Biotin-PEG3-azide (CAS 875770-34-6) | Cayman Chemical
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Biotin-PEG3-azide

Item № 23419
CAS № 875770-34-6
Purity ≥95%
product image
                (CAS 875770-34-6)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     5 mg $25.00 0.00
     10 mg $45.00 0.00
     25 mg $100.00 0.00
     50 mg $150.00 0.00

Pricing updated 2018-11-19. Prices are subject to change without notice.

Description
Synonyms
  • Azide-PEG3-biotin

Biotin-PEG3-azide is a PEGylated version of biotin-azide (Item No. 13040) that is more hydrophilic due to the incorporation of a PEGylated spacer. It can be used to label terminal alkynes via copper-catalyzed click reactions or copper-free click reactions with cyclooctynes.1,2 Biotin-PEG3-azide has been used to non-enzymatically and covalently tag proteins, which can be separated and detected using common laboratory methods such as SDS-PAGE and Western blot.3 It can be used in combination with other protein tags. Biotin-PEG3-azide has also been used in nanostructured biointerfaces to study ligand and receptor spacing when there are different signaling molecules present.1

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Technical Information
Formal Name
(3aS,4S,6aR)-N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
CAS Number
875770-34-6
Synonyms
  • Azide-PEG3-biotin
Molecular Formula
C18H32N6O5S
Formula Weight
444.5
Purity
≥95%
Formulation
A crystalline solid
SMILES
O=C1N[C@@]2([H])[C@@](CS[C@H]2CCCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)([H])N1
InChI Code
InChI=1S/C18H32N6O5S/c19-24-21-6-8-28-10-12-29-11-9-27-7-5-20-16(25)4-2-1-3-15-17-14(13-30-15)22-18(26)23-17/h14-15,17H,1-13H2,(H,20,25)(H2,22,23,26)/t14-,15-,17-/m0/s1
InChI Key
ZWFOOMQCYIGZBE-ZOBUZTSGSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Schenk, F.C., Boehm, H., Spatz, J.P., et al. Dual-functionalized nanostructured bio-interfaces by click chemistry Langmuir 30(23), 6897-6905 (2014).

2. Nonaka, H., Tsukiji, S., Ojida, A., et al. Non-enzymatic covalent protein labeling using a reactive tag J. Am. Chem. Soc. 129(51), 15777-15779 (2007).

3. Lluis, M., Wang, Y., Monzingo, A.F., et al. Characterization of C-alkyl amidines as bioavailable covalent reversible inhibitors of human DDAH-1 Chem. Med. Chem. 6(1), 81-88 (2011).

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