Pricing updated 2019-03-21. Prices are subject to change without notice.
Peroxynitrite is formed in vivo by the reaction of NO with superoxide.1,2,3 It is a powerful oxidizing agent that can initiate lipid peroxidation, oxidize sulfhydryls, and nitrate the aromatic residues of proteins.
Warning - this product is not for human or veterinary use.
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1. Pryor, W.A., and Squadrito, G.L. The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide American Journal of Physiology 268, L699-L722 (1995).
2. Beckman, J.S., and Koppenol, W.H. Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and the ugly Am. J. Physiol. 271(5 Pt 1), C1424-C1437 (1996).
3. Koppenol, W.H., Moreno, J.J., Pryor, W.A., et al. Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide Chemical Research in Toxicology 5, 834-842 (1992).
Donohue, E., Balgi, A.D., Komatsu, M., et al. Induction of covalently crosslinked p62 oligomers with reduced binding to polyubiquitinated proteins by the autophagy inhibitor verteporfin PLoS One 9(12), 1-30 (2014).