Arachidonoyl Cyclopropylamide (CAS 229021-64-1) | Cayman Chemical
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Arachidonoyl Cyclopropylamide

Item № 91053
CAS № 229021-64-1
Purity ≥98%
product image
                (CAS 229021-64-1)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     5 mg $28.00 0.00
     10 mg $53.00 0.00
     50 mg $224.00 0.00
     100 mg $392.00 0.00

Pricing updated 2018-12-10. Prices are subject to change without notice.

Description
Synonyms
  • ACPA

Arachidonoyl cyclopropylamide (ACPA) is a potent and selective cannabinoid (CB) receptor 1 agonist with Ki values of 2.2 and 715 nM for CB1 and CB2 receptors, respectively.1 In whole animal experiments, ACPA induces hypothermia in mice with the same efficacy as arachidonoyl ethanolamide (AEA; Item No. 90050), in spite of its higher affinity for the CB1 receptor. These data have been interpreted to indicate that ACEA may be a substrate for fatty acid amide hydrolase (FAAH), and thus only transiently available in whole animal experiments.2

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Technical Information
Formal Name
N-cyclopropyl-5Z,8Z,11Z,14Z-eicosatetraenamide
CAS Number
229021-64-1
Synonyms
  • ACPA
Molecular Formula
C23H37NO
Formula Weight
343.6
Purity
≥98%
Formulation
A solution in ethanol
SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NC1CC1
InChI Code
InChI=1S/C23H37NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(25)24-22-20-21-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
InChI Key
GLGAUBPACOBAMV-DOFZRALJSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
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Additional Information

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References & Product Citations
Product Description References

1. Pertwee, R.G. Pharmacology of cannabinoid receptor ligands Curr. Med. Chem. 6(8), 635-664 (1999).

2. Hillard, C.J., Manna, S., Greenberg, M.J., et al. Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1) J. Pharmacol. Exp. Ther. 289(3), 1427-1433 (1999).

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