Pricing updated 2019-07-17. Prices are subject to change without notice.
Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.1,2 It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).3 Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.4 Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.5 Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.
Warning - this product is not for human or veterinary use.
View the Cayman Structure Database for chemical structure definitions for many Cayman products
Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.
Dean, L.L., and Sanders, T.H. Hexacosanoic acid and other very long-
Iijima, H., Kasai, N., Chiku, H., et al. The inhibitory action of long-
Yonezawa, Y., Hada, T., Uryu, K., et al. Inhibitory action of C22-
5. Serviddio, G., Bellanti, F., Villani, R., et al. Effects of dietary fatty acids and cholesterol excess on liver injury: A lipidomic approach Redox Biol. 9, 296-305 (2016).