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Arachidonic Acid

Item № 90010
CAS № 506-32-1
Purity ≥98%
product image
                (CAS 506-32-1)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     50 mg $22.00 0.00
     100 mg $42.00 0.00
     250 mg $99.00 0.00
     500 mg $176.00 0.00

Pricing updated 2019-07-23. Prices are subject to change without notice.

Description
Synonyms
  • AA

Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways.1 Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.2

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Technical Information
Formal Name
5Z,8Z,11Z,14Z-eicosatetraenoic acid
CAS Number
506-32-1
Synonyms
  • AA
Molecular Formula
C20H32O2
Formula Weight
304.5
Purity
≥98%
Formulation
A solution in ethanol
SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O
InChI Code
InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-
InChI Key
YZXBAPSDXZZRGB-DOFZRALJSA-N
Side Chain Carbon Sum
20:4

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
Downloads & Resources
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Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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References & Product Citations
Product Description References

1. Nixon, A.B., Greene, D.G., and Wykle, R.L. Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophils Biochim. Biophys. Acta. 1300(3), 187-196 (1996).

2. Burgoyne, R.D., and Morgan, A. The control of free arachidonic acid levels Trends Biochem. Sci. 15(10), 365-366 (1990).

Product Citations

Magtanong, L., Ko, P.-J., To, M., et al. Exogenous monounsaturated fatty acids promote a ferroptosis-resistant cell state Cell Chem. Biol. 26(3), 420-432 (2019).

Sorgi, C.A., Peti, A.P.F., Petta, T., et al. Comprehensive high-resolution multiple-reaction monitoring mass spectrometry for targeted eicosanoid assays Sci. Data 5:180167, (2018).

Anthonymuthu, T.S., Kenny, E.M., Shrivastava, I., et al. Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE J. Am. Chem. Soc. 140(51), 17835-17839 (2018).

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