16236-16245 (2009).
Hoffman, D.L.,Salter, J.D., and Brookes, P.S. Response of mitochondrial reactive oxygen species generation to steady-