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Epigenetics, Transcription, & Translation (163)

Erasers (10)

Histones/Histone Peptides (6)

Readers (163)

Bromodomains (114)

Chromodomains (8)

MBT Domains (5)

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Displaying 1 - 25 of 163 Results

(+)-JQ1

An inhibitor of BRD bromodomains

CAS No. 1268524-70-4

Item No. 11187

Formulation: A crystalline solid

Purity: ≥98%

1 mg

$31

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5 mg

$108

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10 mg

$154

Add

25 mg

$270

Add

Epigenetics Screening Library (96-Well)

For screening a variety of epigenetic compounds

Item No. 11076

Formulation: A 10 mM solution in DMSO

50 µl

$2,173

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I-BET151

A BRD2, BRD3, and BRD4 inhibitor

CAS No. 1300031-49-5

Item No. 11181

Formulation: A crystalline solid

Purity: ≥98%

GSK1210151A

1 mg

$40

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5 mg

$108

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10 mg

$197

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25 mg

$443

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(−)-JQ1

The inactive stereoisomer of a BET bromodomain inhibitor

CAS No. 1268524-71-5

Item No. 11232

Formulation: A crystalline solid

Purity: ≥98%

1 mg

$31

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5 mg

$108

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10 mg

$154

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25 mg

$270

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PCAF Histone Acetyltransferase (human, recombinant)

Active, pure human recombinant enzyme

Item No. 10009115

Formulation: 50 mM HEPES, pH 8, with 150 mM NaCl, 1 mM EDTA, and 20% glycerol

Purity: ≥80% estimated by SDS-PAGE

HAT
p300/(CREB binding protein) Associated Factor

100 µg

$541

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I-BET762

Inhibitor of BET proteins

CAS No. 1260907-17-2

Item No. 10676

Formulation: A crystalline solid

Purity: ≥98%

GSK525762A

1 mg

$36

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5 mg

$120

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10 mg

$219

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25 mg

$502

Add

OTX015

A BRD2, BRD3, and BRD4 inhibitor

CAS No. 202590-98-5

Item No. 15947

Formulation: A crystalline solid

Purity: ≥95%

HY-15743
(−)-OTX015

1 mg

$54

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5 mg

$172

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10 mg

$238

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BI-2536

A potent inhibitor of Plk1

CAS No. 755038-02-9

Item No. 17385

Formulation: A crystalline solid

Purity: ≥95%

1 mg

$41

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5 mg

$128

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10 mg

$196

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50 mg

$834

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L-Canaline

A natural inhibitor of aminotransferases

CAS No. 496-93-5

Item No. 9002357

Formulation: A crystalline solid

Purity: ≥95%

1 mg

$54

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5 mg

$238

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10 mg

$418

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25 mg

$913

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Anacardic Acid

A histone acetyltransferase inhibitor

CAS No. 16611-84-0

Item No. 13144

Formulation: A crystalline solid

Purity: ≥98%

6-pentadecyl Salicylic Acid

1 mg

$29

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5 mg

$53

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10 mg

$94

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MZ1

A PROTAC that drives BRD4 degradation

CAS No. 1797406-69-9

Item No. 21622

Formulation: A crystalline solid

Purity: ≥98%

500 µg

$53

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1 mg

$98

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5 mg

$433

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AZD 5153

A BRD4 inhibitor

CAS No. 1869912-39-9

Item No. 20864

Formulation: A crystalline solid

Purity: ≥95%

1 mg

$42

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5 mg

$194

Add

10 mg

$322

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25 mg

$653

Add

PFI-3

Probe for bromodomains of SMARCA2/4 and PB1(bromodomain 5)

CAS No. 1819363-80-8

Item No. 15267

Formulation: A crystalline solid

Purity: ≥98%

1 mg

$36

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5 mg

$103

Add

10 mg

$186

Add

25 mg

$420

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BRD4 bromodomain 1 (human, recombinant; His-tagged)

Host: E. coli • AA: 49-170 (partial protein) • Tag: N-terminal His • MW: 16.6 kDa

Item No. 11720

Formulation: 50 mM Tris, pH 8.0, with 500 mM NaCl, 5% glycerol, and 1 mM DTT

Purity: ≥90%

Bromodomain containing protein 4
HUNK1
MCAP
Mitotic Chromosome-associated Protein

