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Item № 90080
CAS № 13956-29-1
Purity ≥98%

Formulation:  A crystalline solid

     5 mg $49.00 0.00
     10 mg $88.00 0.00
     50 mg $270.00 0.00

Pricing updated 2019-07-21. Prices are subject to change without notice.

  • This product has been manufactured and tested to meet ISO/IEC 17025:2005 and ISO Guide 34:2009 guidelines
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for academic research at qualified institutions; please contact our sales department for pricing
  • CBD

Cannabidiol is an active phytocannabinoid identified in Cannabis (composes ~40% of the plant's extract). Unlike Δ9-THC (Item No. 12068), cannabidiol is considered to be non-psychoactive.1 Cannabidiol has a very low affinity for CB1 and CB2 receptors but acts as an indirect antagonist and is thought to potentiate the effects of Δ9-THC.2 Cannabidiol is reported to act as an CB2 receptor inverse agonist, GPR55 antagonist, and a 5-HT1A receptor agonist.2,3,4,5 It can allosterically modulate μ and δ-opioid receptors as well as agonize PPARγ receptors and stimulate intracellular calcium release.6,7

This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO Guide 34 guidelines. These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. All traceable RMs may be distinguished by their CofAs and can be downloaded below using the batch number located on the product label. For a representative CofA please contact our technical support.

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RMs and CRMs produced to accreditation standards: ISO/IEC 17025:2017 · ISO 17034:2016
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Technical Information
Formal Name
CAS Number
  • CBD
Molecular Formula
Formula Weight
A crystalline solid
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 1 year
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Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Kozela, E., Juknat, A., Kaushansky, N., et al. Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells J.Neuroinflamm. 12(52), (2015).

2. Mechoulam, R., Peters, M., Murillo-Rodriguez, E., et al. Cannabidiol - Recent advances Chemistry & Biodiversity 4, 1678-1692 (2007).

3. Pertwee, R.G. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-Tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin Br. J. Pharmacol. 153(2), 199-215 (2008).

4. Ryberg, E., Larsson, N., Sjögren, S., et al. The orphan receptor GPR55 is a novel cannabinoid receptor British Journal of Pharmacology 152, 1092-1101 (2007).

5. Russo, E.B., Burnett, A., Hall, B., et al. Agonistic properties of cannabidiol at 5-HT1a receptors Neurochemical Research 30(8), 1037-1043 (2005).

6. Campos, A.C., Moreira, F.A., Gomes, F.V., et al. Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders Phil.Trans.R.Soc.B. 367, 3364-3378 (2012).

7. Kathmann, M., Flau, K., Redmer, A., et al. Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors Naunyn-Schmiedeberg's Arch.Pharmacol. 372(5), 354-361 (2006).

Product Citations

Thapa, D., Cairns, E.A., Szczesniak, A.-M., et al. The cannabinoids D8THC, CBD, and HU-308 act via distinct receptors to reduce corneal pain and inflammation Cannabis and Cannabinoid Res. 3.1, (2018).

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