We collect cookies for vital website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.

THC Metabolite ELISA Kit

Item № 701570
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     96 solid wells $295.00 0.00
     96 strip wells $295.00 0.00

Pricing updated 2019-04-25. Prices are subject to change without notice.

Description
Features
  • Measures (−)-11-nor-9-carboxy-Δ9-THC in biological matrices
  • Assay 24 samples in triplicate or 36 samples in duplicate
  • Measure THC metabolite levels down to 0.037 ng/ml
  • Rapid 2-hour incubation time
Synonyms
  • Tetrahydrocannabinol Metabolite
  • THC Metabolite EIA Kit

Δ9-Tetrahydrocannabinol (Δ9THC) is the primary psychoactive chemical that results from the consumption of Cannabis. Upon consumption, this cannabinoid (CB) acts as a partial agonist with both the central CB receptor 1 (CB1) and the peripheral CB receptor 2 (CB2).1,2 Its actions are analogous to the endogenous neurotransmitter anandamide when it binds to receptors and alters mental and physical functions in the body.3

Once in the liver, Δ9-THC gets broken down by cytochrome p450 enzymes CYP2C9, CYP2C19, CYP3A4, to the psychoactive metabolite 11-hydroxy-THC.4,5 11-hydroxy-THC is then further oxidized to the non-psychoactive metabolite 11-nor-9-carboxy-THC.6 This carboxy form has been found to be the most abundant metabolite of Δ9-Tetrahydrocannabinol. For this reason, it is often used as the main urinary marker for Cannabis consumption.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

Recommended Products

Related Products
View Related Product Categories
Technical Information
Synonyms
  • Tetrahydrocannabinol Metabolite
  • THC Metabolite EIA Kit
Limit of Detection
0.37 ng/ml
Assay Range
0.017-5.0 ng/ml
Sensitivity
0.072 ng/ml
Mid-point
0.30 ng/ml
Origin
  • Animal/Bovine
  • Animal/Mouse

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
Product Downloads

Download Kit Booklet

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

ID Tools

View our Base Peak Identification Tool

View our Flipbook Identification Tool

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

View the Cayman Spectral Library (CSL) for ChemStation-searchable GC-MS spectra of many of Cayman's emerging forensic drug standards

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Viñals, X., Moreno, E., Lanfumey, L., et al. Cognitive impairment induced by delta9-tetrahydrocannabinol occurs through heteromers between cannabinoid CB1 and serotonin 5-HT2A receptors PLoS One 13(7), e1002194 (2015).

2. Pertwee, R.G., Howlett, A.C., Abood, M.E., et al. International union of basic and clinical pharmacology. LXXIX. Cannabinoid receptors and their ligands: Beyond CB1 and CB2 Pharmacol. Rev. 62(4), 588-631 (2010).

3. Pertwee, R.G. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-Tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin Br. J. Pharmacol. 153(2), 199-215 (2008).

4. Arellano, A.L., Papaseit, E., Romaguera, A., et al. Neuropsychiatric and general interactions of natural and synthetic cannabinoids with drugs of abuse and medicines CNS Neurol. Disord. Drug Target 16(5), 554-566 (2017).

5. Watanabe, K., Yamaori, S., Funahashi, T., et al. Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Life Sci. 80(15), 1415-1419 (2007).

6. Schwilke, E.W., Schwope, D.M., Karschner, E.L., et al. Δ9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC plasma pharmacokinetics during and after continuous high-dose oral THC Clin. Chem. 55(12), 2180-2189 (2009).

Technical Support
Contact Us
  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Cayman Contract Services

We work with scientists to accelerate their research, drug discovery, and drug development needs through our expertise in the following areas:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640