100 µg

$401

Add

SGC-CBP30

A potent inhibitor of CREBBP/EP300 bromodomains

CAS No. 1613695-14-9

Item No. 14469

Formulation: A crystalline solid

Purity: ≥98%

5 mg

$121

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10 mg

$229

Add

50 mg

$894

Add

BRD4 bromodomain 1 (human, recombinant; GST-tagged)

Host: E. coli • AA: 49-170 • Tag: N-terminal GST • MW: 41.4 kDa

Item No. 11068

Formulation: 50 mM HEPES, pH 7.5, with 500 mM sodium chloride, 5 mM β-mercaptoethanol, and 5% glycerol

Purity: ≥95% estimated by SDS-PAGE

BRD4 BD1
Bromodomain containing protein 4
HUNK1
MCAP

100 µg

$382

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dBET1

A hybrid molecule containing (+)-JQ-1 and thalidomide

CAS No. 1799711-21-9

Item No. 18044

Formulation: A crystalline solid

Purity: ≥98%

1 mg

$49

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5 mg

$213

Add

10 mg

$400

Add

I-CBP112 (hydrochloride)

A p300 and CBP inhibitor

CAS No. 2147701-33-3

Item No. 14468

Formulation: A crystalline solid

Purity: ≥90%

1 mg

$49

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5 mg

$190

Add

10 mg

$283

Add

RVX-208

A selective BET bromodomain antagonist

CAS No. 1044870-39-4

Item No. 16424

Formulation: A crystalline solid

Purity: ≥98%

Apabetalone
RVX-000222

1 mg

$49

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5 mg

$120

Add

10 mg

$213

Add

25 mg

$445

Add

SGC Epigenetic Probe Set

A library of epigenetic probes from the Structural Genomics Consortium

Item No. 17748

1 ea

$3,003

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BRD4 bromodomains 1 and 2 (human, recombinant; aa 49-460)

Host: E. coli • AA: 49-460 • Tag: N-terminal GST • MW: 73.4 kDa

Item No. 11052

Formulation: 50 mM Hepes, pH 7.5, with 500 mM sodium chloride, 5% glycerol, and 5 mM β-mercaptoethanol

Purity: ≥65% estimated by SDS-PAGE

BRD4
Bromodomain containing protein 4
HUNK1
MCAP

100 µg

$401

Add

CPI-203

A bioavailable inhibitor of BET bromodomains

CAS No. 1446144-04-2

Item No. 15479

Formulation: A crystalline solid

Purity: ≥98%

1 mg

$63

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5 mg

$274

Add

10 mg

$454

Add

25 mg

$678

Add

ARV-825

A BRD4 inhibitor that drives BRD4 degradation

CAS No. 1818885-28-7

Item No. 21109

Formulation: A crystalline solid

Purity: ≥98%

500 µg

$54

Add

1 mg

$102

Add

5 mg

$444

Add

OICR-9429

A probe for WDR5

CAS No. 1801787-56-3

Item No. 16095

Formulation: A crystalline solid

Purity: ≥98%

1 mg

$63

Add

5 mg

$168

Add

10 mg

$242

Add

25 mg

$527

Add

I-BRD9

A BRD9 bromodomain inhibitor

CAS No. 1714146-59-4

Item No. 17749

Formulation: A crystalline solid

Purity: ≥98%

1 mg

$81

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5 mg

$159

Add

10 mg

$255

Add

50 mg

$1,064

Add

Displaying 1 - 25 of 163 Results

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New Products

Product TypeClear Filters

Research AreaClear Filters

ApplicationClear Filters

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A 10 mM solution in DMSO

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: 50 mM HEPES, pH 8, with 150 mM NaCl, 1 mM EDTA, and 20% glycerol

Purity: ≥80% estimated by SDS-PAGE

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥95%

Formulation: A crystalline solid

Purity: ≥95%

Formulation: A crystalline solid

Purity: ≥95%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥95%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: 50 mM Tris, pH 8.0, with 500 mM NaCl, 5% glycerol, and 1 mM DTT

Purity: ≥90%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: 50 mM HEPES, pH 7.5, with 500 mM sodium chloride, 5 mM β-mercaptoethanol, and 5% glycerol

Purity: ≥95% estimated by SDS-PAGE

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥90%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: 50 mM Hepes, pH 7.5, with 500 mM sodium chloride, 5% glycerol, and 5 mM β-mercaptoethanol

Purity: ≥65% estimated by SDS-PAGE

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%