A PPARγ ligand that disrupts hormone-mediated cell differentiation
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BADGE

Item No. 70790

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2'-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bis-oxirane
CAS Number
1675-54-3
Synonyms
  • Bisphenol A diglycidyl ether
  • DGEBA
  • NSC 5022
Molecular Formula
C21H24O4
Formula Weight
340.4
Purity
≥85%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: MiscibleDMSO: MiscibleEthanol: Miscible
λmax
228, 277, 283 nm
SMILES
CC(C)(c1ccc(OCC2OC2)cc1)c1ccc(OCC2OC2)cc1
InChi Code
InChI=1S/C21H24O4/c1-21(2,15-3-7-17(8-4-15)22-11-19-13-24-19)16-5-9-18(10-6-16)23-12-20-14-25-20/h3-10,19-20H,11-14H2,1-2H3
InChi Key
LCFVJGUPQDGYKZ-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 g

    $19

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    50 g

    $32

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    100 g

    $53

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    500 g

    $161

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    Cayman Chemical
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    Product Description

    BADGE is a synthetic compound used in the production of polycarbonate and industrial plastics. This compound was recently identified as an antagonist of PPARγ.1 BADGE binds to PPARγ with an apparent Kd of 100 µM and interferes with the ability of 3T3-L1 and 3T3-F442A cells to undergo hormone-mediated cell differentiation.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wright, H.M., Clish, C.B., Mikami, T., et al. A synthetic antagonist for the peroxisome proliferator-activated receptor γ inhibits adipocyte differentiation. The Journal of Biological Chemisty 275(3), 1873-1877 (2000).