cis-Parinaric Acid (CAS 18427-44-6) | Cayman Chemical
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cis-Parinaric Acid

Item № 71430
CAS № 18427-44-6
Purity >95%
product image
                (CAS 18427-44-6)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     500 µg $99.00 0.00
     1 mg $188.00 0.00
     5 mg $792.00 0.00

Pricing updated 2018-12-19. Prices are subject to change without notice.

Description
Synonyms
  • α-Parinaric Acid

cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene. This chromophore provides for a natural fluorescence at 432 nm with an excitation wavelength at 320 nm. cis-Parinaric acid occurs naturally in the seeds of the Makita tree, a tropical rainforest tree indigenous to Fiji. Makita seeds are inedible, and this toxicity may be due at least in part to the unstable conjugated fatty acids, including cis-parinaric acid, contained within the seed. cis-Parinaric acid has been used for the measurement of phospholipase activity, lipase activity, and as an indicator of lipid peroxidation.1,2,3,4

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Technical Information
Formal Name
9Z,11E,13E,15Z-octadecatetraenoic acid
CAS Number
18427-44-6
Synonyms
  • α-Parinaric Acid
Molecular Formula
C18H28O2
Formula Weight
276.4
Purity
>95%
Formulation
A crystalline solid
λmax
292, 305, 319 nm
SMILES
CC/C=C\C=C/C=C\C=C\CCCCCCCC(=O)O
InChI Code
InChI=1S/C18H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-10H,2,11-17H2,1H3,(H,19,20)/b4-3-,6-5+,8-7+,10-9-
InChI Key
IJTNSXPMYKJZPR-ZSCYQOFPSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Wolf, C., Sagaert, L., and Bereziat, G. A sensitive assay of phospholipase using the fluorescent probe 2-parinaroyllecithin Biochemical and Biophysical Research Communications 99, 275-283 (1981).

2. Beisson, F., Ferté, N., Nari, J., et al. Use of naturally fluorescent triacylglycerols from Parinari glaberrimum to detect low lipase activities from Arabidopsis thaliana seedlings Journal of Lipid Research 40, 2313-2321 (1999).

3. McGuire, S.O., James-Kracke, M.R., Sun, G.Y., et al. An esterification protocol for cis-parinaric acid-determined lipid peroxidation in immune cells Lipids 32, 219-226 (1997).

4. de Hingh, Y.C.M., Meyer, J., Fischer, J.C., et al. Direct measurement of lipid peroxidation in submitochondrial particles Biochemistry 34, 12755-12760 (1995).

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