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Analytical Chemistry (4)

Antibodies (14)

Assay & Reagent Kits (7)

Biochemicals (97)

Environmental Toxicology (1)

Lipids (3)

Natural Products (8)

Proteins (9)

Small Molecule Modulators (99)

Research AreaClear Filters

Cancer (143)

Angiogenesis (12)

Cancer Stem Cell Research (1)

Cell Cycle (6)

Cell Death (27)

Cell Migration & Metastasis (14)

Cell Signaling (143)

Abl family & Bcr-Abl Signaling (4)

ALK (Activin-like Kinase) Signaling (1)

Aurora Signaling (1)

cAMP Signaling (1)

ERK/MAPK Signaling (143)

Growth Factor Receptor Signaling (23)

GTPases (6)

JAK/STAT Signaling (4)

JNK Signaling (4)

NF-κB Signaling (6)

Nitric Oxide Signaling (1)

p38 MAPK Signaling (2)

PI3K/Akt/mTOR Signaling (17)

PKC Signaling (1)

ROCK Signaling (1)

S6K Signaling (1)

SRC Family Signaling (6)

Wnt Signaling (2)

DNA Damage and Repair (1)

Immunology (1)

Multidrug Resistance (4)

Transcription Factors (10)

Tumor Microenvironment (1)

Cardiovascular System (9)

Cell Biology (47)

Endocrinology & Metabolism (11)

Epigenetics, Transcription, & Translation (5)

Immunology & Inflammation (21)

Infectious Disease (4)

Lipid Biochemistry (4)

Neuroscience (10)

Oxidative Stress & Reactive Species (2)

Xenobiotic Metabolism (5)

ApplicationClear Filters

Cell-Based Assay (2)

ELISA (2)

Enzyme Activity (4)

High-Throughput Screening (7)

Immunocytochemistry (3)

Immunohistochemistry (12)

Mass Spectrometry (4)

TR-FRET (7)

Western Blot (14)

Displaying 1 - 25 of 143 Results

PD 0325901

A MEK inhibitor that sustains stem cell renewal

CAS No. 391210-10-9

Item No. 13034

Formulation: A crystalline solid

Purity: ≥90%

Mirdametinib

5 mg

$54

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10 mg

$97

Add

25 mg

$175

Add

50 mg

$270

Add

Nimbolide

An anticancer phytochemical

CAS No. 25990-37-8

Item No. 19230

Formulation: A crystalline solid

Purity: ≥97%

NSC 309909

5 mg

$277

Add

25 mg

$1,164

Add

PD 98059

A MAPK pathway inhibitor and AMPK activator

CAS No. 167869-21-8

Item No. 10006726

Formulation: A crystalline solid

Purity: ≥98%

NSC 679828

1 mg

$28

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5 mg

$62

Add

10 mg

$97

Add

50 mg

$345

Add

Trametinib

An inhibitor of MEK1 and MEK2

CAS No. 871700-17-3

Item No. 16292

Formulation: A crystalline solid

Purity: ≥95%

GSK1120212
JTP-74057

25 mg

$75

Add

50 mg

$105

Add

100 mg

$165

Add

250 mg

$374

Add

SCH 772984

A selective inhibitor of ERK1/2

CAS No. 942183-80-4

Item No. 19166

Formulation: A crystalline solid

Purity: ≥95%

1 mg

$44

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5 mg

$165

Add

10 mg

$220

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AG-1478

An inhibitor of EGF receptor kinase

CAS No. 153436-53-4

Item No. 10010244

Formulation: A crystalline solid

Purity: ≥98%

NSC 693255
Tyrphostin AG-1478

1 mg

$25

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5 mg

$105

Add

10 mg

$184

Add

25 mg

$400

Add

Dabrafenib

A Raf kinase inhibitor

CAS No. 1195765-45-7

Item No. 16989

Formulation: A crystalline solid

Purity: ≥98%

GSK2118436

5 mg

$42

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10 mg

$80

Add

50 mg

$209

Add

100 mg

$377

Add

SHP099

An orally bioavailable inhibitor of SHP2

CAS No. 1801747-42-1

Item No. 20000

Formulation: A crystalline solid

Purity: ≥98%

500 µg

$49

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1 mg

$93

Add

5 mg

$423

Add

10 mg

$748

Add

Protocatechuic Acid

A phenolic compound with antioxidant, anti-inflammatory, and anticancer properties

