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(+)-Catechin (hydrate)

Item № 70940
CAS № 225937-10-0
Purity ≥98%
product image
                (CAS 225937-10-0)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 g $26.00 0.00
     5 g $59.00 0.00
     10 g $104.00 0.00
     25 g $228.00 0.00

Pricing updated 2019-04-24. Prices are subject to change without notice.

Description
Synonyms
  • D-(+)-Catechin
  • Catechuic Acid
  • Cyanidol

Catechin is a polyphenolic flavonoid which has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechin is a more potent antioxidant than ascorbate or α-tocopherol in certain in vitro assays of lipid peroxidation.1 Catechin inhibits the free radical-induced oxidation of isolated LDL by AAPH.2 It has also been reported to act as an inhibitor of COX-1 with an IC50 of about 80 µM.3 Catechin and other related procyanidin compounds have antitumor activity when tested in a two-stage mouse epidermal carcinoma model employing topical application.1

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Technical Information
Formal Name
2R-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3S,5,7-triol, hydrate
CAS Number
225937-10-0
Synonyms
  • D-(+)-Catechin
  • Catechuic Acid
  • Cyanidol
Molecular Formula
C15H14O6 • XH2O
Formula Weight
290.3
Purity
≥98%
Formulation
A crystalline solid
λmax
280 nm
SMILES
OC1=CC([C@@H](O2)[C@@H](O)CC3=C2C=C(O)C=C3O)=CC=C1O.O
InChI Code
InChI=1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1
InChI Key
OFUMQWOJBVNKLR-NQQJLSKUSA-N
Origin
  • Plant/Tea leaves

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
Downloads & Resources
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Additional Information

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References & Product Citations
Product Description References

1. Zhao, J., Wang, J., Chen, Y., et al. Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent Carcinogenesis 20, 1737-1745 (1999).

2. Frémont, L., Belguendouz, L., and Delpal, S. Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids Life Sciences 64, 2511-2521 (1999).

3. Noreen, Y., Serrano, G., and Perera, P. Flavan-3-ols isolated from some medicinal plants inhibiting COX-1 and COX-2 catalyzed prostaglandin biosynthesis Planta Medica 64, 520-524 (1998).

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