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Docosanoic Acid

Item № 9000338
CAS № 112-85-6
Purity ≥98%
product image
                (CAS 112-85-6)
     500 mg $16.00 0.00
     1 g $27.00 0.00
     5 g $48.00 0.00

Pricing updated 2019-07-17. Prices are subject to change without notice.

  • Behenic Acid
  • C22:0
  • DCA
  • NSC 32364

Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.1,2 It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).3 Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.4 Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.5 Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.

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Technical Information
CAS Number
  • Behenic Acid
  • C22:0
  • DCA
  • NSC 32364
Molecular Formula
Formula Weight
A crystalline solid
InChI Code
InChI Key
Side Chain Carbon Sum

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Dean, L.L., and Sanders, T.H. Hexacosanoic acid and other very long-chain fatty acids in peanut seed oil Plant Genet. Resour. 7(3), 252-256 (2009).

2. Sánchez-Machado, D.I., López-Cervantes, J., Núñez-Gastélum, J.A., et al. Effect of the refining process on Moringa oleifera seed oil quality Food Chem. 187, 53-57 (2015).

3. Iijima, H., Kasai, N., Chiku, H., et al. The inhibitory action of long-chain fatty acids on the DNA binding activity of p53 Lipids 41(6), 521-527 (2006).

4. Yonezawa, Y., Hada, T., Uryu, K., et al. Inhibitory action of C22-fatty acids on DNA polymerases and DNA topoisomerases Int. J. Mol. Med. 18(4), 583-588 (2006).

5. Serviddio, G., Bellanti, F., Villani, R., et al. Effects of dietary fatty acids and cholesterol excess on liver injury: A lipidomic approach Redox Biol. 9, 296-305 (2016).

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