Cannabidiol (exempt preparation) (CAS 13956-29-1) | Cayman Chemical
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Cannabidiol (exempt preparation)

Item № 90081
CAS № 13956-29-1
Purity ≥99%
product image
                (CAS 13956-29-1)

Formulation:  A solution in methanol

SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     5 mg $92.00 0.00
     10 mg $112.00 0.00
     50 mg $460.00 0.00

Pricing updated 2018-11-16. Prices are subject to change without notice.

Description
Synonyms
  • CBD

Cannabidiol is an active phytocannabinoid identified in Cannabis (composes ~40% of the plant's extract). Unlike Δ9-THC (Item No. 12068), cannabidiol is considered to be non-psychoactive.1 Cannabidiol has a very low affinity for CB1 and CB2 receptors but acts as an indirect antagonist and is thought to potentiate the effects of Δ9-THC.2 Cannabidiol is reported to act as an CB2 receptor inverse agonist, GPR55 antagonist, and a 5-HT1A receptor agonist.2,3,4,5 It can allosterically modulate μ and δ-opioid receptors as well as agonize PPARγ receptors and stimulate intracellular calcium release.6,7

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Technical Information
Formal Name
2-[1R-3-methyl-6R-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol
CAS Number
13956-29-1
Synonyms
  • CBD
Molecular Formula
C21H30O2
Formula Weight
314.5
Purity
≥99%
Formulation
A solution in methanol
λmax
209, 275 nm
SMILES
O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@@H](O)C(C)(C)CCCC)C=C1
InChI Code
InChI=1S/C21H32O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h12-13,15,17-18,22-23H,2,5-11H2,1,3-4H3/t15-,17+,18-/m1/s1
InChI Key
CODIXLGYYWMJFS-BPQIPLTHSA-N
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - no special processing required. For larger quantities or alternate sizes, please contact sales.

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
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References & Product Citations
Product Description References

1. Kozela, E., Juknat, A., Kaushansky, N., et al. Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells J.Neuroinflamm. 12(52), (2015).

2. Mechoulam, R., Peters, M., Murillo-Rodriguez, E., et al. Cannabidiol - Recent advances Chemistry & Biodiversity 4, 1678-1692 (2007).

3. Pertwee, R.G. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-Tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin Br. J. Pharmacol. 153(2), 199-215 (2008).

4. Ryberg, E., Larsson, N., Sjögren, S., et al. The orphan receptor GPR55 is a novel cannabinoid receptor British Journal of Pharmacology 152, 1092-1101 (2007).

5. Russo, E.B., Burnett, A., Hall, B., et al. Agonistic properties of cannabidiol at 5-HT1a receptors Neurochemical Research 30(8), 1037-1043 (2005).

6. Campos, A.C., Moreira, F.A., Gomes, F.V., et al. Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders Phil.Trans.R.Soc.B. 367, 3364-3378 (2012).

7. Kathmann, M., Flau, K., Redmer, A., et al. Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors Naunyn-Schmiedeberg's Arch.Pharmacol. 372(5), 354-361 (2006).

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