Cannabidiol (exempt preparation) (CAS 13956-29-1) | Cayman Chemical

Cannabidiol (exempt preparation)

Item № 90081
CAS № 13956-29-1
Purity ≥99%

Formulation:  A solution in methanol

     5 mg $92.00 0.00
     10 mg $112.00 0.00
     50 mg $460.00 0.00

Pricing updated 2018-03-20. Prices are subject to change without notice.

  • CBD

Cannabidiol is an active phytocannabinoid identified in Cannabis (composes ~40% of the plant's extract). Unlike Δ9-THC (Item No. 12068), cannabidiol is considered to be non-psychoactive.1 Cannabidiol has a very low affinity for CB1 and CB2 receptors but acts as an indirect antagonist and is thought to potentiate the effects of Δ9-THC.2 Cannabidiol is reported to act as an CB2 receptor inverse agonist, GPR55 antagonist, and a 5-HT1A receptor agonist.2,3,4,5 It can allosterically modulate μ and δ-opioid receptors as well as agonize PPARγ receptors and stimulate intracellular calcium release.6,7

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Technical Information
Formal Name
CAS Number
  • CBD
Molecular Formula
Formula Weight
A solution in methanol
209, 275 nm
InChI Code
InChI Key
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - no special processing required. For larger quantities or alternate sizes, please contact sales.

Warning - this product is not for human or veterinary use.

Shipping & Storage
Wet ice in continental US; may vary elsewhere
≥ 1 year
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References & Product Citations
Product Description References

1. Kozela, E.,Juknat, A.,Kaushansky, N., et al. Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells. J.Neuroinflamm. 12(52), (2015).

2. Mechoulam, R.,Peters, M.,Murillo-Rodriguez, E., et al. Cannabidiol - Recent advances. Chemistry & Biodiversity 4, 1678-1692 (2007).

3. Pertwee, R.G. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-Tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. Br. J. Pharmacol. 153(2), 199-215 (2008).

4. Ryberg, E.,Larsson, N.,Sjögren, S., et al. The orphan receptor GPR55 is a novel cannabinoid receptor. British Journal of Pharmacology 152, 1092-1101 (2007).

5. Russo, E.B.,Burnett, A.,Hall, B., et al. Agonistic properties of cannabidiol at 5-HT1a receptors. Neurochemical Research 30(8), 1037-1043 (2005).

6. Campos, A.C.,Moreira, F.A.,Gomes, F.V., et al. Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Phil.Trans.R.Soc.B. 367, 3364-3378 (2012).

7. Kathmann, M.,Flau, K.,Redmer, A., et al. Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors. Naunyn-Schmiedeberg's Arch.Pharmacol. 372(5), 354-361 (2006).

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