CAS No. 99-50-3

Item No. 14916

Formulation: A crystalline solid

Purity: ≥98%

NSC 16631
PCA

25 g

$49

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50 g

$86

Add

100 g

$152

Add

Regorafenib

A multi-kinase inhibitor

CAS No. 755037-03-7

Item No. 18498

Formulation: A crystalline solid

Purity: ≥98%

BAY 73-4506

5 mg

$49

Add

10 mg

$93

Add

25 mg

$130

Add

50 mg

$236

Add

PLX4032

An inhibitor of mutant V600E and wild type B-Raf

CAS No. 918504-65-1

Item No. 10618

Formulation: A crystalline solid

Purity: ≥98%

RG-7204
Ro 51-85426
Vemurafenib

5 mg

$49

Add

10 mg

$77

Add

25 mg

$178

Add

50 mg

$329

Add

CAY10561

A selective inhibitor of ERK

CAS No. 933786-58-4

Item No. 10010043

Formulation: A crystalline solid

Purity: ≥98%

Pyrazolylpyrrole ERK Inhibitor

500 µg

$29

Add

1 mg

$53

Add

5 mg

$215

Add

10 mg

$376

Add

PD 184161

A potent MEK1/2 inhibitor

CAS No. 212631-67-9

Item No. 10012431

Formulation: A crystalline solid

Purity: ≥98%

1 mg

$31

Add

5 mg

$129

Add

10 mg

$228

Add

25 mg

$493

Add

Encorafenib

An inhibitor of mutant B-Raf kinase

CAS No. 1269440-17-6

Item No. 16994

Formulation: A crystalline solid

Purity: ≥98%

LGX818

500 µg

$41

Add

1 mg

$77

Add

5 mg

$180

Add

SL 0101-1

A selective inhibitor of RSK

CAS No. 77307-50-7

Item No. 11704

Formulation: A crystalline solid

Purity: ≥95%

500 µg

$63

Add

1 mg

$110

Add

5 mg

$435

Add

10 mg

$602

Add

AZD 6244

A highly selective inhibitor of MEK1/2

CAS No. 606143-52-6

Item No. 11599

Formulation: A crystalline solid

Purity: ≥95%

ARRY-142886
CL 1,040
NSC 741O78
Selumetinib

10 mg

$36

Add

25 mg

$61

Add

50 mg

$95

Add

100 mg

$120

Add

ARS853

An inhibitor of KRAS^G12C

CAS No. 1629268-00-3

Item No. 19137

Formulation: A crystalline solid

Purity: ≥95%

500 µg

$134

Add

1 mg

$253

Add

5 mg

$662

Add

10 mg

$926

Add

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

A food-derived carcinogen

CAS No. 105650-23-5

Item No. 22590

Formulation: A crystalline solid

Purity: ≥98%

PhIP

1 mg

$32

Add

5 mg

$128

Add

10 mg

$208

Add

Cobimetinib

A potent, orally available MEK1 inhibitor

CAS No. 934660-93-2

Item No. 19563

Formulation: A crystalline solid

Purity: ≥98%

GDC-0973
RG-7420
XL518

1 mg

$54

Add

5 mg

$197

Add

10 mg

$367

Add

25 mg

$783

Add

Trametinib-¹³C-d₃

An internal standard for the quantification of trametinib

CAS No. 2712126-59-3

Item No. 29144

Formulation: A solid

Purity: ≥99% deuterated forms (d₁-d₃)

1 mg

$436

Add

Binimetinib

A MEK1/2 inhibitor

CAS No. 606143-89-9

Item No. 16996

Formulation: A crystalline solid

Purity: ≥98%

ARRY-438162
MEK162

5 mg

$35

Add

10 mg

$53

Add

50 mg

$123

Add

100 mg

$228

Add

ZM 336372

An activator of the Raf-1 signalling pathway

CAS No. 208260-29-1

Item No. 10010367

Formulation: A crystalline solid

Purity: ≥98%

1 mg

$48

Add

5 mg

$94

Add

10 mg

$160

Add

25 mg

$343

Add

MRTX-849

A covalent inhibitor of K-Ras^G12C

CAS No. 2326521-71-3

Item No. 31440

Formulation: A crystalline solid

Purity: ≥98%

Adagrasib

1 mg

$49

Add

5 mg

$182

Add

10 mg

$291

Add

SB-590885

A potent inhibitor of B-Raf

CAS No. 405554-55-4

Item No. 16643

Formulation: A crystalline solid

Purity: ≥98%

1 mg

$54

Add

5 mg

$132

Add

10 mg

$209

Add

25 mg

$458

Add

Ulixertinib (hydrochloride)

An ERK1/2 inhibitor

CAS No. 1956366-10-1

Item No. 18298

Formulation: A crystalline solid

Purity: ≥98%

BVD-523
VRT-752271

1 mg

$32

Add

5 mg

$71

Add

10 mg

$109

Add

25 mg

$156

Add

Displaying 1 - 25 of 143 Results

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Product TypeClear Filters

Research AreaClear Filters

ApplicationClear Filters

Formulation: A crystalline solid

Purity: ≥90%

Formulation: A crystalline solid

Purity: ≥97%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥95%

Formulation: A crystalline solid

Purity: ≥95%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥95%

Formulation: A crystalline solid

Purity: ≥95%

Formulation: A crystalline solid

Purity: ≥95%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A solid

Purity: ≥99% deuterated forms (d1-d3)

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Formulation: A crystalline solid

Purity: ≥98%

Purity: ≥99% deuterated forms (d₁-d₃)